Circulating Progesterone Levels and Ongoing Pregnancy Rates in Controlled Ovarian Stimulation Cycles in Assisted Reproduction Techniques

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Shailja Verma
Shailja Verma
2
Pratap Kumar
Pratap Kumar
1 Kingston Hospital, NHS, London, UK

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How can we prevent premature leutinization in our IVF cycles? To help find the solution a study designed with specific exclusion criteria in an assisted reproductive centre of a tertiary care hospital was designed. In a period of 2 years 100 patients were followed up prospectively. GnRH antagonist protocol was implemented for all recruits because of shorter duration of treatment and as it prevented hyperstimulation. Specific criteria was chosen for GnRH anatagonist initiation. Serum Progesterone measurements were used to predict premature leutinization. Electro-chemiluminiscence Immunoassay using COBAS 6000 used for the measurements. Three different groups analysed in above cohort and we concluded that despite of progesterone rise pregnancy outcome was unaffected. Why is the question answered in discussion.

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No external funding was declared for this work.

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The authors declare no conflict of interest.

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No ethics committee approval was required for this article type.

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Not applicable for this article.

Shailja Verma. 2017. \u201cCirculating Progesterone Levels and Ongoing Pregnancy Rates in Controlled Ovarian Stimulation Cycles in Assisted Reproduction Techniques\u201d. Global Journal of Medical Research - E: Gynecology & Obstetrics GJMR-E Volume 17 (GJMR Volume 17 Issue E1): .

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-E Classification: NLMC Code: WJ 190
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June 23, 2017

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How can we prevent premature leutinization in our IVF cycles? To help find the solution a study designed with specific exclusion criteria in an assisted reproductive centre of a tertiary care hospital was designed. In a period of 2 years 100 patients were followed up prospectively. GnRH antagonist protocol was implemented for all recruits because of shorter duration of treatment and as it prevented hyperstimulation. Specific criteria was chosen for GnRH anatagonist initiation. Serum Progesterone measurements were used to predict premature leutinization. Electro-chemiluminiscence Immunoassay using COBAS 6000 used for the measurements. Three different groups analysed in above cohort and we concluded that despite of progesterone rise pregnancy outcome was unaffected. Why is the question answered in discussion.

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Circulating Progesterone Levels and Ongoing Pregnancy Rates in Controlled Ovarian Stimulation Cycles in Assisted Reproduction Techniques

Shailja Verma
Shailja Verma Kingston Hospital, NHS, London, UK
Pratap Kumar
Pratap Kumar

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