Design, Synthesis, Spectral Charecterization of Some New Fully Unsaturated 2-Substituted-4, 6 Dichloro  Symmetric Triazine- Based Chalcone Hybrids

Design, Synthesis, Spectral Charecterization of Some New Fully Unsaturated 2-Substituted-4, 6 Dichloro Symmetric Triazine- Based Chalcone Hybrids

G.V.Pavan Kumar

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D. Srinivasa Rao

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B. Pooja

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G. Harika

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Y. Anil Kumar

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Acharya Nagarjuna University

Design, Synthesis, Spectral Charecterization of Some New Fully Unsaturated 2-Substituted-4, 6 Dichloro Symmetric Triazine- Based Chalcone Hybrids

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Abstract

Triazines and chalcones are interesting class of heterocyclic compounds with a prominent structural core system present in numerous pharmacologically active compounds. It is proved from the literature that the compounds containing 1,3,5-triazine moiety or chalcone bridge often shows significant biological activity profiles. Based on these observations, it was considered worthwhile to synthesize and characterize some new 1,3,5-triazine-chalcone hybrid molecules in the present investigation. As a part of our research program aimed at search for new hybrid pharmacophores as potential cytotoxic agents, we are interested to have α,β-unsaturated ketone linker to the 1,3,5-triazine basic nucleus to give a series of 1,3,5-triazinechalcone hybrid molecules. Therefore, in the present study an attempt has been made to synthesize and characterize various analogs of fully unsaturated 2-substituted-4,6 dichloro-1,3,5 triazine based chalcone hybrids.

References

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

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Not applicable for this article.

How to Cite This Article

G.V.Pavan Kumar. 2016. \u201cDesign, Synthesis, Spectral Charecterization of Some New Fully Unsaturated 2-Substituted-4, 6 Dichloro Symmetric Triazine- Based Chalcone Hybrids\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 16 (GJMR Volume 16 Issue B1).

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GJMR Volume 16 Issue B1

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-B Classification NLMC Code: QV 4

Submission ReceivedDecember 16, 2015
Peer Review Double Blind
Handling Editor
Accepted January 1, 2016
Published January 15, 2016

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v1.2

Issue date

May 31, 2016

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Article Matrices

Total Score: 105

Country: India

Subject: Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine

Authors: G. V. Pavan Kumar, D. Srinivasa Rao, B. Pooja, G. Harika, Y. Anil Kumar (PhD/Dr. count: 0)

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Publish Date: 2016 05, Tue

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Total Views: 3885

Total Downloads: 1831

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