Efficacy of Intravenous Acetaminophen Compared to Oral Acetaminophen for the Management of Fever in Children

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Dr. Shailendra Kumar
Dr. Shailendra Kumar
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Abhishek Pathak
Abhishek Pathak

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GJMR Volume 19 Issue F4

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Introduction-Human body temperature is controlled by the hypothalamus. Neurons in both the preoptic anterior hypothalamus and the posterior hypothalamus receive two kinds of signals: one from peripheral nerves that transmit information from warmth/cold receptors in the skin and the other from the temperature of the blood bathing the region. These two types of signals are integrated by the thermoregulatory center of the hypothalamus to maintain normal temperature. In a neutral temperature environment, the metabolic rate of humans produces more heat than is necessary to maintain the core body temperature in the range of 36.5-37.5°C (97.7-99.5°F). A normal body temperature is maintained ordinarily, despite environmental variations, because the hypothalamic thermoregulatory center balances the excess heat production derived from metabolic activity in muscle and the liver with heat dissipation from the skin and lungs. [1

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No external funding was declared for this work.

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The authors declare no conflict of interest.

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Dr. Shailendra Kumar. 2019. \u201cEfficacy of Intravenous Acetaminophen Compared to Oral Acetaminophen for the Management of Fever in Children\u201d. Global Journal of Medical Research - F: Diseases GJMR-F Volume 19 (GJMR Volume 19 Issue F4): .

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-F Classification: NLMC Code: WB 152
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v1.2

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June 13, 2019

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English

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Introduction-Human body temperature is controlled by the hypothalamus. Neurons in both the preoptic anterior hypothalamus and the posterior hypothalamus receive two kinds of signals: one from peripheral nerves that transmit information from warmth/cold receptors in the skin and the other from the temperature of the blood bathing the region. These two types of signals are integrated by the thermoregulatory center of the hypothalamus to maintain normal temperature. In a neutral temperature environment, the metabolic rate of humans produces more heat than is necessary to maintain the core body temperature in the range of 36.5-37.5°C (97.7-99.5°F). A normal body temperature is maintained ordinarily, despite environmental variations, because the hypothalamic thermoregulatory center balances the excess heat production derived from metabolic activity in muscle and the liver with heat dissipation from the skin and lungs. [1

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Efficacy of Intravenous Acetaminophen Compared to Oral Acetaminophen for the Management of Fever in Children

Dr. Shailendra Kumar
Dr. Shailendra Kumar
Abhishek Pathak
Abhishek Pathak

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