Antioxidant Activity of Phenyl Alanine Mandelates by Chemical and Electrochemical Methods

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Usha S
Usha S
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Charles Kanakam Christopher
Charles Kanakam Christopher
α Anna University, Chennai Anna University, Chennai

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Antioxidant Activity of Phenyl Alanine Mandelates by Chemical and Electrochemical Methods

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Abstract

Food decomposition in human body due to the redox reactions results in the formation of reactive oxygen species (ROS). ROS obtained during metabolic activitities in our body are responsible for cancerous diseases. ROS are scavenged by hydroxyl radicals present in the small organic molecules. Novel small organic molecules like mandelic acid -amino acid complexes, possess the weak hydrogen bonds and vanderwaals forces of attractions in the complex formation results in the antioxidant property. The title compounds, Rphenyl alanine-Smandelate (RPASMA), Bis-L-phenyl alanine mandelate (BLPAMA) and L-phenyl alanine bis mandelate (BMALPA) are synthesised, carried out characterisation studies like FTIR, NMR, TG-DTA, mass, UV and melting point and grown single crystal by slow evaporation technique confirmed the structure by single crystal XRD. The electrochemical behaviour of the phenyl alanine mandelates show the existence of redox activity using cyclic voltammetry and is confirmed by comparing with the chemical behaviour using DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging method.

References

20 Cites in Article
  1. Jiri Jirisochor,Dobes,Branislav Olgakrystofova,Petr Ruttkaynedecky,Miroslav Babula,Tunde Pohanka,Ondrej Jurikova,Vojtech Zitka,Borivoj Adam,Rene Klejdus,Int (2013). Unknown Title.
  2. A Emad,Shalaby,M Sanaa,Shanab (2013). Unknown Title.
  3. Michael Antolovich,Paul Prenzler,Emilios Patsalides,Suzanne Mcdonald,Kevin Robards (2002). Methods for testing antioxidant activity.
  4. F Malki,A Tonati,K Hamza,S Moulay,M Baltas (2016). Unknown Title.
  5. Maria Matos,Francisco Mura,Saleta Vazquez-Rodriguez,Fernanda Borges,Lourdes Santana,Eugenio Uriarte,Claudio Olea-Azar (2015). Study of Coumarin-Resveratrol Hybrids as Potent Antioxidant Compounds.
  6. S Usha,Charles Christopher,Cst (2016). Unknown Title.
  7. Subramanian Usha,Charles Kanakam Christopher (2016). Impact of Crystal Parameters in XRD and DFT Measurements.
  8. W Brand-Williams,M Cuvelier,C Berset (1995). Use of a free radical method to evaluate antioxidant activity.
  9. Aurelia Magdalena Pisoschi,Carmen Cimpeanu,Gabriel Predoi (2015). Unknown Title.
  10. Turkoz A Ebru,Atiyue Car,Nuronar (2016). Unknown Title.
  11. Anna Masek,Ewa Chrzescijanska,Marian Zaborski (2014). Unknown Title.
  12. F Jesius,Mercedes Artega,Alberto Ruiz-Montoya,Gema Palma,Sara Alonso-Garrido,Jose Pintado,Rodriguez-Mellado (2012). Unknown Title.
  13. Aleksandra Simic,Dragon Manojlovic,Dejan Segan,Marija Todorovic (2007). Unknown Title.
  14. Elahesadaat Hosseini,Mohammad Rafiei,Mahta Mirzaei (2014). Unknown Title.
  15. Gunars Tirzitis,Grzegorz Bartosz (2010). Determination of antiradical and antioxidant activity: basic principles and new insights..
  16. Jose Teixeira,Alexandra Gaspar,E Garrido,Jorge Garrido,Fernanda Borges (2013). Unknown Title.
  17. Marijan Šeruga,Ivana Novak,Lidija Jakobek (2011). Determination of polyphenols content and antioxidant activity of some red wines by differential pulse voltammetry, HPLC and spectrophotometric methods.
  18. James Merichel Plaza,Charlotta Karinki,Turner (2014). Unknown Title.
  19. Rebecca Schmitt,R Molitor,Tsunghsueh Wu (2012). Unknown Title.
  20. G Ilias,Carlos Kirkinezos,Moraes (2001). Unknown Title.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Usha S. 2016. \u201cAntioxidant Activity of Phenyl Alanine Mandelates by Chemical and Electrochemical Methods\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 16 (GJMR Volume 16 Issue B1): .

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords
Classification
GJMR-B Classification: NLMC Code: QV 325
Version of record

v1.2

Issue date

May 31, 2016

Language
en
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Food decomposition in human body due to the redox reactions results in the formation of reactive oxygen species (ROS). ROS obtained during metabolic activitities in our body are responsible for cancerous diseases. ROS are scavenged by hydroxyl radicals present in the small organic molecules. Novel small organic molecules like mandelic acid -amino acid complexes, possess the weak hydrogen bonds and vanderwaals forces of attractions in the complex formation results in the antioxidant property. The title compounds, Rphenyl alanine-Smandelate (RPASMA), Bis-L-phenyl alanine mandelate (BLPAMA) and L-phenyl alanine bis mandelate (BMALPA) are synthesised, carried out characterisation studies like FTIR, NMR, TG-DTA, mass, UV and melting point and grown single crystal by slow evaporation technique confirmed the structure by single crystal XRD. The electrochemical behaviour of the phenyl alanine mandelates show the existence of redox activity using cyclic voltammetry and is confirmed by comparing with the chemical behaviour using DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging method.

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Antioxidant Activity of Phenyl Alanine Mandelates by Chemical and Electrochemical Methods

Usha S
Usha S Anna University, Chennai
Charles Kanakam Christopher
Charles Kanakam Christopher

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