Considerations Necessary Regarding Prostate Cancer with the Options of Surgical Removal of the Prostate Gland or with Androgen Deprivation (Aka Testosterone Inactivating) Therapy (ADT) as Follow-on or Primary Treatment

Article ID

F9T82

Considerations Necessary Regarding Prostate Cancer with the Options of Surgical Removal of the Prostate Gland or with Androgen Deprivation (Aka Testosterone Inactivating) Therapy (ADT) as Follow-on or Primary Treatment

Charles Maack
Charles Maack
DOI

Abstract

Charles (Chuck) Maack (ECaP) – Prostate Cancer continuing patient since 1992, Advocate, Activist, and Mentor to Men so diagnosed and their Caregivers online Worldwide With surgical removal of a cancerous prostate gland, PSA nadir should drop to near total absence well into the ultrasensitive testing level below 0.5ng/ml. If this is not achieved, it is likely all cancer cell activity has not been removed, and further treatment is necessary. A variety of tests should be performed for baseline markers among which should be free Testosterone to determine level as well as any bone issues; deoxypyridinoline (DpD) urine test to determine bone resorption; prolactin level since if high could inhibit ADT therapy as well as cause several other issues (See: https://tinyurl.com/7w5omeo); lipid or fatty acid profile since both de novo and dietary lipids seem to be important contributors to prostate cancer growth and development; inflammation markers since inflammation may drive resistance to androgen deprivation therapy (ADT); and any other markers to aid in determining the best strategy for treatment.

Considerations Necessary Regarding Prostate Cancer with the Options of Surgical Removal of the Prostate Gland or with Androgen Deprivation (Aka Testosterone Inactivating) Therapy (ADT) as Follow-on or Primary Treatment

Charles (Chuck) Maack (ECaP) – Prostate Cancer continuing patient since 1992, Advocate, Activist, and Mentor to Men so diagnosed and their Caregivers online Worldwide With surgical removal of a cancerous prostate gland, PSA nadir should drop to near total absence well into the ultrasensitive testing level below 0.5ng/ml. If this is not achieved, it is likely all cancer cell activity has not been removed, and further treatment is necessary. A variety of tests should be performed for baseline markers among which should be free Testosterone to determine level as well as any bone issues; deoxypyridinoline (DpD) urine test to determine bone resorption; prolactin level since if high could inhibit ADT therapy as well as cause several other issues (See: https://tinyurl.com/7w5omeo); lipid or fatty acid profile since both de novo and dietary lipids seem to be important contributors to prostate cancer growth and development; inflammation markers since inflammation may drive resistance to androgen deprivation therapy (ADT); and any other markers to aid in determining the best strategy for treatment.

Charles Maack
Charles Maack

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Charles Maack. 2019. “. Global Journal of Medical Research – F: Diseases GJMR-F Volume 19 (GJMR Volume 19 Issue F4): .

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-F Classification: NLMC Code: WJ 752
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Considerations Necessary Regarding Prostate Cancer with the Options of Surgical Removal of the Prostate Gland or with Androgen Deprivation (Aka Testosterone Inactivating) Therapy (ADT) as Follow-on or Primary Treatment

Charles Maack
Charles Maack

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