Comparative Antimicrobial Activity of Ethanol and Hexane Leaf Extracts of Ficus Exasperata on Five Microbial Isolates

Comparative Antimicrobial Activity of Ethanol and Hexane Leaf Extracts of Ficus Exasperata on Five Microbial Isolates

Godwill Azeh Engwa

Contact

Richard N. Tagbo

Contact

Chinedu Chukwuekezie

Contact

Marcellus Unaegbu

Contact

Marian N. Unachukwu

Contact

Comparative Antimicrobial Activity of Ethanol and Hexane Leaf Extracts of Ficus Exasperata on Five Microbial Isolates

Article Fingerprint

ReserarchID

PDDTM66Q65

Comparative Antimicrobial Activity of Ethanol and Hexane Leaf Extracts of Ficus Exasperata on Five Microbial Isolates Banner

AI TAKEAWAY

Connecting with the Eternal Ground

Abstract

This study evaluated the antimicrobial activity of Ficus exasperata and compared the efficacy of ethanol and hexane extracts on five microbial isolates. To ascertain the set objective, after extraction with ethanol and hexane, the disk and well diffusion agar methods were employed to investigate the antimicrobial activity of the extracts and its minimum inhibitory and bactericidal concentrations. A phytochemical screening was done for the confirmation of the result and the data was statistically analysed.

References

41 Cites in Article

Reference Format

Robert Pinner,L Teutsch,L Simonsen,J Klug,M Graber,R Berkelman (1996). Trends in Infectious Diseases Mortality in the United States.
C Murry,A Lopez (1997). Mortality by cause for eight regions of the world: global burden of disease study.
S Shira (2008). An introduction to infectious diseases.
E Kenrad (2014). Epidermiology of Infectious disease: General principles, Jones and Bartlett publishers.
A El-Mahmood,J Doughari,N Ladan (2008). Antimicrobial screening of stem bark extracts of Vitellaria paradoxa against some enteric pathogenic micro-organisms.
C Dawson (2013). P155: Technologies to measure hand hygiene: examining the incorporation of the World Health Organisation (WHO) 5 moments.
K Sanjoy (2003). Yogeshwer S. Herbal Medicine: Current Status and the Future.
J Rivera,A Loya,R Ceballos (2013). Use of Herbal Medicines and Implications for Conventional Drug Therapy Medical Sciences.
N Mshana,D Abbiw,I Addae-Mensah,E Adjanohoun,Mra Ahyi (2014). Traditional Medicine and Pharmacopoeia: Contribution to the Revision ethanobotanical and floristic studies in Ghana. 1st edition, Organization of African Unity/Scientific.
P Akah,O Orisakwe,K Gamaniel,A Shittu (1998). Evaluation of Nigerian traditional medicines: II. Effects of some folk remedies on peptic ulcer.
(1969). Catalogue of the library of the Royal Botanic Gardens, Kew.
T Abbiw (1990). Case study 1: Cement plant.
H Burkill (1997). The useful plants of tropical West Africa. 43rd Ed.
E Woode,R Poku,Wkm Abotsi (2011). Anticonvulsant effects of a leaf extract of Ficus exasperata Vahl (Moraceae) in Mice.
Wmk Abotsi,E Woode,A Ainooson,A Amo-Baromah,E Boakye-Gyasi (2010). Antiathritic and antioxidant effects of the leaf extract of Ficus exasperata P. Beauv (Moraceae).
B Ayinde,E Mogbai,Amaechina,Fc (2007). Pharmacognosy and hypotensive evaluation of Ficus exasperata Vahl (Moraceae) leaf.
Castel-Branco, M.M.,Alves, G.L.,Figueiredo, I.V.,Falcao, A.C.,Caramona, M.M. (2009). The maximal electroshock seizure (MES) model in the preclinical assessment of potential new antiepileptic drugs.
I Ijeh,A Ukweni (2007). Acute effect of administration of ethanol extracts of Ficus exasperata Vahl (Moraceae) on kidney function in Albino rats.
E Woode,R Poku,G Ainooson,E Boakye-Gyasi,Wkm Abotsi,T Mensah,A Amo-Baromah (2009). An evaluation of the antiinflammatory, anti-pyretic, and antinociceptive effects of Ficus exasperata Vahl leaf extract.
O Odunbaku,O Ilusanya,Akasoro,Ks (2008). Antibacterial activity of ethanolic leaf extract of Ficus exasperata on Escherichia coli and Staphylococcus albus.
A Buniyamin,Kiq Eric,C Fabian (2007). Pharmacognosy and Hypotensive evaluation of Ficus exasperata Vahl (moraceae) leave.
M Sonibare,A Isiaka,M Taruka,N Williams,M Soladoye,O Emmanuel (2006). Constituents of Ficus exasperata leaves.
E Williamson (2001). Synergy and other interactions in phytomedicines.
M Berenbaum (1989). What is synergy?.
A Engwa,P Nnamdi,J Nnadi,T Offor,B Eze (2013). Comparative Qualitative Analysis of the Phytochemical Load of Water, Methanol, Ethyl Acetate and Hexane Extracts of Six Selected Medicinal Plants.
B Lapornik,M Prosek,A Wondra (2005). Comparison of extracts prepared from plant by products using different solvents and extraction time.
E Adebayo,Ishiola (2009). Evaluations of the methanolic extract of Ficus exasperata stem, bark, leaf and root for phytochemical analysis and antimicrobial activities.
B Adeniyi,H Odelola,B Oso (1996). Antimicrobial potential of Diospyros mesiliforus (Ebenaceae).
J Robbers,M Speedie,V Tyler (1996). Pharmacognosy and Pharmacobiotechnology.
A Sofawa (1993). Medicinal And traditional medicine in Africa.
G Trease,W Evans (1989). Trease and Evans' Pharmacognosy.
Jb ; Harbone,Mbakwem (1973). Effects of Ficus Exasperata Vahl on Common Dermatophytes and Causative Agent of Pityriasis Versicolor in Rivers State, Nigeria.
N Ncube,A Afolayan,A Okoh (2008). Assessment techniques of antimicrobial properties of natural compounds of plant origin: current methods and future trends.
K Das,Rks Tiwari,D Shrivastava (2010). Techniques for evaluation of medicinal plant products as antimicrobial agent: Current methods and future trends.
F Chinedu,U Uyai,A Emezie,A Utoh-Nedosa (2012). Anti-diarrhoeal, antispasmodic and phytochemical properties of ethanol extract of the leaves of Ficus exasperate.
I Lawal,T Borokini,A Oyeleye,O Williams,J Olayemi (2012). Evaluation of Extract of Ficus Exasperata Vahl Root Bark for Antimicrobial Activities Against Some Strains of Clinical Isolates of Bacteria and Fungi.
Osamuyimen Igbinosa,Isoken Igbinosa,Vincent Chigor,Olohirere Uzunuigbe,Sunday Oyedemi,Emmanuel Odjadjare,Anthony Okoh,Etinosa Igbinosa (2009). Polyphenolic Contents and Antioxidant Potential of Stem Bark Extracts from Jatropha curcas (Linn).
Mandana Bimakr,Russly Rahman,Farah Taip,Ali Ganjloo,Liza Salleh,Jinap Selamat,Azizah Hamid,I Zaidul (2010). Comparison of different extraction methods for the extraction of major bioactive flavonoid compounds from spearmint (Mentha spicata L.) leaves.
J Eloff (1998). Which extractant should be used for the screening and isolation of antimicrobial components from plants.
S Handa,Sps Khanuja,G Longo,D Rakesh (2008). Extraction Technologies for Medicinal and Aromatic Plants.
G Wang (2010). vivo anthelmintic activity of five alkaloids from Macleaya microcarpa (Maxim) Fedde.

Download References

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Godwill Azeh Engwa. 2015. \u201cComparative Antimicrobial Activity of Ethanol and Hexane Leaf Extracts of Ficus Exasperata on Five Microbial Isolates\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 15 (GJMR Volume 15 Issue B1): .

More Citation Formats

Select Citation Style:

Download Citation

Download Article

GJMR Volume 15 Issue B1
Pg. 21- 28

Explore Journals Explore Volume Read This Issue

Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

Not Found

Classification

GJMR-B Classification: NLMC Code: QV 752

Submission ReceivedApril 14, 2015
Peer Review Double Blind
Handling Editor
Accepted May 1, 2015
Published May 15, 2015

Version of record

v1.2

Issue date

May 19, 2015

Language

Experiance in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

View in VR

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

View in 3D

Article Matrices

Total Score: 105

Country: Nigeria

Subject: Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine

Authors: Godwill Azeh Engwa, Richard N. Tagbo, Chinedu Chukwuekezie, Marcellus Unaegbu, Marian N. Unachukwu (PhD/Dr. count: 0)

View Count (all-time): 165

Total Views (Real + Logic): 4381

Total Downloads (simulated): 2157

Publish Date: 2015 05, Tue

Monthly Totals (Real + Logic):

Month 1: 35 views
Month 2: 50 views
Month 3: 64 views
Month 4: 54 views
Month 5: 35 views
Month 6: 44 views
Month 7: 32 views
Month 8: 44 views
Month 9: 48 views
Month 10: 27 views
Month 11: 25 views
Month 12: 38 views
Month 13: 28 views
Month 14: 48 views
Month 15: 23 views
Month 16: 40 views
Month 17: 37 views
Month 18: 35 views
Month 19: 21 views
Month 20: 15 views
Month 21: 39 views
Month 22: 28 views
Month 23: 36 views
Month 24: 22 views
Month 25: 19 views
Month 26: 24 views
Month 27: 23 views
Month 28: 43 views
Month 29: 39 views
Month 30: 36 views
Month 31: 36 views
Month 32: 41 views
Month 33: 22 views
Month 34: 29 views
Month 35: 18 views
Month 36: 43 views
Month 37: 16 views
Month 38: 41 views
Month 39: 29 views
Month 40: 37 views
Month 41: 31 views
Month 42: 15 views
Month 43: 31 views
Month 44: 26 views
Month 45: 32 views
Month 46: 33 views
Month 47: 24 views
Month 48: 19 views
Month 49: 36 views
Month 50: 32 views
Month 51: 24 views
Month 52: 25 views
Month 53: 27 views
Month 54: 39 views
Month 55: 30 views
Month 56: 44 views
Month 57: 30 views
Month 58: 22 views
Month 59: 36 views
Month 60: 47 views
Month 61: 14 views
Month 62: 25 views
Month 63: 36 views
Month 64: 36 views
Month 65: 32 views
Month 66: 34 views
Month 67: 38 views
Month 68: 14 views
Month 69: 37 views
Month 70: 32 views
Month 71: 36 views
Month 72: 33 views
Month 73: 26 views
Month 74: 25 views
Month 75: 26 views
Month 76: 39 views
Month 77: 22 views
Month 78: 23 views
Month 79: 41 views
Month 80: 21 views
Month 81: 34 views
Month 82: 22 views
Month 83: 30 views
Month 84: 22 views
Month 85: 28 views
Month 86: 31 views
Month 87: 44 views
Month 88: 36 views
Month 89: 40 views
Month 90: 32 views
Month 91: 43 views
Month 92: 28 views
Month 93: 39 views
Month 94: 22 views
Month 95: 32 views
Month 96: 38 views
Month 97: 22 views
Month 98: 28 views
Month 99: 25 views
Month 100: 25 views
Month 101: 35 views
Month 102: 18 views
Month 103: 41 views
Month 104: 19 views
Month 105: 42 views
Month 106: 27 views
Month 107: 38 views
Month 108: 35 views
Month 109: 38 views
Month 110: 31 views
Month 111: 32 views
Month 112: 32 views
Month 113: 35 views
Month 114: 44 views
Month 115: 25 views
Month 116: 22 views
Month 117: 37 views
Month 118: 22 views
Month 119: 34 views
Month 120: 22 views
Month 121: 48 views
Month 122: 25 views
Month 123: 39 views
Month 124: 41 views
Month 125: 32 views
Month 126: 39 views
Month 127: 52 views
Month 128: 18 views
Month 129: 24 views
Month 130: 42 views
Month 131: 48 views
Month 132: 42 views

Total Views: 4381

Total Downloads: 2157

2026 Trends

Published Article

Our website is actively being updated, and changes may occur frequently. Please clear your browser cache if needed. For feedback or error reporting, please email [email protected]