Association between Necrotizing Sialometaplasia and Smoking: An Integrative Review

1
Lucas Gabriel Silva Ferreira
Lucas Gabriel Silva Ferreira
2
Rita de Cássia Silva de Oliveira
Rita de Cássia Silva de Oliveira
3
Leila Maués Oliveira Hanna
Leila Maués Oliveira Hanna
1 State University of Pará

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Necrotizing Sialometaplasia (NS) is a benign, self-limiting rare inflammatory condition that involves the salivary glands tissues and simulates a malignant process. The etiology of this lesion is still not fully understood. The aim of this study was observe and evaluate the profile of this condition and its association with smoking. This integrative review followed six methodological stages and evaluated only case reports published from 1973 to 2022. It was analyzed 134 cases which 25% of them were associated with smoking. Others clinical features were also observed and described. Although the NS is a rare condition, it is necessary to know and understand, so as not to confuse this lesion with a malignant neoplasm and apply inappropriate treatments that may impair the patient’s quality of life.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

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No ethics committee approval was required for this article type.

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Not applicable for this article.

Lucas Gabriel Silva Ferreira. 2026. \u201cAssociation between Necrotizing Sialometaplasia and Smoking: An Integrative Review\u201d. Global Journal of Medical Research - K: Interdisciplinary GJMR-K Volume 23 (GJMR Volume 23 Issue K2): .

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Neck and salivary gland cancer research review on nicotine's impact and salivary glands.
Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-K Classification: NLM: WU 140
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v1.2

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April 21, 2023

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English

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Necrotizing Sialometaplasia (NS) is a benign, self-limiting rare inflammatory condition that involves the salivary glands tissues and simulates a malignant process. The etiology of this lesion is still not fully understood. The aim of this study was observe and evaluate the profile of this condition and its association with smoking. This integrative review followed six methodological stages and evaluated only case reports published from 1973 to 2022. It was analyzed 134 cases which 25% of them were associated with smoking. Others clinical features were also observed and described. Although the NS is a rare condition, it is necessary to know and understand, so as not to confuse this lesion with a malignant neoplasm and apply inappropriate treatments that may impair the patient’s quality of life.

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Association between Necrotizing Sialometaplasia and Smoking: An Integrative Review

Lucas Gabriel Silva Ferreira
Lucas Gabriel Silva Ferreira State University of Pará
Rita de Cássia Silva de Oliveira
Rita de Cássia Silva de Oliveira
Leila Maués Oliveira Hanna
Leila Maués Oliveira Hanna

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