Anti-Ulcer Activity of Rhus Coriaria in Indomethacin and Water Immersion Restraint Induced Gastric Ulcer in Experimental Rats

1
Haqeeq Ahmad
Haqeeq Ahmad
2
Abdul Wadud
Abdul Wadud
3
Nasreen Jahan
Nasreen Jahan
4
Izharul Hasan
Izharul Hasan
1 Rajiv gandhi university, Karnataka

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The anti-ulcer activity of hydro alcoholic extract of Rhus coriaria Linn (HAERC) was investigated in Indomethacin and Water immersion-induced restraint gastric ulcer in Wistar rats. The assessment was carried out by using ulcer index, ulcer score and histopathological studies of the specimens. HAERC at doses of 145 and 248 mg/kg given orally produced significant inhibition of the gastric lesions induced by Indomethacin and Water Immersion restraint method and the results were comparable to the standard treatment regime. We observed that Rhus coriaria Linn extract exhibits significant anti ulcer activity and thus supports the Unani claims about the drug.

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No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

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No ethics committee approval was required for this article type.

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Not applicable for this article.

Haqeeq Ahmad. 2015. \u201cAnti-Ulcer Activity of Rhus Coriaria in Indomethacin and Water Immersion Restraint Induced Gastric Ulcer in Experimental Rats\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 14 (GJMR Volume 14 Issue B7): .

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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January 19, 2015

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English

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The anti-ulcer activity of hydro alcoholic extract of Rhus coriaria Linn (HAERC) was investigated in Indomethacin and Water immersion-induced restraint gastric ulcer in Wistar rats. The assessment was carried out by using ulcer index, ulcer score and histopathological studies of the specimens. HAERC at doses of 145 and 248 mg/kg given orally produced significant inhibition of the gastric lesions induced by Indomethacin and Water Immersion restraint method and the results were comparable to the standard treatment regime. We observed that Rhus coriaria Linn extract exhibits significant anti ulcer activity and thus supports the Unani claims about the drug.

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Anti-Ulcer Activity of Rhus Coriaria in Indomethacin and Water Immersion Restraint Induced Gastric Ulcer in Experimental Rats

Haqeeq Ahmad
Haqeeq Ahmad Rajiv gandhi university, Karnataka
Abdul Wadud
Abdul Wadud
Nasreen Jahan
Nasreen Jahan
Izharul Hasan
Izharul Hasan

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