Analysis of the Bacterial Vaginosis Predictive Significance In The Diagnosis of Inflammatory Processes in Female Pelvic Minor

α
Dr. Dragan Loncar
Dr. Dragan Loncar
σ
Dr. Dragan LonAar
Dr. Dragan LonAar
α University of Kragujevac University of Kragujevac

Send Message

To: Author

Analysis of the Bacterial Vaginosis Predictive Significance In The Diagnosis of Inflammatory Processes in Female Pelvic Minor

Article Fingerprint

ReserarchID

VY980

Analysis of the Bacterial Vaginosis Predictive Significance In The Diagnosis of Inflammatory Processes in Female Pelvic Minor Banner

AI TAKEAWAY

Connecting with the Eternal Ground
  • English
  • Afrikaans
  • Albanian
  • Amharic
  • Arabic
  • Armenian
  • Azerbaijani
  • Basque
  • Belarusian
  • Bengali
  • Bosnian
  • Bulgarian
  • Catalan
  • Cebuano
  • Chichewa
  • Chinese (Simplified)
  • Chinese (Traditional)
  • Corsican
  • Croatian
  • Czech
  • Danish
  • Dutch
  • Esperanto
  • Estonian
  • Filipino
  • Finnish
  • French
  • Frisian
  • Galician
  • Georgian
  • German
  • Greek
  • Gujarati
  • Haitian Creole
  • Hausa
  • Hawaiian
  • Hebrew
  • Hindi
  • Hmong
  • Hungarian
  • Icelandic
  • Igbo
  • Indonesian
  • Irish
  • Italian
  • Japanese
  • Javanese
  • Kannada
  • Kazakh
  • Khmer
  • Korean
  • Kurdish (Kurmanji)
  • Kyrgyz
  • Lao
  • Latin
  • Latvian
  • Lithuanian
  • Luxembourgish
  • Macedonian
  • Malagasy
  • Malay
  • Malayalam
  • Maltese
  • Maori
  • Marathi
  • Mongolian
  • Myanmar (Burmese)
  • Nepali
  • Norwegian
  • Pashto
  • Persian
  • Polish
  • Portuguese
  • Punjabi
  • Romanian
  • Russian
  • Samoan
  • Scots Gaelic
  • Serbian
  • Sesotho
  • Shona
  • Sindhi
  • Sinhala
  • Slovak
  • Slovenian
  • Somali
  • Spanish
  • Sundanese
  • Swahili
  • Swedish
  • Tajik
  • Tamil
  • Telugu
  • Thai
  • Turkish
  • Ukrainian
  • Urdu
  • Uzbek
  • Vietnamese
  • Welsh
  • Xhosa
  • Yiddish
  • Yoruba
  • Zulu

Abstract

Pelvic inflammatory disease (PID) occurs with the incidence of 100 -200/ 100 000. The aim of this study was to determine whether there is a correlation between serum proinflammatory cytokines IL-1β and IFN-γ and the presence of bacterial vaginosis (BV) or Chlamydia infections (Chl) in women with symptoms of inflammatory processes in the pelvic minor. The study included fifty patients diagnosed with PID with the average age of 32 years. The results of this study reveal that women with bacterial vaginoses and PID level of IL-1β in serum is increased, whereas in women with Chlamydial infection and PID serum level of IFN-γ is increased. The study showed that in patients with PID, in whom there was no diagnosis of BV and infection with Chlamydia trachomatis, the levels of IL-1β and IFN-γ are increased. The conclusion of this research points out to the importance of monitoring levels of cytokines in patients with homeostasis of vaginal flora disorders in the prevention of PID.

References

18 Cites in Article
  1. Martha Alvarez-Olmos,Melissa Barousse,Latta Rajan,Barbara Van Der Pol,Dennis Fortenberry,Donald Orr,Paul Fidel (2004). Vaginal Lactobacilli in Adolescents.
  2. Richard Amsel,Patricia Totten,Carol Spiegel,Kirk Chen,David Eschenbach,King Holmes (1983). Nonspecific vaginitis.
  3. B Basso,F Gimenez,C Lopez (2005). IL1b, IL6 and IL8 levels in gyneco obstetric infections.
  4. Sabina Cauci,Silvia Driussi,Secondo Guaschino,Miriam Isola,Franco Quadrifoglio (2002). Correlation of Local Interleukin‐1beta Levels with Specific IgA Response Against <i>Gardnerella vaginalis</i> Cytolysin in Women with Bacterial Vaginosis.
  5. A Curry,I Vogel,C Drews,D Schendel,K Skogstrand,W Flander (2007). Midpregnancy plasma levels of interleukin 2, 6, and 12, tumor necrosis factoralpha, interferongamma and granulocyte macrophage colonystimulating factor and spotaneous preterm delivery.
  6. M Golden (2003). Vaginitis and sexually transmitted diseases.
  7. R Gupta,H Vardhan,P Srivastava,S Salhan,A (2009). Modulation of cytokines and transcription factors (TBet and GATA3) in CD4 enriched cervical cells of Chlamydia trachomatis infected fertile and infertile women upon stimulation with chlamydial inclusion membrane proteins B and C.
  8. S Hedges,F Barrientes,R Desmond,J Schwebke (2006). Local and systemic cytokine levels in relation to changes in vaginal flora.
  9. Sharon Hillier,Marijane Krohn,Lorna Rabe,Seymour Klebanoff,David Eschenbach (1993). The Normal Vaginal Flora, H2O2-Producing Lactobacilli, and Bacterial Vaginosis in Pregnant Women.
  10. Hytham Imseis,Phillip Greig,Charles Livengood,Emily Shunior,Paul Durda,Mark Erikson (1997). Characterization of the Inflammatory Cytokines in the Vagina During Pregnancy and Labor and With Bacterial Vaginosis.
  11. Jovan Rajčević,Dragan Pejić,Đorđe Novaković,Novica Marković,Nemanja Gazivoda (2000). Мерење подужне електричне отпорности цеви нафтовода.
  12. Roberta Ness,Hugh Randall,Holly Richter,Jeffrey Peipert,Andrea Montagno,David Soper,Richard Sweet,Deborah Nelson,Diane Schubeck,Susan Hendrix,Debra Bass,Kevin Kip (2004). Condom Use and the Risk of Recurrent Pelvic Inflammatory Disease, Chronic Pelvic Pain, or Infertility Following an Episode of Pelvic Inflammatory Disease.
  13. R Nugent,M Krohn,S Hillier (1991). Reliability of diagnosing bacterial vaginosis is improved by a standardized method of gram stain interpretation.
  14. Beatrice Ondondo,Robert Brunham,William Harrison,Teresa Kinyari,Prameet Sheth,Nelly Mugo,Craig Cohen (2009). Frequency and Magnitude of<i>Chlamydia trachomatis</i>Elementary Body– and Heat Shock Protein 60–Stimulated Interferon γ Responses in Peripheral Blood Mononuclear Cells and Endometrial Biopsy Samples from Women with High Exposure to Infection.
  15. L Pickering (2006). Pelvic inflammatory disease.
  16. David Soper,P Mead (2005). Infections of the Female Pelvis.
  17. S Spandorfer,A Neuer,P Giraldo,Z Rosenwaks,S Witkin (2001). Relationship of abnormal vaginal flora, proinflammatory cytokines and idiopathic infertility in women undergoing IVF.
  18. Pragya Srivastava,Rajneesh Jha,Sylvette Bas,Sudha Salhan,Aruna Mittal (2008). In infertile women, cells from Chlamydia trachomatis infected site release higher levels of interferon-gamma, interleukin-10 and tumor necrosis factor-alpha upon heat shock protein stimulation than fertile women.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Dr. Dragan Loncar. 1970. \u201cAnalysis of the Bacterial Vaginosis Predictive Significance In The Diagnosis of Inflammatory Processes in Female Pelvic Minor\u201d. Global Journal of Medical Research - H: Orthopedic & Musculoskeletal System N/A (GJMR Volume 11 Issue H5): .

Download Citation

Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Version of record

v1.2

Issue date

Language
en
Experiance in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

Article Matrices
Total Views: 20912
Total Downloads: 11262
2026 Trends
Related Research

Published Article

Pelvic inflammatory disease (PID) occurs with the incidence of 100 -200/ 100 000. The aim of this study was to determine whether there is a correlation between serum proinflammatory cytokines IL-1β and IFN-γ and the presence of bacterial vaginosis (BV) or Chlamydia infections (Chl) in women with symptoms of inflammatory processes in the pelvic minor. The study included fifty patients diagnosed with PID with the average age of 32 years. The results of this study reveal that women with bacterial vaginoses and PID level of IL-1β in serum is increased, whereas in women with Chlamydial infection and PID serum level of IFN-γ is increased. The study showed that in patients with PID, in whom there was no diagnosis of BV and infection with Chlamydia trachomatis, the levels of IL-1β and IFN-γ are increased. The conclusion of this research points out to the importance of monitoring levels of cytokines in patients with homeostasis of vaginal flora disorders in the prevention of PID.

Our website is actively being updated, and changes may occur frequently. Please clear your browser cache if needed. For feedback or error reporting, please email [email protected]

Request Access

Please fill out the form below to request access to this research paper. Your request will be reviewed by the editorial or author team.
X

Quote and Order Details

Contact Person

Invoice Address

Notes or Comments

This is the heading

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.

High-quality academic research articles on global topics and journals.

Analysis of the Bacterial Vaginosis Predictive Significance In The Diagnosis of Inflammatory Processes in Female Pelvic Minor

Dr. Dragan LonAar
Dr. Dragan LonAar

Research Journals