Effect of n-Hexane Oil Extract of two Spices on Serum Lipid Profile and Blood Glucose Concentration of Albino Rats

Effect of n-Hexane Oil Extract of two Spices on Serum Lipid Profile and Blood Glucose Concentration of Albino Rats

Ogunka-Nnoka, CU

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Ogunka-Nnoka C. U.

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Igwe F. U.

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Abstract

Consumers are concerned with their health and physical fitness and are seeking for alternative plant products with potential for providing nutrients with enhanced health benefits. Hence, this study investigates the effect of mixture of Ehuru (Monodora myristica) and Njasang (Ricinodendron heudelotii) oil extract on serum lipid profile and blood glucose concentration of albino rats. The spices were processed into fine flour and the oil was extracted with n-hexane as the solvent. A total of twenty five rats weighing 125-160g were separated into five groups of five each to represent control, olive oil and varying concentrations of the spices. After acclimiatization for one week, experimental administration of the extract was carried out daily for 28 days. Blood samples were collected by cardiac puncture into tubes. A portion of the blood was used for fasting blood glucose determination. Serum was separated from the other portion and used for assay of lipid profile using standard kit methods. The results obtained showed percentage fatty acid yield for Ehuru and Njasang as 79.54 and 81.0 (polyunsaturated) and 13.40 and 15.0 (monounsaturated) respectively. Fasting blood glucose assay showed that only rats in group 1 (6.46mmol/L) became significantly (p

References

21 Cites in Article

Reference Format

S Achinewhu,C Ogbonna,A Hart (1995). Chemical composition of indigenous wild herbs, spices, fruits, nuts and leafy vegetables used as food.
P Angerer,W Kothny,S Stork,C Vonshacky (2002). Effect of dietary supplementation with omega -3 -fatty acids on progression of atherosclerosis in carotid arteries.
O Ajayi,A Fajemilehin,C Dada,O Awolusi (2011). Effect of Tetrapleura tetraptera fruit on plasma lipid profile and enzyme activities in some tissues of hyparcholesterolemic rats.
S Besong,C Fosung,Jones,V Fondong,S Gorinstein,M Leontoweiz (2006). Raw and boiled garlic enhances plasma antioxidant activity and improves plasma lipid metabolism in cholesterol fed rat.
H Guthrie,M Picciano (1995). Human Nutrition WCB.
R Harvey,P Champe (1994). Unknown Title.
Alam Khan,Noella Bryden,Marilyn Polansky,Richard Anderson (1990). Insulin potentiating factor and chromium content of selected foods and spices.
A Khan,M Safdar,K Khan,R Anderson (2003). Cinnamon improves glucose and lipids of people in the type 2 diabetes.
N Manay (1987). Spices in foods. Facts and principles.
L Matos,J Nzikou,A Kimbongnila,C Ndangui,N Pambou-Toby,A Abena,T Silou,J Scher,S Desoby (2009). Composition and Nutritional properties of seeds and oil from Terminalia catappa L.
R Murray,D Granner,P Mayes,V Rodwell (2003). Harper's Biochemistry.
Kaare Norum (1992). Dietary Fat and Blood Lipids.
Kalpana Platel,K Srinivasan (1996). Influence of dietary spices or their active principles on digestive enzymes of small intestinal mucosa in rats.
A Raza,A Movahed (2003). Current concepts of cardiovascular disease in diabetes mellitus Int.
V Sardesai (1992). Nutritional role of polyunsaturated fatty acids.
K Sirinivasan,K Sambaiae (1991). The effect on cholesterol 7 -alpha hydroxylase activity on Serum and hepatic cholesterol levels in the rat.
D Jump (2002). The Biochemistry of n-3 polyunsaturated fatty acids.
N Ugochukwu,N Babady,M Cobourre,S Gasset (2003). The effect of Gonoronema latifolium extract on serum lipid profile and oxpative stress in hepatocytes of diabetic rat.
E Ugwuja,A Nwibo,N Ugwu,C Aloke (2010). Effects of Aqueous Extract of Spices Mixture Containing Curry, Garlic and Ginger on Plasma Glucose and Lipids in Alloxan-induced Diabetic Rats.
E Ugwuja,N Ngwu,A Nwibo (2008). Dietary Supplement Containing Mixture of Raw Curry, Garlic, and Ginger.
T Wahua (1999). Applied statistic for.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Ogunka-Nnoka, CU. 2013. \u201cEffect of n-Hexane Oil Extract of two Spices on Serum Lipid Profile and Blood Glucose Concentration of Albino Rats\u201d. Global Journal of Science Frontier Research - C: Biological Science GJSFR-C Volume 13 (GJSFR Volume 13 Issue C6): .

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GJSFR Volume 13 Issue C6
Pg. 11- 16

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Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

Keywords

ehuru glucose njasang rats serum lipid

Submission ReceivedJuly 28, 2013
Peer Review Double Blind
Handling Editor
Accepted August 18, 2013
Published August 29, 2013

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October 2, 2013

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Total Score: 102

Country: Nigeria

Subject: Global Journal of Science Frontier Research - C: Biological Science

Authors: Ogunka-Nnoka C. U., Igwe F. U. (PhD/Dr. count: 0)

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Total Downloads: 2521

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