Analytical Method for Estimation of Losartan by using UV a Spectrophotometer

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Dr. Safila Naveed
Dr. Safila Naveed
α Jinnah University for Women

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Analytical Method for Estimation of Losartan by using UV a Spectrophotometer

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Abstract

A simple, accurate, and economical least time consuming method for losartan method has been developed using Uv spectrophotometer.The assay is based on the UV absorbance maxima at about wavelength of 234nm using distilled water as solvent. Six sample of drug were dissolved in distilled water to produce solutions containing different brands of losartan. The absorbance of these six drugs were measured at 234 nm against the solvent blank and the assay were calculated by using the absorbance of active.This method can be used for the quality control QC quantitation and analysis of losartan in active and tablet formulations.

References

6 Cites in Article
  1. Giuseppe Carlucci,Giancarlo Palumbo,Pietro Mazzeo,Maria Giovanna Quaglia (2000). Simultaneous determination of losartan and hydrochlorothiazide in tablets by high-performance liquid chromatography.
  2. Maria Del Rosario,B Contreras,Y Clavijo,S Torres,D Delgado,Y (2009). Determination of Losartan, Telmisartan, and Valsartan by Direct Injection of Human Urine into a Column-Switching Liquid Chromatographic System with Fluorescence Detection.
  3. R Williams,M Alasandro,V Fasone,R Boucher,J Edwards (1996). Comparison of liquid chromat-ography, capillary electrophoresis and super-critical fluid chromatography in the determination of Losartan Potassium drug substance in Cozaar tablets.
  4. H Habib,S Weshahy,S Toubar,Mma El-Alamin (2008). Cathodic Stripping Voltammetric 100 100.
  5. Olga Lastra,Igor Lemus,Hugo Sánchez,Renato Pérez (2003). Development and validation of an UV derivative spectrophotometric determination of Losartan potassium in tablets.
  6. A Ensafi,R Hajian (2008). Determination of losartan and triamterene in pharmaceutical compounds and urine using cathodic adsorptive stripping voltammetry.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Dr. Safila Naveed. 2014. \u201cAnalytical Method for Estimation of Losartan by using UV a Spectrophotometer\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 14 (GJMR Volume 14 Issue B4): .

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Version of record

v1.2

Issue date

September 4, 2014

Language
en
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Published Article

A simple, accurate, and economical least time consuming method for losartan method has been developed using Uv spectrophotometer.The assay is based on the UV absorbance maxima at about wavelength of 234nm using distilled water as solvent. Six sample of drug were dissolved in distilled water to produce solutions containing different brands of losartan. The absorbance of these six drugs were measured at 234 nm against the solvent blank and the assay were calculated by using the absorbance of active.This method can be used for the quality control QC quantitation and analysis of losartan in active and tablet formulations.

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Analytical Method for Estimation of Losartan by using UV a Spectrophotometer

Dr. Safila Naveed
Dr. Safila Naveed Jinnah University for Women

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