Early Virological Response of the First Line Combination Therapy (Pegylated Interferon I-2a and Ribavirin) in Iraqi Chronic Hepatitis C Patients and Their Psychological Adverse Effects

1
Dr. Vian Ahmed Wasta Ismael
Dr. Vian Ahmed Wasta Ismael
2
Prof. Dr. Kassim Al-Shamma & Dr. Hiwa Abubakir Hussein
Prof. Dr. Kassim Al-Shamma & Dr. Hiwa Abubakir Hussein
1 Hawler Medical University

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GJMR Volume 12 Issue 11

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Early Virological Response of the First Line Combination Therapy (Pegylated Interferon I-2a and Ribavirin) in Iraqi Chronic Hepatitis C Patients and Their Psychological Adverse Effects Banner
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This study was designed to assess short-term therapeutic effectiveness and psychological adverse effects of combination of pegylated interferon α-2a and ribavirin in Iraqi chronic hepatitis C patients. For this purpose fifty newly diagnosed chronic hepatitis C patients divided into three groups A, B and C, treated with equal doses of pegylated interferon α-2a (180 μg/week) and different doses of ribavirin (1200, 1000 and 800 mg/day respectively) and followed up for 12 weeks of starting treatment (prospective groups). Twenty healthy subjects were selected to be a normal group for the purpose of comparison. The results at week 12 (the time of achieving EVR) showed 100% complete EVR (cEVR) in group A, 4.4% cEVR and 5.6% null response in group B, 88.9% cEVR and 11.1% partial response in group C.

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No external funding was declared for this work.

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The authors declare no conflict of interest.

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No ethics committee approval was required for this article type.

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Not applicable for this article.

Dr. Vian Ahmed Wasta Ismael. 1970. \u201cEarly Virological Response of the First Line Combination Therapy (Pegylated Interferon I-2a and Ribavirin) in Iraqi Chronic Hepatitis C Patients and Their Psychological Adverse Effects\u201d. Unknown Journal GJMR Volume 12 (GJMR Volume 12 Issue 11): .

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January 8, 2013

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This study was designed to assess short-term therapeutic effectiveness and psychological adverse effects of combination of pegylated interferon α-2a and ribavirin in Iraqi chronic hepatitis C patients. For this purpose fifty newly diagnosed chronic hepatitis C patients divided into three groups A, B and C, treated with equal doses of pegylated interferon α-2a (180 μg/week) and different doses of ribavirin (1200, 1000 and 800 mg/day respectively) and followed up for 12 weeks of starting treatment (prospective groups). Twenty healthy subjects were selected to be a normal group for the purpose of comparison. The results at week 12 (the time of achieving EVR) showed 100% complete EVR (cEVR) in group A, 4.4% cEVR and 5.6% null response in group B, 88.9% cEVR and 11.1% partial response in group C.

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Early Virological Response of the First Line Combination Therapy (Pegylated Interferon I-2a and Ribavirin) in Iraqi Chronic Hepatitis C Patients and Their Psychological Adverse Effects

Dr. Vian Ahmed Wasta Ismael
Dr. Vian Ahmed Wasta Ismael Hawler Medical University
Prof. Dr. Kassim Al-Shamma & Dr. Hiwa Abubakir Hussein
Prof. Dr. Kassim Al-Shamma & Dr. Hiwa Abubakir Hussein

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