Antimicrobial Properties of Jatropha curcas L. against Dental Pathogens

Ogechi O. Anyanwu
Ogechi O. Anyanwu
Peter M. Eze
Peter M. Eze
Nnaoma I.E
Nnaoma I.E
Kenneth G. Ngwoke
Kenneth G. Ngwoke
Nnamdi Azikiwe University Nnamdi Azikiwe University

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Antimicrobial Properties of Jatropha curcas L. against Dental Pathogens

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Abstract

This research is aimed at investigating the in vitro antimicrobial activities of Jatropha Curcas twigs against dental carries-causing bacteria. The methanol/methyl chloride crude extract of J. Curcas twigs was fractionated into aqueous, n-hexane, ethyl acetate, and butanol fractions. Using the agar well diffusion and the agar dilution methods, the antimicrobial activities of plant fractions were determined against strains of Streptococcus mutans isolated from dental swabs from patients with dental caries. The ethyl acetate fraction showed best antimicrobial activity with a minimum inhibitory concentration (MIC) of 6.25 mg/ml, followed by the butanol and n-hexane fractions, both with MICs ≥ 25 mg/ml against S. mutans . The aqueous fraction showed no activity against all strains of S. mutans tested. The result of our study reveals that J. Curcas twig possesses antimicrobial against dental caries-causing bacteria strains. This justifies the folkloric use of the plant twigs in oral hygiene as a chewing stick/toothbrush for the prevention of dental caries.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Ogechi O. Anyanwu. 2018. \u201cAntimicrobial Properties of Jatropha curcas L. against Dental Pathogens\u201d. Global Journal of Medical Research - J: Dentistry & Otolaryngology GJMR-J Volume 18 (GJMR Volume 18 Issue J2).

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-J Classification NLMC Code: WU 350
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v1.2

Issue date
October 5, 2018

Language
en
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Antimicrobial Properties of Jatropha curcas L. against Dental Pathogens

Ogechi O. Anyanwu
Ogechi O. Anyanwu <p>Nnamdi Azikiwe University</p>
Peter M. Eze
Peter M. Eze
Nnaoma I.E
Nnaoma I.E
Kenneth G. Ngwoke
Kenneth G. Ngwoke

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