Comparison between Vitamin D deficiency and 17-beta-Estradiol Decline in Postmenopausal Osteoporotic Iraqi Women
Background: In osteoporotic postmenopausal women, both Vit D and 17-β-estradiol decreased. These decrements synchronized with many effects on BMD causing a decline in T-score and reduction in bone Calcium content. Each factor affects the bone structure differently, but in the outcome, they both enhance the morbidity and mortality of bone fracture in postmenopausal women. Objective: Determining serum levels of 17-β-estradiol and Vit D in healthy and osteoporotic Iraqi women, exploring the degree of correlation of these parameters with BMD and make a comparison between them using correlation coefficient values. Patients and Methods: Eighty-two Iraqi women recruited in this study. They categorized into two groups. The first contains 50 healthy postmenopausal women, and the second consists of 32 osteoporotic postmenopausal women. T-score was determined using the dual energy X-ray absorptiometry (DEXA) technique. Vit D and 17-β-estradiol were determined using ELISA methods.
