Comparative Efficacy, Safety and Cost Analysis of Amisulpride vs Olanzapine for Treatment of Schizophrenia

1
Harsh Bansal
Harsh Bansal
2
Nishita Gandhi
Nishita Gandhi
3
Vidhu Arora
Vidhu Arora
4
Shahpoor Shirzada
Shahpoor Shirzada
5
Sinchana S Kadur
Sinchana S Kadur
6
Donald D Savariah
Donald D Savariah
7
Haritha harikrishnan
Haritha harikrishnan
8
Falaq Fida
Falaq Fida
1 pacific medical college and hospital

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Schizophrenia is a psychiatric disorder associated with a range of psychological, behavioural and cognitive problems especially. Nowadays, atypical antipsychotics are the mainstay for the treatment of shizophrenia. Among them amisulpride and olanzapine are the most commonly used atypical antipsychotics. The objective of this study is to compare the efficacy, safety and cost analysis of amisulpride vs olanzapine for the treatment of schizophrenia. It is a double blind, randomised control clinical trial conducted over a period of 12 weeks. A total of 90 patients were included which were randomly divided into two groups. Group A consisting of 39 patients who received amisulpride tablet( 400mg/day) and group B consisting of 38 patients received olanzapine tablet (10mg/day). The brief psychiatric rating scale (BPRS) was taken as main evaluation parameter for the effectiveness of treatment.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

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No ethics committee approval was required for this article type.

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Not applicable for this article.

Harsh Bansal. 2026. \u201cComparative Efficacy, Safety and Cost Analysis of Amisulpride vs Olanzapine for Treatment of Schizophrenia\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 23 (GJMR Volume 23 Issue B3): .

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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January 2, 2024

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Schizophrenia is a psychiatric disorder associated with a range of psychological, behavioural and cognitive problems especially. Nowadays, atypical antipsychotics are the mainstay for the treatment of shizophrenia. Among them amisulpride and olanzapine are the most commonly used atypical antipsychotics. The objective of this study is to compare the efficacy, safety and cost analysis of amisulpride vs olanzapine for the treatment of schizophrenia. It is a double blind, randomised control clinical trial conducted over a period of 12 weeks. A total of 90 patients were included which were randomly divided into two groups. Group A consisting of 39 patients who received amisulpride tablet( 400mg/day) and group B consisting of 38 patients received olanzapine tablet (10mg/day). The brief psychiatric rating scale (BPRS) was taken as main evaluation parameter for the effectiveness of treatment.

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Comparative Efficacy, Safety and Cost Analysis of Amisulpride vs Olanzapine for Treatment of Schizophrenia

Harsh Bansal
Harsh Bansal pacific medical college and hospital
Nishita Gandhi
Nishita Gandhi
Vidhu Arora
Vidhu Arora
Shahpoor Shirzada
Shahpoor Shirzada
Sinchana S Kadur
Sinchana S Kadur
Donald D Savariah
Donald D Savariah
Haritha harikrishnan
Haritha harikrishnan
Falaq Fida
Falaq Fida

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