Echocardiographic Profile in Newly Diagnosed Patients with Obstructive Sleep Apnoea (OSA) and Normal LV Ejection Fraction: A Prospective Study

Anender Kaur Dhariwal; Prakash Sanzgiri; Charan Reddy KV; Vidya Suratkal; Suresh Vijan

Echocardiographic Profile in Newly Diagnosed Patients with Obstructive Sleep Apnoea (OSA) and Normal LV Ejection Fraction: A Prospective Study

Anender Kaur Dhariwal *

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Prakash Sanzgiri

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Charan Reddy KV

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Vidya Suratkal

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Suresh Vijan

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MRU3214

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Abstract

OSA is considered as an independent risk factor for cardiovascular morbidity and mortality. Hypertension, atrial fibrillation, heart failure with reduced ejection fraction, stroke and metabolic syndrome are also known to be associated with OSA. Each of these conditions are associated with 2D-ECHO abnormalities and often present with increased hospitalization rates or morbidity. However, echocardiographic parameters in newly detected OSA, without any other associated illness, is poorly defined. The aim of this study is to evaluate systolic and diastolic dysfunction using 2D speckle tracking in patients with newly diagnosed OSA and normal left ventricle ejection fraction. The association between diastolic dysfunction, Global Longitudinal Strain (GLS), LV hypertrophy, LV mass, estimated pulmonary artery pressures and severity of OSA was also studied. The results indicated that most of the patients with OSA, without any other cardiovascular diseases, exhibited normal left ventricular (LV) ejection fraction (EF), but had clinical signs and symptoms of LV systolic dysfunction.

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11 Cites in Article

Reference Format

Kashif Kalam,Petr Otahal,Thomas Marwick (2014). Prognostic implications of global LV dysfunction: a systematic review and meta-analysis of global longitudinal strain and ejection fraction.
V Kapur,D Auckley,S Chowdhuri,D Kuhlmann,R Mehra,K Ramar,C Harrod (2017). Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: an American Academy of Sleep Medicine clinical practice guideline.
Roberto Lang,Luigi Badano,Victor Mor-Avi,Jonathan Afilalo,Anderson Armstrong,Laura Ernande,Frank Flachskampf,Elyse Foster,Steven Goldstein,Tatiana Kuznetsova,Patrizio Lancellotti,Denisa Muraru,Michael Picard,Ernst Rietzschel,Lawrence Rudski,Kirk Spencer,Wendy Tsang,Jens-Uwe Voigt (2015). Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging.
J Hedner,H Ejnell,K Caidahl (1990). Left ventricular hypertrophy independent of hypertension in patients with obstructive sleep apnea.
Rolf Wachter,Lars Lüthje,Daniela Klemmstein,Claus Lüers,Raoul Stahrenberg,Frank Edelmann,Volker Holzendorf,Gerd Hasenfuß,Stefan Andreas,Burkert Pieske (2013). Impact of obstructive sleep apnoea on diastolic function.
K Cho,J Kwon,S Kim,T Park,H Lee,T Kim (2012). Impact of Obstructive Sleep Apnea on the Global Myocardial Performance beyond Obesity.
Refik Altekin,Atakan Yanikoglu,Mustafa Karakas,Deniz Ozel,Aytul Yildirim,Mehmet Kabukcu (2012). Evaluation of subclinical left ventricular systolic dysfunction in patients with obstructive sleep apnea by automated function imaging method; an observational study.
Nian-Wei Zhou,Xian-Hong Shu,Yi-Li Liu,Hong Shen,Wen-Jing Li,Xue Gong,Hai-Yan Chen,Wei-Peng Zhao,Cui-Zhen Pan,Shan-Qun Li (2016). A Novel Method for Sensitive Determination of Subclinical Left-Ventricular Systolic Dysfunction in Subjects With Obstructive Sleep Apnea.
N Haruki,M Takeuchi,Y Kanazawa,N Tsubota,R Shintome,H Nakai,R Lang,Y Otsuji (2010). Continuous positive airway pressure ameliorates sleep-induced subclinical left ventricular systolic dysfunction: demonstration by two-dimensional speckle-tracking echocardiography.
Cyrus Kholdani,Wassim Fares,Vahid Mohsenin (2015). Pulmonary Hypertension in Obstructive Sleep Apnea: Is it Clinically Significant? a Critical Analysis of the Association and Pathophysiology.
Mehmood Butt,Girish Dwivedi,Alena Shantsila,Omer Khair,Gregory Lip (2012). Left Ventricular Systolic and Diastolic Function in Obstructive Sleep Apnea.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Anender Kaur Dhariwal, Prakash Sanzgiri, Charan Reddy KV, Vidya Suratkal, Suresh Vijan. 2020. "Echocardiographic Profile in Newly Diagnosed Patients with Obstructive Sleep Apnoea (OSA) and Normal LV Ejection Fraction: A Prospective Study". Global Journal of Medical Research - F: Diseases GJMR-F Volume 20 (GJMR Volume 20 Issue F4).

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GJMR Volume 20 Issue F4

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Journal Specifications

Crossref Journal DOI 10.17406/gjmr

Print ISSN 0975-5888

e-ISSN 2249-4618

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Classification

GJMR-F Classification NLMC Code: WL 108

Submission ReceivedDecember 6, 2019
Peer Review Double Blind
Handling Editor
Accepted January 1, 2020
Published January 15, 2020

Version of record

v1.2

Issue date

April 20, 2020

Language

English

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