Diabetic Nephropathy: Causative and Protective factors

Diabetic Nephropathy: Causative and Protective factors

Liang Zhou

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Guanjing Zhang

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Zhiyan Xu

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Khrystyna Pronyuk

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Xingming Chen

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Hairong Wang

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Diabetic Nephropathy: Causative and Protective factors

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Abstract

Diabetic nephropathy (DN) is the major cause of chronic kidney disease (CKD) which normally leads to end stage renal disease (ESRD) or dialysis. Despite vigorous management including treatment of hypertension, glyceamic control and the utilization of inhibitors of renin angiotensin system (RAS), a significant proportion of diabetic patients still develop CKD and progress to ESRD. Advances in understanding of the pathogenesis and pathology of DN have made it clear that DN occurs as a result of imbalance between causative factors and endogenous protective factors. To emphasize this concept, this review will focus on some of the current knowledge concerning both causative and endogenous protective factors of DN.

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How to Cite This Article

Liang Zhou. 2015. \u201cDiabetic Nephropathy: Causative and Protective factors\u201d. Global Journal of Medical Research - F: Diseases GJMR-F Volume 15 (GJMR Volume 15 Issue F2): .

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GJMR Volume 15 Issue F2
Pg. 17- 26

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-F Classification: NLMC Code: WK 550, WK 810

Submission ReceivedApril 7, 2015
Peer Review Double Blind
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Accepted May 1, 2015
Published May 15, 2015

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Total Score: 136

Country: China

Subject: Global Journal of Medical Research - F: Diseases

Authors: Guanjing Zhang, Liang Zhou, Zhiyan Xu, Khrystyna Pronyuk, Xingming Chen, Hairong Wang (PhD/Dr. count: 0)

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