Biochemical Changes of Mancozeb-Induced AlteBiochemical Changes of Mancozeb-Induced Alternations in Testes and Thyroid gland of Male Ratsrnations in Testes and Thyroid gland of Male Rats

1
Ahmed Abdelrafea
Ahmed Abdelrafea
2
Prof. Hesham Zaki Ibrahim
Prof. Hesham Zaki Ibrahim
3
Prof. Sabah Gaber El –Banna
Prof. Sabah Gaber El –Banna

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Mancozeb manganese ethylene bis dithiocarbamate polymeric complex -with zinc salts is a very important protective non-systemic fungicide, classified as an ethylene bis dithiocarbamate fungicide. Mancozeb used for controlling fungal diseases for a wide variety of crops because of its broad-spectrum as fungicidal effects and high compatibility with agrochemicals. The objective of this study was to investigate the results of the fungicide mancozeb at different doses on some biochemical parameters, reproductive performance, and histological changes in testes and thyroid gland. The low amount equals 1/7 of LD 50 manczeb-d 1 , and the high amount equals 1/3.5 of LD 50 mancozeb-d 1 . Amounts of mancozeb (mancozeb-d1 and mancozeb-d 2 ) adjusted according to the rat’s body weights. The results showed that mancozeb decreased plasma testosterone level, sperm count, viability, motility, and significantly (P

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No external funding was declared for this work.

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The authors declare no conflict of interest.

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Ahmed Abdelrafea. 2026. \u201cBiochemical Changes of Mancozeb-Induced AlteBiochemical Changes of Mancozeb-Induced Alternations in Testes and Thyroid gland of Male Ratsrnations in Testes and Thyroid gland of Male Rats\u201d. Global Journal of Medical Research - L: Nutrition GJMR-L Volume 22 (GJMR Volume 22 Issue L1): .

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Mice blood test results show biochemical alterations due to thyroid gland damage from MRL rats.
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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-L Classification: DDC Code: 612.44 LCC Code: QP188.T54
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v1.2

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July 9, 2022

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English

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Mancozeb manganese ethylene bis dithiocarbamate polymeric complex -with zinc salts is a very important protective non-systemic fungicide, classified as an ethylene bis dithiocarbamate fungicide. Mancozeb used for controlling fungal diseases for a wide variety of crops because of its broad-spectrum as fungicidal effects and high compatibility with agrochemicals. The objective of this study was to investigate the results of the fungicide mancozeb at different doses on some biochemical parameters, reproductive performance, and histological changes in testes and thyroid gland. The low amount equals 1/7 of LD 50 manczeb-d 1 , and the high amount equals 1/3.5 of LD 50 mancozeb-d 1 . Amounts of mancozeb (mancozeb-d1 and mancozeb-d 2 ) adjusted according to the rat’s body weights. The results showed that mancozeb decreased plasma testosterone level, sperm count, viability, motility, and significantly (P

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Biochemical Changes of Mancozeb-Induced AlteBiochemical Changes of Mancozeb-Induced Alternations in Testes and Thyroid gland of Male Ratsrnations in Testes and Thyroid gland of Male Rats

Ahmed Abdelrafea
Ahmed Abdelrafea
Prof. Hesham Zaki Ibrahim
Prof. Hesham Zaki Ibrahim
Prof. Sabah Gaber El –Banna
Prof. Sabah Gaber El –Banna

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