Association of Rs763780 Polymorphism of Gene IL17F with the Risk of Developing Rheumatoid Arthritis in Uzbekistan

1
Surayyo Z. Yuldasheva
Surayyo Z. Yuldasheva
2
M. Sh. Karimov
M. Sh. Karimov
3
A. A. Eshmurzaeva
A. A. Eshmurzaeva
4
Kh. M. Marufkhanov
Kh. M. Marufkhanov
5
M. V. Sibirkina
M. V. Sibirkina

Send Message

To: Author

GJMR Volume 21 Issue H2

Article Fingerprint

ReserarchID

FQKH8

Association of Rs763780 Polymorphism of Gene IL17F with the Risk of Developing Rheumatoid Arthritis in Uzbekistan Banner
  • English
  • Afrikaans
  • Albanian
  • Amharic
  • Arabic
  • Armenian
  • Azerbaijani
  • Basque
  • Belarusian
  • Bengali
  • Bosnian
  • Bulgarian
  • Catalan
  • Cebuano
  • Chichewa
  • Chinese (Simplified)
  • Chinese (Traditional)
  • Corsican
  • Croatian
  • Czech
  • Danish
  • Dutch
  • Esperanto
  • Estonian
  • Filipino
  • Finnish
  • French
  • Frisian
  • Galician
  • Georgian
  • German
  • Greek
  • Gujarati
  • Haitian Creole
  • Hausa
  • Hawaiian
  • Hebrew
  • Hindi
  • Hmong
  • Hungarian
  • Icelandic
  • Igbo
  • Indonesian
  • Irish
  • Italian
  • Japanese
  • Javanese
  • Kannada
  • Kazakh
  • Khmer
  • Korean
  • Kurdish (Kurmanji)
  • Kyrgyz
  • Lao
  • Latin
  • Latvian
  • Lithuanian
  • Luxembourgish
  • Macedonian
  • Malagasy
  • Malay
  • Malayalam
  • Maltese
  • Maori
  • Marathi
  • Mongolian
  • Myanmar (Burmese)
  • Nepali
  • Norwegian
  • Pashto
  • Persian
  • Polish
  • Portuguese
  • Punjabi
  • Romanian
  • Russian
  • Samoan
  • Scots Gaelic
  • Serbian
  • Sesotho
  • Shona
  • Sindhi
  • Sinhala
  • Slovak
  • Slovenian
  • Somali
  • Spanish
  • Sundanese
  • Swahili
  • Swedish
  • Tajik
  • Tamil
  • Telugu
  • Thai
  • Turkish
  • Ukrainian
  • Urdu
  • Uzbek
  • Vietnamese
  • Welsh
  • Xhosa
  • Yiddish
  • Yoruba
  • Zulu

As a result of the study conducted, it was witnessed that the G allele and the heterozygous A / G genotype of the IL17F gene (rs763780) among patients with RA are significantly higher than in the control group. In particular, the most significant discrepancies were registered in patients with articular-visceral form of the disease whom the G allele exceeded the proportion of carriage in the control statistically significantly 2.58 times (χ2 = 4.512; P = 0.037; OR = 2.58; 95% CI: 1.076 -6.188). On the part of the heterozygous genotype A / G there was a clear tendency to increase its frequency by more than twice (χ2 = 2.011; P = 0.165; OR = 2.068; 95% CI: 0758-5.645) which in turn indicates the possible participation of the studied polymorphism in the pathogenesis of RA.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

Surayyo Z. Yuldasheva. 2021. \u201cAssociation of Rs763780 Polymorphism of Gene IL17F with the Risk of Developing Rheumatoid Arthritis in Uzbekistan\u201d. Global Journal of Medical Research - H: Orthopedic & Musculoskeletal System GJMR-H Volume 21 (GJMR Volume 21 Issue H2): .

Download Citation

An analysis of genes R763780 and IL17 in OA patients.
Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords
Classification
GJMR-H Classification: NLMC Code: WE 346
Version of record

v1.2

Issue date

September 15, 2021

Language

English

Experiance in AR

The methods for personal identification and authentication are no exception.

Read in 3D

The methods for personal identification and authentication are no exception.

Article Matrices
Total Views: 1972
Total Downloads: 1012
2026 Trends
Research Identity (RIN)
Related Research

Published Article

As a result of the study conducted, it was witnessed that the G allele and the heterozygous A / G genotype of the IL17F gene (rs763780) among patients with RA are significantly higher than in the control group. In particular, the most significant discrepancies were registered in patients with articular-visceral form of the disease whom the G allele exceeded the proportion of carriage in the control statistically significantly 2.58 times (χ2 = 4.512; P = 0.037; OR = 2.58; 95% CI: 1.076 -6.188). On the part of the heterozygous genotype A / G there was a clear tendency to increase its frequency by more than twice (χ2 = 2.011; P = 0.165; OR = 2.068; 95% CI: 0758-5.645) which in turn indicates the possible participation of the studied polymorphism in the pathogenesis of RA.

Our website is actively being updated, and changes may occur frequently. Please clear your browser cache if needed. For feedback or error reporting, please email [email protected]
×

This Page is Under Development

We are currently updating this article page for a better experience.

Request Access

Please fill out the form below to request access to this research paper. Your request will be reviewed by the editorial or author team.
X

Quote and Order Details

Contact Person

Invoice Address

Notes or Comments

This is the heading

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.

High-quality academic research articles on global topics and journals.

Association of Rs763780 Polymorphism of Gene IL17F with the Risk of Developing Rheumatoid Arthritis in Uzbekistan

M. Sh. Karimov
M. Sh. Karimov
A. A. Eshmurzaeva
A. A. Eshmurzaeva
Kh. M. Marufkhanov
Kh. M. Marufkhanov
M. V. Sibirkina
M. V. Sibirkina

Research Journals