Bacteriological Profile and Antibiotic Susceptibility Pattern of Blood Culture Isolates from Patients Visiting Janamaitri Hospital, Balaju, Kathmandu, Nepal

Bacteriological Profile and Antibiotic Susceptibility Pattern of Blood Culture Isolates from Patients Visiting Janamaitri Hospital, Balaju, Kathmandu, Nepal

Surya Subedi

Contact

Prakash Simkhada Lecturer

Contact

Shiva Raj K. C.

Contact

Santosh Lamichhane

Contact

Upendra Thapa Shrestha

Contact

Tribhuvan University

Article Fingerprint

ReserarchID

64ZAH

AI TAKEAWAY

Connecting with the Eternal Ground

Abstract

Bacterial blood stream infections can lead to life threatening sepsis that requires rapid antimicrobial treatment otherwise may lead to morbidity and mortality of patients. Blood culture is gold standard technique which provides essential information for the diagnosis and appropriate medication to save life of affected patients. Present study was conducted to determine the bacteriological profile of blood stream infections and their antibiotic susceptibility pattern in patients visiting Janamaitri Hospital, Balaju, Kathmandu, Nepal. A total of 838 blood samples were collected from the clinically suspected cases of bacteremia and septicaemia. Isolates were identified by standard biochemical tests, and antibiotic susceptibility test was performed by using CLSI guidelines. Positive blood culture was obtained in 61/838 (7.28%) where gram negative accounted for 48/61 (78.69%) in which Salmonella Paratyphi A was leading organisms and gram positive accounted for 13/61(21.31%) in which Staphylococcus aureus was leading organisms.

References

25 Cites in Article

Reference Format

S Trevino,D Ross (2007). Bacterermia and Sepsis.
T Zenebe,S Kannan,D Yilma,G Beyene (2011). Invasive Bacterial Pathogens and their Antibiotic Susceptibility Patterns in Jimma University Specialized Hospital, Jimma, Southwest Ethiopia.
J William,Max (1998). Bacteremia, septicemia and endocarditis.
M Cheesbrough (2006). District Laboratory practice in tropical countries.
P Murray,K Rosenthal,M Pfaller (2013). Medical Microbiology seventh edition Saunders.
S Garg,Anupurba,Garg (2007). Bacteriological profile and antimicrobial resistance of blood culture isolates from a university hospital.
Surya Subedi,Mahesh Chaudhary,Bidya Shrestha (2016). High MDR and ESBL Producing Escherichia coli and Klesbiella pneumoniae from Urine, Pus and Sputum Samples.
J Collee,J Duguid,A Fraser,B Marmion,A Simmons (2006). Laboratory strategies in the diagnosis of infective syndromes.
K Gohel,A Jojera,S Soni,S Gang,R Sabnis,M Desai (2014). Bacteriological profile and drug resistance patterns of blood culture isolates in a tertiary care nephrourology teaching institute.
J Collee,Mackie (1996). Mackie and McCartney Practical Medical Microbiology, 14th edition.
(2012). Clinical Laboratory Standard Institute Performance Standards for Antimicrobial Susceptibility Testing; Twenty-second Informational Supplement.
A Magiorakos,A Srinivasan,R Carey,Y Carmeli,M Falagas (2012). Multidrug resistance, extensively drug resistance and pandrug-resistance bacteria: An international expert proposal for interim standard definitions for acquired resistance.
D Sham,C Thomsberry,D Mayfield,M Jones,J Karlowsky (2001). Multidrug resistant urinary tract isolates of Escherichia coli: Prevalence and patient demographics in United States in 2000.
(2010). An Overview of the Clinical and Laboratory Standards Institute (CLSI) and Its Impact on Antimicrobial Susceptibility Tests.
A Magiorakos,A Srinivasan,R Carey,Y Carmeli,M Falagas,C Giske,J Harbarth,G Kahlmeter,B Olsson-Liljequist,D Paterson,L Rice,M Struelens,A Vatopoulos,J Weber,D Monnet (2012). Multidrug-resistant, extensively drug-resistant and pandrugresistant bacteria: an international expert proposal for interim standard definitions for acquired resistance.
J Burke (1999). Editorial Board.
G Larry,L Michael,P Melvin (1997). Update on Detection of Bacteremia and Fungemia.
S Subedi,J Maharjan,B Shrestha (2016). Antibiotic susceptibility test of Klebsiella pneumoniae and K. oxytoca isolated from different clinical samples and perform random amplified polymorphic DNA among K. pneumoniae.
Shubana Karki,Ganesh Rai,Rekha Manandhar (2010). Bacteriological Analysis and Antibiotic Sensitivity Pattern of Blood Culture Isolates in Kanti Children Hospital.
P Bhandari,S Manandhar,B Shrestha,N Dulal (2016). Etiology of bloodstream infection and antibiotic susceptibility pattern of the isolates.
M Kante,P Uma,John Ms,M Naidu (2014). Bacterial profile of blood stream infections and antibiotic susceptibility pattern of isolates.
A Magiorakos,A Srinivasan,R Carey,Y Carmeli,M Falagas (2012). Multidrug resistance, extensively drug resistance and pandrug-resistance bacteria: An international expert proposal for interim standard definations for acquired resistance.
A Labi,N Obeng-Nkrumah,Addison No,E Donkor (2014). Salmonella blood stream infections in a tertiary care setting in Ghana.
N Sharma,R Koju,B Karmacharya,M Tamang,R Makaju,N Nepali (2004). Typhoid fever in Dhulikhel hospital, Nepal.
Dharm Bhatta,Abhishek Gaur,H Supram (2013). Bacteriological profile of blood stream infections among febrile patients attending a tertiary care centre of Western Nepal.

Download References

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Surya Subedi. 2016. \u201cBacteriological Profile and Antibiotic Susceptibility Pattern of Blood Culture Isolates from Patients Visiting Janamaitri Hospital, Balaju, Kathmandu, Nepal\u201d. Global Journal of Medical Research - C: Microbiology & Pathology GJMR-C Volume 16 (GJMR Volume 16 Issue C1): .

More Citation Formats

Select Citation Style:

Download Citation

Download Article

GJMR Volume 16 Issue C1
Pg. 25- 31

Explore Journals Explore Volume Read This Issue

Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

Not Found

Classification

GJMR-C Classification: NLMC Code: QW 4, QW 50

Submission ReceivedDecember 8, 2015
Peer Review Double Blind
Handling Editor
Accepted January 4, 2016
Published January 15, 2016

Version of record

v1.2

Issue date

May 10, 2016

Language

Experiance in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

View in VR

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

View in 3D

Article Matrices

Total Score: 105

Country: Nepal

Subject: Global Journal of Medical Research - C: Microbiology & Pathology

Authors: Prakash Simkhada, Shiva Raj K. C., Santosh Lamichhane, Surya Subedi, Upendra Thapa Shrestha (PhD/Dr. count: 0)

View Count (all-time): 143

Total Views (Real + Logic): 3663

Total Downloads (simulated): 1838

Publish Date: 2016 05, Tue

Monthly Totals (Real + Logic):

Month 1: 46 views
Month 2: 57 views
Month 3: 62 views
Month 4: 33 views
Month 5: 33 views
Month 6: 48 views
Month 7: 41 views
Month 8: 31 views
Month 9: 45 views
Month 10: 37 views
Month 11: 26 views
Month 12: 25 views
Month 13: 14 views
Month 14: 30 views
Month 15: 28 views
Month 16: 15 views
Month 17: 24 views
Month 18: 21 views
Month 19: 49 views
Month 20: 33 views
Month 21: 26 views
Month 22: 33 views
Month 23: 15 views
Month 24: 27 views
Month 25: 19 views
Month 26: 25 views
Month 27: 19 views
Month 28: 26 views
Month 29: 28 views
Month 30: 42 views
Month 31: 32 views
Month 32: 38 views
Month 33: 23 views
Month 34: 32 views
Month 35: 22 views
Month 36: 17 views
Month 37: 22 views
Month 38: 28 views
Month 39: 30 views
Month 40: 26 views
Month 41: 22 views
Month 42: 48 views
Month 43: 24 views
Month 44: 29 views
Month 45: 41 views
Month 46: 24 views
Month 47: 37 views
Month 48: 15 views
Month 49: 22 views
Month 50: 17 views
Month 51: 35 views
Month 52: 35 views
Month 53: 36 views
Month 54: 28 views
Month 55: 16 views
Month 56: 48 views
Month 57: 19 views
Month 58: 23 views
Month 59: 48 views
Month 60: 29 views
Month 61: 27 views
Month 62: 39 views
Month 63: 38 views
Month 64: 23 views
Month 65: 25 views
Month 66: 22 views
Month 67: 28 views
Month 68: 25 views
Month 69: 24 views
Month 70: 11 views
Month 71: 11 views
Month 72: 27 views
Month 73: 19 views
Month 74: 33 views
Month 75: 21 views
Month 76: 25 views
Month 77: 27 views
Month 78: 41 views
Month 79: 22 views
Month 80: 17 views
Month 81: 30 views
Month 82: 45 views
Month 83: 34 views
Month 84: 28 views
Month 85: 36 views
Month 86: 18 views
Month 87: 24 views
Month 88: 29 views
Month 89: 28 views
Month 90: 40 views
Month 91: 26 views
Month 92: 29 views
Month 93: 32 views
Month 94: 26 views
Month 95: 25 views
Month 96: 37 views
Month 97: 33 views
Month 98: 27 views
Month 99: 33 views
Month 100: 10 views
Month 101: 27 views
Month 102: 37 views
Month 103: 46 views
Month 104: 23 views
Month 105: 27 views
Month 106: 31 views
Month 107: 19 views
Month 108: 29 views
Month 109: 29 views
Month 110: 32 views
Month 111: 32 views
Month 112: 35 views
Month 113: 30 views
Month 114: 28 views
Month 115: 34 views
Month 116: 27 views
Month 117: 31 views
Month 118: 53 views
Month 119: 24 views
Month 120: 33 views

Total Views: 3663

Total Downloads: 1838

2026 Trends

Published Article

Our website is actively being updated, and changes may occur frequently. Please clear your browser cache if needed. For feedback or error reporting, please email [email protected]