An Unusual Manifestation of Hughes-Stovin Syndrome – Case Report

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Monica Pon
Monica Pon
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Heng Man Lai
Heng Man Lai
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Chi Kun Mok
Chi Kun Mok
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Hio Wai Ieong
Hio Wai Ieong
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Ka Pou Mok
Ka Pou Mok
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Hou Ng
Hou Ng
α Hospital Conde S. Januário

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An Unusual Manifestation of Hughes-Stovin Syndrome – Case Report

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Abstract

Abstarct-Hughes-Stovin syndrome (HSS) is very rare systemic disorder characterized by the combination of widespread vascular thrombosis and pulmonary vasculitis with serious morbidity and mortality. The exact etiology and pathogenesis of Hughes-Stovin syndrome is unknown. The clinical presentation of Hughes-Stovin syndrome includes hemoptysis, cough, dyspnea, fever and chest pain. Nearly 25% of patients with Hughes-Stovin syndrome develop vascular thromboembolism, arterial aneurysms, and arterial and venous occlusions with nonspecific vasculitis. The vascular lesion was most common in both artery and vein (68%), followed by vein (25%) and artery (8%). We report a case of a 56-years-old male patient presenting with fever of unknown origin. During the diagnostic work up, incidentally found aneurysm formation and thrombosis in the left upper lobe pulmonary artery segmental branch, thrombosis of the right lower lobe pulmonary artery segmental branches.

References

6 Cites in Article
  1. Umair Khalid,Taimur Saleem (2011). Hughes-Stovin Syndrome.
  2. Y Emad,Y Ragab,M Kechida (2021). A critical analysis of 57 cases of Hughes-Stovin syndrome (HSS). A report by the HSS International Study Group (HSSISG).
  3. Al-Jahdali (2010). Massive hemoptysis and deep venous thrombosis presenting in a woman with Hughes-Stovin syndrome: a case report.
  4. Athanasios Chalazonitis,Stefanos Lachanis,Panagiotis Mitseas,Panagiotis Argyriou,Joannie Tzovara,Petros Porfyrides,Evangelia Sotiropoulou,Nikolaos Ptohis (2009). Hughes-Stovin Syndrome: a case report and review of the literature.
  5. Yasser Emad,Yasser Ragab,Abd El-Hakim Shawki,Tamer Gheita,Ahmed El-Marakbi,Mohamed Salama (2007). Hughes–Stovin syndrome: is it incomplete Behçet’s?.
  6. K Nishi,S Myou,T Ooka,M Fujimura,T Matsuda (1994). Diffuse cutaneous systemic sclerosis associated with pan-serositis, disseminated intravascular coagulation, and diffuse alveolar haemorrhage.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Monica Pon. 2026. \u201cAn Unusual Manifestation of Hughes-Stovin Syndrome – Case Report\u201d. Global Journal of Medical Research - F: Diseases GJMR-F Volume 22 (GJMR Volume 22 Issue F2): .

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A detailed view of Hughes-Stovin Syndrome's manifestations and case report insights.
Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords
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GJMR-F Classification: NLMC Code: WD 305
Version of record

v1.2

Issue date

February 28, 2022

Language
en
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Published Article

Abstarct-Hughes-Stovin syndrome (HSS) is very rare systemic disorder characterized by the combination of widespread vascular thrombosis and pulmonary vasculitis with serious morbidity and mortality. The exact etiology and pathogenesis of Hughes-Stovin syndrome is unknown. The clinical presentation of Hughes-Stovin syndrome includes hemoptysis, cough, dyspnea, fever and chest pain. Nearly 25% of patients with Hughes-Stovin syndrome develop vascular thromboembolism, arterial aneurysms, and arterial and venous occlusions with nonspecific vasculitis. The vascular lesion was most common in both artery and vein (68%), followed by vein (25%) and artery (8%). We report a case of a 56-years-old male patient presenting with fever of unknown origin. During the diagnostic work up, incidentally found aneurysm formation and thrombosis in the left upper lobe pulmonary artery segmental branch, thrombosis of the right lower lobe pulmonary artery segmental branches.

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An Unusual Manifestation of Hughes-Stovin Syndrome – Case Report

Monica Pon
Monica Pon Hospital Conde S. Januário
Heng Man Lai
Heng Man Lai
Chi Kun Mok
Chi Kun Mok
Hio Wai Ieong
Hio Wai Ieong
Ka Pou Mok
Ka Pou Mok
Hou Ng
Hou Ng

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