Early Diagnosis and Nutritional Treatment Stabilizes Neuropsychiatric Disorders

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Ian James Martins
Ian James Martins

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Abstract

The reliable diagnostic identification of neuropsychiatric disorders such as schizophrenia, bipolar disease, and depression has been associated with some biological markers (genomics, proteomics, metabolomics) but to date, these markers do not have the sensitivity/specificity of a diagnostic test. Biomarker tests that are relevant to global chronic disease are now applicable to neuropsychiatric diseases to prevent autoimmune disease, endoplasmic reticulum stress associated mitophagy with relevance to neuron apoptosis. Metabolic abnormalities has been linked to neuropsychiatric disorder with the careful nutritional assessment of patients reported in many published studies. Early interventions with genomic medicine now assist in the prevention of autoimmune disease associated with global chronic disease and neuropsychiatric disorders.

References

72 Cites in Article
  1. K Taber,R Hurley,S Yudofsky (2010). Diagnosis and treatment of neuropsychiatric disorders.
  2. I Martins (2015). Diabetes and Organ Dysfunction in the Developing and Developed World.
  3. I Martins (2018). Branched-Chain Amino Acids: The Metabolic Link Between Type 2 Diabetes Mellitus and Cardiovascular Disease?.
  4. Sunil Kota,Lalit Meher,Sruti Jammula,S Krishna,Siva Kota,Kirtikumar Modi (2012). Neuropsychiatric screening in type 2 diabetes mellitus.
  5. Yatan Balhara (2011). Diabetes and psychiatric disorders.
  6. Levitt Katz,L Swami,S Abraham,M Murphy,K Jawad,A (2005). Neuropsychiatric disorders at the presentation of type 2 diabetes mellitus in children.
  7. I Martins (2018). Genomic Medicine and Endocrine Autoimmunity as Key to Mitochondrial Disease.
  8. D Kerr,C Krishnan,M Pucak,J Carmen (2005). The immune system and neuropsychiatric diseases.
  9. Aarane Ratnaseelan,Irene Tsilioni,Theoharis Theoharides (2018). Effects of Mycotoxins on Neuropsychiatric Symptoms and Immune Processes.
  10. G Morris,M Berk (2015). The many roads to mitochondrial dysfunction in neuroimmune and neuropsychiatric disorders.
  11. Franziska Radtke,Gareth Chapman,Jeremy Hall,Yasir Syed (2017). Modulating Neuroinflammation to Treat Neuropsychiatric Disorders.
  12. David Horrobin,A Glen,Krishna Vaddadi (1994). The membrane hypothesis of schizophrenia.
  13. E Schaeffer,W Gattaz,G Eckert (2012). Alterations of Brain Membranes in Schizophrenia: Impact of Phospholipase A2.
  14. I Martins (2018). Increased Risk for Obesity and Diabetes with Neurodegeneration in Developing Countries.
  15. Shivangi Patel,Dilip Sharma,Kiran Kalia,Vinod Tiwari (2017). Crosstalk between endoplasmic reticulum stress and oxidative stress in schizophrenia: The dawn of new therapeutic approaches.
  16. Neil Sprenkle,Savannah Sims,Cristina Sánchez,Gordon Meares (2017). Endoplasmic reticulum stress and inflammation in the central nervous system.
  17. D Lindholm,L Korhonen,O Eriksson,S Kõks (2017). Recent Insights into the Role of Unfolded Protein Response in ER Stress in Health and Disease.
  18. Douglas Wallace (2017). A Mitochondrial Etiology of Neuropsychiatric Disorders.
  19. Samantha Marin,Russell Saneto (2016). Neuropsychiatric Features in Primary Mitochondrial Disease.
  20. Liming Pei,Douglas Wallace (2018). Mitochondrial Etiology of Neuropsychiatric Disorders.
  21. D Marazziti,S Baroni,M Picchetti,P Landi,S Silvestri,E Vatteroni,M Catena Dell'osso (2011). Mitochondrial Alterations and Neuropsychiatric Disorders.
  22. Erin Heinzen,Benjamin Neale,Stephen Traynelis,Andrew Allen,David Goldstein (2015). The Genetics of Neuropsychiatric Diseases: Looking In and Beyond the Exome.
  23. A Corvin,G Donohoe,A Hargreaves,L Gallagher,M Gill (2012). The Cognitive Genetics of Neuropsychiatric Disorders.
  24. D Dick,B Riley,K Kendler (2010). Nature and nurture in neuropsychiatric genetics: where do we stand?.
  25. Ian Martins (2016). Anti-Aging Genes Improve Appetite Regulation and Reverse Cell Senescence and Apoptosis in Global Populations.
  26. I Martins (2017). Single Gene Inactivation with Implications to Diabetes and Multiple Organ Dysfunction Syndrome.
  27. Carolyn Ptak,Arturas Petronis (2010). Epigenetic approaches to psychiatric disorders.
  28. Melissa Mahgoub,Lisa Monteggia (2013). Epigenetics and Psychiatry.
  29. T Kishi,Y Fukuo,T Kitajima,T Okochi,Y Yamanouchi,Y Kinoshita,K Kawashima,T Inada,H Kunugi,T Kato,T Yoshikawa,H Ujike,N Ozaki,N Iwata (2011). SIRT1 gene, schizophrenia and bipolar disorder in the Japanese population: an association study.
  30. G Lu,J Li,H Zhang,X Zhao,L-J Yan (2018). Role and Possible Mechanisms of Sirt1 in Depression.
  31. H-D Kim,J Hesterman,T Call,S Magazu,E Keeley,K Armenta,H Kronman,R Neve,E Nestler,D Ferguson (2016). SIRT1 Mediates Depression-Like Behaviors in the Nucleus Accumbens.
  32. Snehajyoti Chatterjee,Ted Abel (2016). To Stay Happy, Keep Your SIRT1 Active.
  33. Juhyun Song,Jongpil Kim (2016). Role of Sirtuins in Linking Metabolic Syndrome with Depression.
  34. L Lo Iacono,F Visco-Comandini,A Valzania,M Viscomi,M Coviello,A Giampà,L Roscini,E Bisicchia,A Siracusano,A Troisi,S Puglisi-Allegra,V Carola (2015). Adversity in childhood and depression: linked through SIRT1.
  35. Naoko Abe-Higuchi,Shusaku Uchida,Hirotaka Yamagata,Fumihiro Higuchi,Teruyuki Hobara,Kumiko Hara,Ayumi Kobayashi,Yoshifumi Watanabe (2016). Hippocampal Sirtuin 1 Signaling Mediates Depression-like Behavior.
  36. Xiaosong Bu,De Wu,Xiaomei Lu,Li Yang,Xiaoyan Xu,Juan Wang,Jiulai Tang (2017). Role of SIRT1/PGC-1α in mitochondrial oxidative stress in autistic spectrum disorder.
  37. A Herskovits,Leonard Guarente (2014). SIRT1 in Neurodevelopment and Brain Senescence.
  38. Stanley Chan,Xuechan Zhao,Abdulsalam Elfowiris,Cherubina Ratnam,Terence Herbert (2017). The role of de novo protein synthesis and SIRT1 in ER stress-induced Atf4 and Chop mRNA expression in mammalian cells.
  39. Tae Jung,Kyoung-Tae Lee,Myung Lee,Kang-Hyeon Ka (2012). SIRT1 attenuates palmitate-induced endoplasmic reticulum stress and insulin resistance in HepG2 cells via induction of oxygen-regulated protein 150.
  40. Y Li,S Xu,A Giles,K Nakamura,J Lee (2011). Hepatic over expression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver.
  41. Tomoaki Koga,Mary Suico,Shogo Shimasaki,Eriko Watanabe,Yukari Kai,Kosuke Koyama,Kohei Omachi,Saori Morino-Koga,Takashi Sato,Tsuyoshi Shuto,Kazutoshi Mori,Shinjiro Hino,Mitsuyoshi Nakao,Hirofumi Kai (2015). Endoplasmic Reticulum (ER) Stress Induces Sirtuin 1 (SIRT1) Expression via the PI3K-Akt-GSK3β Signaling Pathway and Promotes Hepatocellular Injury.
  42. A Prola,Da Pires,J Silva,A Guilbert,L Lecru,J Piquereau (2017). SIRT1 protects the heart from ER stress-induced cell death through eIF2α deacetylation.
  43. Ian Martins (2018). Heat Shock Gene Inactivation and Protein Aggregation with Links to Chronic Diseases.
  44. I Martins (2017). The Future of Genomic Medicine Involves the Maintenance of Sirtuin 1 in Global Populations.
  45. J Martinsi (2016). Bacterial Lipopolysaccharides Change Membrane Fluidity with Relevance to Phospholipid and Amyloid Beta Dynamics in Alzheimer’s Disease.
  46. Ian Martins (2015). LPS Regulates Apolipoprotein E and A<i>β</i> Interactionswith Effects on Acute Phase Proteins and Amyloidosis.
  47. I Martins (2018). Appetite Regulation and the Peripheral Sink Amyloid beta Clearance Pathway in Diabetes and Alzheimer's Disease. Top 10 Commentaries in Alzheimer's Disease.
  48. C Müller,M Reichel,C Mühle,C Rhein,E Gulbins (2015). Brain membrane lipids in major depression and anxiety disorders.
  49. P Kidd (2004). Bipolar disorder and cell membrane dysfunction. Progress toward integrative management.
  50. Ian Martins (2015). Overnutrition Determines LPS Regulation of Mycotoxin Induced Neurotoxicity in Neurodegenerative Diseases.
  51. Jill Karatinos,Richard Rosse,Stephen Deutsch (1995). The Nitric Oxide Pathway.
  52. O Akyol,S Zoroglu,F Armutcu,S Sahin,A Gurel (2004). Nitric oxide as a physiopathological factor in neuropsychiatric disorders.
  53. Martins Ij (2017). Antimicrobial activity inactivation and toxic immune reactions induce Epilepsy in humans.
  54. I Martins (2015). Nutritional diets accelerate amyloid beta metabolism and prevent the induction of chronic diseases and Alzheimer's disease.
  55. Philip Harvey,Robert Heaton,William Carpenter,Michael Green,James Gold,Michael Schoenbaum (2012). Diagnosis of schizophrenia: Consistency across information sources and stability of the condition.
  56. Assen Jablensky (2010). The diagnostic concept of schizophrenia: its history, evolution, and future prospects.
  57. Larry Goldman,Nancy Nielsen,Hunter Champion (1999). Awareness, diagnosis, and treatment of depression.
  58. A Rush (1990). Associated psychopathology in winter depression.
  59. K Smith,P Renshaw,J Bilello (2013). The diagnosis of depression: current and emerging methods.
  60. Larry Culpepper (2014). The Diagnosis and Treatment of Bipolar Disorder.
  61. I Martins (2018). Sirtuin 1, a Diagnostic Protein Marker and its Relevance to Chronic Disease and Therapeutic Drug Interventions.
  62. Ian Martins (2016). Magnesium Therapy Prevents Senescence with the Reversal of Diabetes and Alzheimer’s Disease.
  63. I Martins (2017). Nutrition Therapy Regulates Caffeine Metabolism with Relevance to NAFLD and Induction of Type 3 Diabetes.
  64. C Tessier,K Sweers,A Frajerman,H Bergaoui,F Ferreri,C Delva,N Lapidus,A Lamaziere,J Roiser,M De Hert,P Nuss (2016). Membrane lipidomics in schizophrenia patients: a correlational study with clinical and cognitive manifestations.
  65. I Martins (2017). The Future of Biomarkers Tests and Genomic Medicine in Global Organ Disease.
  66. I Martins (2017). Biomarker Tests and Ageing Science.
  67. Martin Strassnig,Jaspreet Singh Brar,Rohan Ganguli (2005). Dietary fatty acid and antioxidant intake in community-dwelling patients suffering from schizophrenia.
  68. Salvatore Dipasquale,Carmine Pariante,Paola Dazzan,Eugenio Aguglia,Philip Mcguire,Valeria Mondelli (2013). The dietary pattern of patients with schizophrenia: A systematic review.
  69. Bryan Kraft,Eric Westman (2009). Schizophrenia, gluten, and low-carbohydrate, ketogenic diets: a case report and review of the literature.
  70. Sathyanarayana Rao,T Asha,M Ramesh,B,Jagannatha Rao,K (2008). Understanding nutrition, depression and mental illnesses.
  71. Ian Martins (2017). Functional Foods and Active molecules with relevance to Health and Chronic disease.
  72. I Martins (2015). Unhealthy Nutrigenomic Diets Accelerate NAFLD and Adiposity in Global communities.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Ian James Martins. 2019. \u201cEarly Diagnosis and Nutritional Treatment Stabilizes Neuropsychiatric Disorders\u201d. Global Journal of Medical Research - A: Neurology & Nervous System GJMR-A Volume 18 (GJMR Volume 18 Issue A1): .

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords
Classification
GJMR-A Classification: NLMC Code: WM 102
Version of record

v1.2

Issue date

January 8, 2019

Language
en
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The reliable diagnostic identification of neuropsychiatric disorders such as schizophrenia, bipolar disease, and depression has been associated with some biological markers (genomics, proteomics, metabolomics) but to date, these markers do not have the sensitivity/specificity of a diagnostic test. Biomarker tests that are relevant to global chronic disease are now applicable to neuropsychiatric diseases to prevent autoimmune disease, endoplasmic reticulum stress associated mitophagy with relevance to neuron apoptosis. Metabolic abnormalities has been linked to neuropsychiatric disorder with the careful nutritional assessment of patients reported in many published studies. Early interventions with genomic medicine now assist in the prevention of autoimmune disease associated with global chronic disease and neuropsychiatric disorders.

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Early Diagnosis and Nutritional Treatment Stabilizes Neuropsychiatric Disorders

Ian James Martins
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