Clove (Eugenia Caryophyllata) Extraction and Synthesis of New Pyrazole Derivatives from Eugenol

1
M. Khouili
M. Khouili
2
S. Hamri
S. Hamri
3
K. Rhazri
K. Rhazri
4
A. Hafid
A. Hafid
5
H. Ouchetto
H. Ouchetto
6
Y.Hajbi
Y.Hajbi
1 Faculty Science and Technology, University Sultan Moulay Slimane

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Clove (Eugenia Caryophyllata) Extraction and Synthesis of New Pyrazole Derivatives from Eugenol Banner
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An efficient method for the preparation of novel 1,3,4-trisubstituted 4,5-dihydro-1H- pyrazoles via 1,3-dipolar cycloaddition has been described. Using this method, various pyrazole were synthesized from eugenol, a major phenolic constituent of clove bud essential oil, as dipolarophilic system and N-aryl-C-ethoxycarbonitrilimine: the (Z)-ethyl 2-bromo-2-(2-(4chlorophenyl)-hydrazono) acetate.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

M. Khouili. 2013. \u201cClove (Eugenia Caryophyllata) Extraction and Synthesis of New Pyrazole Derivatives from Eugenol\u201d. Global Journal of Science Frontier Research - B: Chemistry GJSFR-B Volume 13 (GJSFR Volume 13 Issue B7): .

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Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

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December 25, 2013

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English

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An efficient method for the preparation of novel 1,3,4-trisubstituted 4,5-dihydro-1H- pyrazoles via 1,3-dipolar cycloaddition has been described. Using this method, various pyrazole were synthesized from eugenol, a major phenolic constituent of clove bud essential oil, as dipolarophilic system and N-aryl-C-ethoxycarbonitrilimine: the (Z)-ethyl 2-bromo-2-(2-(4chlorophenyl)-hydrazono) acetate.

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Clove (Eugenia Caryophyllata) Extraction and Synthesis of New Pyrazole Derivatives from Eugenol

S. Hamri
S. Hamri
K. Rhazri
K. Rhazri
A. Hafid
A. Hafid
H. Ouchetto
H. Ouchetto
Y.Hajbi
Y.Hajbi
M. Khouili
M. Khouili Faculty Science and Technology, University Sultan Moulay Slimane

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