Biochemical Aspects of Preclinical Prediction of the Severity of the Knee Joint Injuries in Acute Period

Bekhzod Abdullaev; Murod Karimov; Feruza Inoyatova; Umid Kholmurodov; Kirill Tolochko

Biochemical Aspects of Preclinical Prediction of the Severity of the Knee Joint Injuries in Acute Period

Bekhzod Abdullaev * §

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Murod Karimov

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Feruza Inoyatova

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Umid Kholmurodov

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Kirill Tolochko

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§ Tashkent Medical Academy

Biochemical Aspects of Preclinical Prediction of the Severity of the Knee Joint Injuries in Acute Period

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Abstract

Early detection of markers of joint damage in order to predict the course of the inflammatory process and the risk of developing post-traumatic osteoarthritis is one of the urgent problems of traumatology and orthopedics. Determining the molecules of average mass and necrotic substances in the hemosynovial fluid of the injured knee joint demonstrates a significant association with the severity of the injury, the severity of the inflammatory process and the progression of post-traumatic osteoarthritis. Increasing the level of necrotic substances in hemosynovial fluid to 1.6-2.0 U/ml, 45.4% corresponds to significant damage to the intra-articular structures and leads to the development of the inflammatory process; an increase in excess of 2.0 U/ml is an indicator of severe joint injury and leads to a complicated postoperative course.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

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How to Cite This Article

Bekhzod Abdullaev, Murod Karimov, Feruza Inoyatova, Umid Kholmurodov, Kirill Tolochko. 2019. "Biochemical Aspects of Preclinical Prediction of the Severity of the Knee Joint Injuries in Acute Period". Global Journal of Medical Research - H: Orthopedic & Musculoskeletal System GJMR-H Volume 19 (GJMR Volume 19 Issue H1).

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Journal Specifications

Crossref Journal DOI 10.17406/gjmr

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-H Classification NLMC Code: WE 348

Submission ReceivedDecember 15, 2018
Peer Review Double Blind
Handling Editor
Accepted January 5, 2019
Published January 15, 2019

Version of record

v1.2

Issue date

February 12, 2019

Language

English

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Article Matrices

Total Score: 145

Country: Uzbekistan

Subject: Global Journal of Medical Research

Authors: Bekhzod Abdullaev, Murod Karimov, Feruza Inoyatova, Umid Kholmurodov, Kirill Tolochko (PhD/Dr. count: 0)

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