Cytotoxic Effects, Phytochemical and GC/MS Analyses of Bosciasenegalensis.L Leave Extracts

§ Omdurman Islamic University

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Cytotoxic Effects, Phytochemical and GC/MS Analyses of Bosciasenegalensis.L Leave Extracts

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Abstract

Boscia senegalensis leaves which were traditionally used to relief intestinal pain in Sudan were tested for secondary metabolites and cytotoxic effects. The result indicated a moderate presence of alkaloids, highly presence of tannins, weakly presence of flavonoids and steroids and negative results for saponin, phenolic compound and triterpens. Methanolic extract was tested for cytotoxicity against brine shrimp larvae. Remarkable cytotoxicity was revealed with high value equal to 1.975 µg/ml. Also the extract was subjected to separation by column chromatography technique, four fractions were obtained. The fractions tested for cytotoxicity against brine shrimp larvae again. F 1 , F 2 , F 3 and F 4 represented high values equal to 66.13. 11.07, 1.74 and 99.41 µg/ml respectively. F 3 with high cytotoxicity was chosen for gas chromatography / mass spectrometry analysis. Thirty-five compounds were not recorded in any previous work in available literature were obtained. The high cytotoxicity of this fraction due to presence of octadecenoic and n-hexadecenoic acid which are known to have anticancer activity.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Manal A Ibrahim, Adam Kh Musa. 2021. "Cytotoxic Effects, Phytochemical and GC/MS Analyses of Bosciasenegalensis.L Leave Extracts". Global Journal of Science Frontier Research - C: Biological Science GJSFR-C Volume 21 (GJSFR Volume 21 Issue C1).

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Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

Keywords
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GJSFR-C Classification FOR Code: 270499
Version of record

v1.2

Issue date
March 8, 2021

Language
English
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Cytotoxic Effects, Phytochemical and GC/MS Analyses of Bosciasenegalensis.L Leave Extracts

Manal Ibrahim
Manal Ibrahim Omdurman Islamic University
Adam Musa
Adam Musa