Characterization of Hippocampus in Epileptic Sudanese Children using MRI

§ Sudan University of Science and Technology/college o...
‡ Gezira University- MRI Diagnostic center, Khartoum –...

Send Message

To: Author

Characterization of Hippocampus in Epileptic Sudanese Children using MRI

Article Fingerprint

ReserarchID

8VGLO

Characterization of Hippocampus in Epileptic Sudanese Children using MRI Banner

Key Research Insights

Synthesized scholarly intelligence & interactive research assistant
  • English
  • Afrikaans
  • Albanian
  • Amharic
  • Arabic
  • Armenian
  • Azerbaijani
  • Basque
  • Belarusian
  • Bengali
  • Bosnian
  • Bulgarian
  • Catalan
  • Cebuano
  • Chichewa
  • Chinese (Simplified)
  • Chinese (Traditional)
  • Corsican
  • Croatian
  • Czech
  • Danish
  • Dutch
  • Esperanto
  • Estonian
  • Filipino
  • Finnish
  • French
  • Frisian
  • Galician
  • Georgian
  • German
  • Greek
  • Gujarati
  • Haitian Creole
  • Hausa
  • Hawaiian
  • Hebrew
  • Hindi
  • Hmong
  • Hungarian
  • Icelandic
  • Igbo
  • Indonesian
  • Irish
  • Italian
  • Japanese
  • Javanese
  • Kannada
  • Kazakh
  • Khmer
  • Korean
  • Kurdish (Kurmanji)
  • Kyrgyz
  • Lao
  • Latin
  • Latvian
  • Lithuanian
  • Luxembourgish
  • Macedonian
  • Malagasy
  • Malay
  • Malayalam
  • Maltese
  • Maori
  • Marathi
  • Mongolian
  • Myanmar (Burmese)
  • Nepali
  • Norwegian
  • Pashto
  • Persian
  • Polish
  • Portuguese
  • Punjabi
  • Romanian
  • Russian
  • Samoan
  • Scots Gaelic
  • Serbian
  • Sesotho
  • Shona
  • Sindhi
  • Sinhala
  • Slovak
  • Slovenian
  • Somali
  • Spanish
  • Sundanese
  • Swahili
  • Swedish
  • Tajik
  • Tamil
  • Telugu
  • Thai
  • Turkish
  • Ukrainian
  • Urdu
  • Uzbek
  • Vietnamese
  • Welsh
  • Xhosa
  • Yiddish
  • Yoruba
  • Zulu
Reading Preferences
Font Size
Line Spacing
Background
This converted HTML version may contain rendering inconsistencies. Please refer to the PDF for the authoritative version, or click here to provide feedback.

Abstract

Seizures are the most noticeable clinical manifestations of epilepsy; measurement of the hippocampus on magnetic resonance (MR) images of the brain has been useful for the assessment of patients with seizures. Therefore this study aimed to diagnose subjects who had developed epilepsy by measuring the RT and LT hippocampus area and volume considering epilepsy duration, seizure frequency, EEG results, T2 signal intensity, treatment, and children ages as well as to correlate the MRI findings with EEG findings. This Study was conducted at Gezira University- MRI Diagnostic center –Khartoum –Sudan during the period from 2010up to2011using Siemens 0.5 Tesla MRI machine. A total of 29 Sudanese children of both genders with clinical history of generalized seizures, and 17 normal children who were selected as control group at different ages were involved in this study. Children with head injury or organic lesion found on MR images were excluded. The hippocampus was characterized in the coronal MR images; the area and volume of the right and Left sides were found to be reduces significantly in the diseased sample comparing with the control group; there was relationship between patient’s age and seizure duration and frequency as well as hippocampus area and volume. Significant differences were detected in the hippocampus area and volume in children who have got treatment and none treated children.T2 weighted images showed hyper signal intensity in the hippocampuses of the diseased sample. No significant differences were detected in males and females measurements. EEG failed in diagnoses of 12 (41.4%) cases of the sample, and new formulas were established for prediction of EEG findings regarding the hippocampus area and epilepsy duration.MRI has a great value in characterization hippocampus in epileptic Sudanese children.

References

20 Cites in Article
  1. 1. American Radiology (2011). ACR Appropriateness Criteria: Seizures and Epilepsy.
  2. 2. M. Ashtari,W. Barr,N. Schawl,B. Bogerts (1991). Threedimensional fast Low angle shot imaging and computerized volume measurement Of the hippocampus in patients with chronic epilepsy of the temporal Lobe. Am J Neuroradiol, 12, 941-947.
  3. 3. Poonam Banerjee,David Filippi,W. Allen Hauser (2009). The descriptive epidemiology of epilepsy-a review Epilepsy Res. Epilepsy Research, 85(1), 31-45.
  4. 4. R. Bronen,G. Cheung,J. Charles (1991). Imaging findings in Hippocampal sclerosis: correlation with pathology. Am J Neuroradiol, 12, 933-940.
  5. 5. Douglas Crompton,Ingrid Scheffer,Isabella Taylor,Mark Cook,Penelope McKelvie,Danya Vears,Kate Lawrence,Jacinta McMahon,Bronwyn Grinton,A. McIntosh,S. Berkovic Crompton,Ingrid E Scheffer,Isabella Taylor,Mark J Cook,Penelope A McKelvie,Danya F Vears,Kate M Lawrence,Jacinta M McMahon, Bronwyn E Grinton,Anne M McIntosh Samuel F Familial mesial temporal lobe epilepsy: a benign epilepsy syndrome showing complex inheritance Berkovic, Oxford Journals. Brain, 133(11), 3221-3231.
  6. 6. John Duncan (2010). Imaging in the surgical treatment of epilepsy. Nat Rev Neurol, 6(10), 537-550.
  7. 7. Fisher RS,van W (2005). Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE) Epilepsia. Epilepsia, 46(4), 470-472.
  8. 8. Geuze E,Vermetten E,de CS,Hijman R (2009). Neuropsychological performance is related to current social and occupational functioning in veterans with posttraumatic stress disorder. Depression and Anxiety, 26(1), 7-15.
  9. 9. Hesdorffer DC,Logroscino G,Benn EK (2011). Estimating risk for developing epilepsy: a populationbased study in Rochester, Minnesota Neurology. Neurology, 76, 23-27.
  10. 10. Jack CR,Sharborough FW,Twomey CK (1990). Temporal lobe seizures: lateralization with MR volume measurements of the hippocampal formation. Radiology, 175(2), 423-429.
  11. 11. G. Jackson,S. Berkovic,B. Tress,R. Kalnins,Gca Fabinyi,P. Bladin (1990). Hippocampal sclerosis can be reliably detected by magnetic resonance imaging. Neurology, 40, 1869-1875.
  12. 12. Jullie Pan,Anne Williamson,Idil Cavus,Hoby Hetherington,Hitten Zaveri,Ognen Petroff,Dennis Spencer (2008). Neurometabolism in human epilepsy. Epilepsia, 49(0 3), 31-41.
  13. 13. Kuzniecky R,de V,Ethier R (1987). Magnetic resonance imaging in temporal lobe epilepsy: Pathological correlations. Annals of Neurology, 22(3), 341-347.
  14. 14. Luiz a,Susana a,I´scia b,Li Li,Marilisa a,Carlos a,Fernando a,a. Epilepsy (2006). Fernando Cendes a, MRI volumetry shows increased anterior thalamic volumes in patients with absence seizures.
  15. 15. (2012). Margerison1 J. H. , Corsfllts, J. A. N. Epilepsy And The Temporal Lobes A Clinical, Electroencephalographic And Neuropathological Study Of The Brain In Epilepsy. Brain
  16. 16. Noe KH (2011). Seizures: diagnosis and management in the outpatient setting Semin Neurol.
  17. 17. (2011). Brain basics. Brain basics
  18. 18. D. Porpura,O. Gonzalez-Monteagudo (1960). Neuropath, exp. Neurol,19,421, 19, 421.
  19. 19. Yoichi Ryota Serino,Masayoshi Mai Hanamiya,epilepsy (2009). Autonomic Neuroscience. Autonomic Neuroscience, 148
  20. 20. Andrew Wilner,Selim Benbadis (2010). Epilepsy therapy in 2010 Therapy. Therapy, 7(5), 445-448.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Caroline Edward Ayad, Mohammed Abdalla Bashir Abdalla, Mohammed .E.M. Garelnabi, Elsafi Ahmed Abdalla. 2026. "Characterization of Hippocampus in Epileptic Sudanese Children using MRI". Global Journal of Medical Research - D: Radiology, Diagnostic GJMR-D Volume 13 (GJMR Volume 13 Issue 32 (D3)).

More Citation Formats

Download Citation

Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords
Classification
GJMR-D Classification NLMC Code: WS 141
WN 180
Version of record

v1.2

Issue date
December 4, 2013

Language
English
Order Article Reprint
Experience in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

Article Matrices
Total Views: 7.4K
Total Downloads: 330
All Trends

Request Access

Please fill out the form below to request access to this research paper. Your request will be reviewed by the editorial or author team.
X

This is the heading

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.

High-quality academic research articles on global topics and journals.

Characterization of Hippocampus in Epileptic Sudanese Children using MRI

Caroline Ayad
Caroline Ayad
Mohammed Abdalla
Mohammed Abdalla
Mohammed Garelnabi
Mohammed Garelnabi
Elsafi Abdalla
Elsafi Abdalla