Characterization of Extract of P.Notatumisolated from Virgin Forest

Characterization of Extract of P.Notatumisolated from Virgin Forest

Adewole Ezekiel

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Idris O. O.

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Olajuyigbe A.B

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Afe Babalola University

Characterization of Extract of P.Notatumisolated from Virgin Forest

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Abstract

Penicillium notatum has been found years ago to be one of the leading novel candidates of fungi for the discovery of novel antibiotics. The fungus was isolated from eighty years old virgin forest Ikota, Ondo state. The fraction was obtained through column chromatography using mixture of solvents, after culturing and purification process of the extract. The fraction was characterized using gas chromatography mass spectrophotometer, the Gc-Ms results revealed Benzene, 1,2,4,5-trimethyl-having retention time 5.117,% of total 6.505%, pcymene having retention time 5.170 minutes, % of total 16.439%, Trans-Decalin, 2 methyl with retention time 5.235 minutes and % of total 9.468 %, also n-Nonadecanol-1 having retention time 5.301 minutes and 13.302 %, Naphthalene with retention time 6.161 minutes, % of total 11.369 %, 5, 8,11,14-Eicosatetraenoic acid, methyl ester, having retention time of 6.381 minutes and % of total 2.544 %. Literature reports had indicated the physiological activities of these compounds and of interest p-cymene and Naphthalene derivative to possess strong pharmaceutical uses.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

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Not applicable for this article.

How to Cite This Article

Adewole Ezekiel. 2015. \u201cCharacterization of Extract of P.Notatumisolated from Virgin Forest\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 15 (GJMR Volume 15 Issue B4): .

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GJMR Volume 15 Issue B4
Pg. 5- 20

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-B Classification: NLMC Code: QV 252

Submission ReceivedApril 12, 2015
Peer Review Double Blind
Handling Editor
Accepted May 2, 2015
Published May 15, 2015

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v1.2

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October 5, 2015

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Article Matrices

Total Score: 103

Country: Nigeria

Subject: Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine

Authors: Adewole Ezekiel, Idris O. O., Olajuyigbe A.B (PhD/Dr. count: 0)

View Count (all-time): 193

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Total Downloads (simulated): 2046

Publish Date: 2015 10, Mon

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Total Views: 4168

Total Downloads: 2046

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