Clinico Haematological study of Acute Lymphoblastic Leukemia
Context: Acute Lymphoblastic leukemia encom-passes a group of neoplasms composed of immature, precursor B (pre- B) or T (pre-T) lymphocytes referred to as lymphoblast. Aims: 1. To know the relative incidence of Acute Lymphoblastic leukemia among the patients referred for complete haemogram at the department of pathology, JJMMC, Davangere. 2. To study the clinical manifestations and their correlation with various types of acute Lymphoblastic leukemia. 3. To study the haematological profiles in acute Lymphoblastic leukemia. Settings and design: The study was a hospital based study conducted at haematology unit, Department of Pathology, JJM Medical college, Davangere. Methods and material: The present study was done during the period of June 2006 to May 2008 at haematology unit department of Pathology, JJM Medical college, Davangere. Cases from chigateri general hospital, Bapuji hospital and other private hospitals situated in and around Davangere were included for the study. The case selection was based on clinical features and supported by laboratory evidence. Bone marrow aspiration was subsequently carried out after obtaining written consent from the patient or the guardian. Statistics: The results were expressed in percentage. Results and conclusion: A total of 1039 patients who were referred to the department of haematology out of which 13 patients were diagnosed as Acute Lymphoblastic Leukemia. The present study is to highlight that light microscopic features of peripheral smear and bone marrow will still remain mainstay in the diagnosis of acute Lymphoblastic leukemias.
