Chronic Ill Effects of Air Pollution in Children: Neurological Derailment

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Chronic Ill Effects of Air Pollution in Children:  Neurological Derailment

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Abstract

Exposure to complex mixtures of air pollutants produces inflammation in the upper and lower respiratory tract. Because the nasal cavity is a common portal of entry, respiratory and olfactory epithelia are vulnerable targets for toxicological damage. The brain is a target for several environmental substances that may or may not be primarily airborne. Neurodevelopment and neuro-behaviour largely reflect brain development and its chemically induced modification, with resulting delays or deficits in development. It is generally believed that the developing brain is a particularly vulnerable target for chemical insult, and that such insult may have long lasting or even irreversible developmental consequences. Environmental exposures in uterus and during early life may permanently change the body’s structure, physiology and metabolism, and lead to diseases in adult life. Infants are particularly vulnerable because of their rapid growth and cell differentiation, immaturity of metabolic pathways and development of vital organ systems. The central nervous system has unprotected barriers and a broad time window of conformation, leading to a long period of vulnerability in the developmental process and to susceptibility to any environmental insult leading to neurological diseases.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Dr. Anita Sharma, Dr. Harendra Kumar. 1970. "Chronic Ill Effects of Air Pollution in Children: Neurological Derailment". Global Journal of Human-Social Science - B: Geography, Environmental Science & Disaster Management GJHSS-B Volume 12 (GJHSS Volume 12 Issue B6).

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Crossref Journal DOI 10.17406/GJHSS

Print ISSN 0975-587X

e-ISSN 2249-460X

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Chronic Ill Effects of Air Pollution in Children: Neurological Derailment

Dr. Sharma
Dr. Sharma Moradabad Institute of Technology
Dr. Kumar
Dr. Kumar