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Design, Synthesis, Spectral Charecterization of Some New Fully Unsaturated 2-Substituted-4, 6 Dichloro Symmetric Triazine- Based Chalcone Hybrids

§ Kc Reddy Institute of Pharmaceutical Sciences

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Design, Synthesis, Spectral Charecterization of Some New Fully Unsaturated 2-Substituted-4, 6 Dichloro  Symmetric Triazine- Based Chalcone Hybrids

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MR96826

Design, Synthesis, Spectral Charecterization of Some New Fully Unsaturated 2-Substituted-4, 6 Dichloro  Symmetric Triazine- Based Chalcone Hybrids Banner

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Abstract

Triazines and chalcones are interesting class of heterocyclic compounds with a prominent structural core system present in numerous pharmacologically active compounds. It is proved from the literature that the compounds containing 1,3,5-triazine moiety or chalcone bridge often shows significant biological activity profiles. Based on these observations, it was considered worthwhile to synthesize and characterize some new 1,3,5-triazine-chalcone hybrid molecules in the present investigation. As a part of our research program aimed at search for new hybrid pharmacophores as potential cytotoxic agents, we are interested to have α,β-unsaturated ketone linker to the 1,3,5-triazine basic nucleus to give a series of 1,3,5-triazinechalcone hybrid molecules. Therefore, in the present study an attempt has been made to synthesize and characterize various analogs of fully unsaturated 2-substituted-4,6 dichloro-1,3,5 triazine based chalcone hybrids.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

G.V.Pavan Kumar, B. Pooja, G. Harika, Y. Anil Kumar. 2016. "Design, Synthesis, Spectral Charecterization of Some New Fully Unsaturated 2-Substituted-4, 6 Dichloro Symmetric Triazine- Based Chalcone Hybrids". Global Journal of Medical Research GJMR-B Volume 16 (GJMR Volume 16 Issue 12 (B1)).

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Journal Specifications

Crossref Journal DOI 10.17406/gjmr

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords
Classification
GJMR-B Classification NLMC Code: QV 4
Version of record
v1.2

Issue date
April 13, 2016

Language
English
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Design, Synthesis, Spectral Charecterization of Some New Fully Unsaturated 2-Substituted-4, 6 Dichloro Symmetric Triazine- Based Chalcone Hybrids

G.V.Pavan Kumar
G.V.Pavan Kumar Kc Reddy Institute of Pharmaceutical Sciences
B. Pooja
B. Pooja <p>Kc Reddy Institute of Pharmaceutical Sciences</p>
G. Harika
G. Harika <p>Kc Reddy Institute of Pharmaceutical Sciences</p>
Y. Kumar
Y. Kumar <p>Kc Reddy Institute of Pharmaceutical Sciences</p>