Efﬁcacy of Intravenous Acetaminophen Compared to Oral Acetaminophen for the Management of Fever in Children

Efﬁcacy of Intravenous Acetaminophen Compared to Oral Acetaminophen for the Management of Fever in Children

Dr. Shailendra Kumar

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Abhishek Pathak

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Efﬁcacy of Intravenous Acetaminophen Compared to Oral Acetaminophen for the Management of Fever in Children

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Abstract

Introduction-Human body temperature is controlled by the hypothalamus. Neurons in both the preoptic anterior hypothalamus and the posterior hypothalamus receive two kinds of signals: one from peripheral nerves that transmit information from warmth/cold receptors in the skin and the other from the temperature of the blood bathing the region. These two types of signals are integrated by the thermoregulatory center of the hypothalamus to maintain normal temperature. In a neutral temperature environment, the metabolic rate of humans produces more heat than is necessary to maintain the core body temperature in the range of 36.5-37.5°C (97.7-99.5°F). A normal body temperature is maintained ordinarily, despite environmental variations, because the hypothalamic thermoregulatory center balances the excess heat production derived from metabolic activity in muscle and the liver with heat dissipation from the skin and lungs. [1

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

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No ethics committee approval was required for this article type.

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Not applicable for this article.

How to Cite This Article

Dr. Shailendra Kumar. 2019. \u201cEfﬁcacy of Intravenous Acetaminophen Compared to Oral Acetaminophen for the Management of Fever in Children\u201d. Global Journal of Medical Research - F: Diseases GJMR-F Volume 19 (GJMR Volume 19 Issue F4).

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GJMR Volume 19 Issue F4

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-F Classification NLMC Code: WB 152

Submission ReceivedDecember 15, 2018
Peer Review Double Blind
Handling Editor
Accepted January 5, 2019
Published January 15, 2019

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v1.2

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June 13, 2019

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