Anti-Ulcer Activity of Rhus Coriaria in Indomethacin and Water Immersion Restraint Induced Gastric Ulcer in Experimental Rats

Anti-Ulcer Activity of Rhus Coriaria in Indomethacin and Water Immersion Restraint Induced Gastric Ulcer in Experimental Rats

Haqeeq Ahmad

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Abdul Wadud

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Nasreen Jahan

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Izharul Hasan

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α Rajiv Gandhi University of Health Sciences

Anti-Ulcer Activity of Rhus Coriaria in Indomethacin and Water Immersion Restraint Induced Gastric Ulcer in Experimental Rats

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Abstract

The anti-ulcer activity of hydro alcoholic extract of Rhus coriaria Linn (HAERC) was investigated in Indomethacin and Water immersion-induced restraint gastric ulcer in Wistar rats. The assessment was carried out by using ulcer index, ulcer score and histopathological studies of the specimens. HAERC at doses of 145 and 248 mg/kg given orally produced significant inhibition of the gastric lesions induced by Indomethacin and Water Immersion restraint method and the results were comparable to the standard treatment regime. We observed that Rhus coriaria Linn extract exhibits significant anti ulcer activity and thus supports the Unani claims about the drug.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

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No ethics committee approval was required for this article type.

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Not applicable for this article.

How to Cite This Article

Haqeeq Ahmad. 2015. \u201cAnti-Ulcer Activity of Rhus Coriaria in Indomethacin and Water Immersion Restraint Induced Gastric Ulcer in Experimental Rats\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 14 (GJMR Volume 14 Issue B7): .

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GJMR Volume 14 Issue B7
Pg. 1- 7

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

indomethacin post sumaq rhus coriaria ulcer index water immersion induced ulcer model

Submission ReceivedDecember 16, 2013
Peer Review Double Blind
Handling Editor
Accepted January 1, 2014
Published January 15, 2014

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January 19, 2015

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Article Matrices

Total Score: 104

Country: India

Subject: Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine

Authors: Haqeeq Ahmad, Abdul Wadud, Nasreen Jahan, Izharul Hasan (PhD/Dr. count: 0)

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Publish Date: 2015 01, Mon

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Total Views: 4268

Total Downloads: 2160

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