An Overview of the Immune Dysregulation in COVID-19 with Immunization Priority in the Indian Context

An Overview of the Immune Dysregulation in COVID-19 with Immunization Priority in the Indian Context

Dr. Aditi Munmun Sengupta Medical Officer, CK Birla Hospitals; Research Scholar, University of Calcutta; Harvard Medical School, Post Graduate Association Member; Life member,Indian Science Congress Association.

Contact

Diptendu Chatterjee

Contact

Salil Kumar Bhattacharya

Contact

Rima Ghosh

Contact

University of Calcutta

An Overview of the Immune Dysregulation in COVID-19 with Immunization Priority in the Indian Context

Article Fingerprint

ReserarchID

BCPU9

An Overview of the Immune Dysregulation in COVID-19 with Immunization Priority in the Indian Context Banner

AI TAKEAWAY

Connecting with the Eternal Ground

Abstract

The review was aimed at understanding the immune dysregulation by the novel virus, COVID-19. The review also highlighted the major findings that have been published in the previous studies through secondary research about the mechanism of immune dysregulation, transmission and progression of the virus across the globe. Adults above the age of 60 years and with co-morbidities such as cardiac and renal dysfunction, hypertension and diabetes are predisposed to greater risk of COVID-19 infection. The virus impairs the physiological, psychological and metabolic functioning of the patient. The paper gained an insight into the need for immunization priority for the Indian population and recommendations for the effective policy making in vaccine development and distribution.

References

42 Cites in Article

Reference Format

Janelle Ayres (2020). A metabolic handbook for the COVID-19 pandemic.
A Azkur,M Akdis,D Azkur,M Sokolowska,W Van De Veen,M Brüggen,. Akdis,C (2020). Immune response to SARS-CoV-2 and mechanisms of immunopathological changes in COVID-19.
C Binns,W Low,L Kyung (2020). The COVID-19 Pandemic: Public Health and Epidemiology.
S Brosnahan,A Jonkman,M Kugler,J Munger,D Kaufman (2020). COVID-19 and Respiratory System Disorders: Current Knowledge, Future Clinical and Translational Research Questions.
T Burki (2020). The Russian vaccine for COVID-19.
Gyaneshwer Chaubey (2020). Coronavirus (SARS-CoV-2) and Mortality Rate in India: The Winning Edge.
Wen-Hsiang Chen,Ulrich Strych,Peter Hotez,Maria Bottazzi (2020). The SARS-CoV-2 Vaccine Pipeline: an Overview.
S Chinnaswamy (2020). SARS-CoV-2 infection in India bucks the trend: Trained innate immunity?.
Mohammad Chowdhury,Nayem Hossain,Mohammod Kashem,Md. Shahid,Ashraful Alam (2020). Immune response in COVID-19: A review.
S Deo,S Manurkar,S Krishnan,C Franz (2020). Brief Critical Review of COVID-19 Vaccine Distribution Frameworks.
Paramjit Dhot,Pandeep Bhatia,Tarundeep Dhot,Trupti Barot (2020). Guidelines on Covid-19 for Blood Banks.
S Dubey,P Biswas,R Ghosh,S Chatterjee,M Dubey,S Chatterjee,. Lavie,C (2020). Psychosocial impact of COVID-19.
Benjamin Gallo Marin,Ghazal Aghagoli,Katya Lavine,Lanbo Yang,Emily Siff,Silvia Chiang,Thais Salazar‐mather,Luba Dumenco,Michael Savaria,Su Aung,Timothy Flanigan,Ian Michelow (2020). Predictors of <scp>COVID</scp>‐19 severity: A literature review.
E Giamarellos-Bourboulis,M Netea,N Rovina,K Akinosoglou,A Antoniadou,N Antonakos,. Ntaganou,M (2020). Complex immune dysregulation in COVID-19 patients with severe respiratory failure.
Alexander Gorbalenya,Susan Baker,Ralph Baric,Raoul De Groot,Christian Drosten,Anastasia Gulyaeva,Bart Haagmans,Chris Lauber,Andrey Leontovich,Benjamin Neuman,Dmitry Penzar,Stanley Perlman,Leo Poon,Dmitry Samborskiy,Igor Sidorov,Isabel Sola,John Ziebuhr (2020). The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2.
W Guan,Z Ni,Y Hu,W Liang,C Ou,J He,. Du,B (2020). Clinical characteristics of coronavirus disease 2019 in China.
Bing He,Jun Wang,Yudie Wang,Juan Zhao,Juan Huang,Yu Tian,Cheng Yang,Heng Zhang,Mingxia Zhang,Lixing Gu,Xiaocui Zhou,Jingjiao Zhou (2020). The Metabolic Changes and Immune Profiles in Patients With COVID-19.
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jiaan Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Hui Li,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guangfa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao (2020). Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.
Wei Huang,Julie Berube,Michelle Mcnamara,Suraj Saksena,Marsha Hartman,Tariq Arshad,Scott Bornheimer,Maurice O'gorman (2020). Lymphocyte Subset Counts in <scp>COVID</scp>‐19 Patients: A Meta‐Analysis.
(2020). Coronavirus: India likely had 6.4 million infections in May:ICMRSerosurvey.
(2020). 9,177,840 Cases and 134,254 Deaths -Worldometer.
Wei Ji,Wei Wang,Xiaofang Zhao,Junjie Zai,Xingguang Li (2020). Cross‐species transmission of the newly identified coronavirus 2019‐nCoV.
Raghuvir Keni,Anila Alexander,Pawan Nayak,Jayesh Mudgal,Krishnadas Nandakumar (2020). COVID-19: Emergence, Spread, Possible Treatments, and Global Burden.
T Le,Z Andreadakis,A Kumar,R Roman,S Tollefsen,M Saville,S Mayhew (2020). The COVID-19 vaccine development landscape.
Yingxia Liu,Yang Yang,Cong Zhang,Fengming Huang,Fuxiang Wang,Jing Yuan,Zhaoqin Wang,Jinxiu Li,Jianming Li,Cheng Feng,Zheng Zhang,Lifei Wang,Ling Peng,Li Chen,Yuhao Qin,Dandan Zhao,Shuguang Tan,Lu Yin,Jun Xu,Congzhao Zhou,Chengyu Jiang,Lei Liu (2020). Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury.
Esmaeil Mortaz,Payam Tabarsi,Mohammad Varahram,Gert Folkerts,Ian Adcock (2020). The Immune Response and Immunopathology of COVID-19.
Veronica Nisticò,Diana Goeta,Orsola Gambini,Benedetta Demartini (2020). The psychological impact of COVID-19 among a sample of Italian patients with functional neurological disorders: A preliminary study.
E Ong,Y Chan,W Leong,N Lee,S Kalimuddin,S Mohideen,. Low,J (2020). A dynamic immune response shapes COVID-19 progression.
T Praveen,D Desai,M Soneja,N Wig (2020). Immune dysregulation in COVID-19 and its therapeutic implications.
E Prompetchara,C Ketloy,T &palaga (2020). Immune responses in COVID-19 and potential vaccines: Lessons learned from SARS and MERS epidemic.
K Rao,V Suryaprakash,R Senthilkumar,S Preethy,S Katoh,N Ikewaki,S Abraham (2020). Role of immune dysregulation in increased mortality among a specific subset of COVID-19 patients and immune-enhancement strategies for combatting through nutritional supplements.
Jason Schwartz (2020). Evaluating and Deploying Covid-19 Vaccines — The Importance of Transparency, Scientific Integrity, and Public Trust.
Mary Bohn,Shannon Steele,Khosrow Adeli (2020). SARS-CoV-2 serology in pediatrics: Seroprevalence studies in unvaccinated children and humoral antibody response post vaccination.
Yufang Shi,Ying Wang,Changshun Shao,Jianan Huang,Jianhe Gan,Xiaoping Huang,Enrico Bucci,Mauro Piacentini,Giuseppe Ippolito,Gerry Melino (2020). COVID-19 infection: the perspectives on immune responses.
S Singh,R Maurya,R Singh (2020). Trained immunity" from Mycobacterium spp. exposure or BCG vaccination and COVID-19 outcomes.
Daniel Speiser,Martin Bachmann (2020). COVID-19: Mechanisms of Vaccination and Immunity.
R Verity,L Okell,I Dorigatti,P Winskill,C Whittaker,N Imai,. Dighe,A (2020). Estimates of the severity of coronavirus disease 2019: a model-based analysis.
Saurabhrambiharilal Shrivastava,Prateeksaurabh Shrivastava (2020). COVID-19 pandemic: Ensuring health system sustainability through strengthening immunization activities.
Ivan Kodvanj,Jan Homolak,Davor Virag,Vladimir Trkulja (2020). World Health Organization (WHO) COVID-19 Database: Who Needs It?.
Litao Zhang,Xinsheng Yan,Qingkun Fan,Haiyan Liu,Xintian Liu,Zejin Liu,Zhenlu Zhang (2020). D‐dimer levels on admission to predict in‐hospital mortality in patients with Covid‐19.
Y Zhao,Y Shang,W Song,Q Li,H Xie,Q Xu,. Luo,H (2020). Follow-up study of the pulmonary function and related physiological characteristics of COVID-19 survivors three months after recovery.
Zhaohai Zheng,Fang Peng,Buyun Xu,Jingjing Zhao,Huahua Liu,Jiahao Peng,Qingsong Li,Chongfu Jiang,Yan Zhou,Shuqing Liu,Chunji Ye,Peng Zhang,Yangbo Xing,Hangyuan Guo,Weiliang Tang (2020). Risk factors of critical & mortal COVID-19 cases: A systematic literature review and meta-analysis.

Download References

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Dr. Aditi Munmun Sengupta. 2021. \u201cAn Overview of the Immune Dysregulation in COVID-19 with Immunization Priority in the Indian Context\u201d. Global Journal of Medical Research - K: Interdisciplinary GJMR-K Volume 20 (GJMR Volume 20 Issue K14).

More Citation Formats

Select Citation Style:

Download Citation

GJMR Volume 20 Issue K14

Explore Journals Explore Volume Read This Issue

Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

Not Found

Classification

GJMR-K Classification NLMC Code: WD 308

Submission ReceivedDecember 7, 2019
Peer Review Double Blind
Handling Editor
Accepted January 4, 2020
Published January 15, 2020

Version of record

v1.2

Issue date

January 6, 2021

Language

Experiance in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

View in VR

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

View in 3D

Article Matrices

Total Views: 2263

Total Downloads: 1145

2026 Trends

Our website is actively being updated, and changes may occur frequently. Please clear your browser cache if needed. For feedback or error reporting, please email [email protected]