Effect of n-Hexane Oil Extract of two Spices on Serum Lipid Profile and Blood Glucose Concentration of Albino Rats

§ Rivers State University of Science and Technology Rivers State University of Science and Technology

Send Message

To: Author

Effect of n-Hexane Oil Extract of two Spices on Serum Lipid Profile and Blood Glucose Concentration of Albino Rats

Article Fingerprint

ReserarchID

6O1CR

Effect of n-Hexane Oil Extract of two Spices on Serum Lipid Profile and Blood Glucose Concentration of Albino Rats Banner

Key Research Insights

Synthesized scholarly intelligence & interactive research assistant
  • English
  • Afrikaans
  • Albanian
  • Amharic
  • Arabic
  • Armenian
  • Azerbaijani
  • Basque
  • Belarusian
  • Bengali
  • Bosnian
  • Bulgarian
  • Catalan
  • Cebuano
  • Chichewa
  • Chinese (Simplified)
  • Chinese (Traditional)
  • Corsican
  • Croatian
  • Czech
  • Danish
  • Dutch
  • Esperanto
  • Estonian
  • Filipino
  • Finnish
  • French
  • Frisian
  • Galician
  • Georgian
  • German
  • Greek
  • Gujarati
  • Haitian Creole
  • Hausa
  • Hawaiian
  • Hebrew
  • Hindi
  • Hmong
  • Hungarian
  • Icelandic
  • Igbo
  • Indonesian
  • Irish
  • Italian
  • Japanese
  • Javanese
  • Kannada
  • Kazakh
  • Khmer
  • Korean
  • Kurdish (Kurmanji)
  • Kyrgyz
  • Lao
  • Latin
  • Latvian
  • Lithuanian
  • Luxembourgish
  • Macedonian
  • Malagasy
  • Malay
  • Malayalam
  • Maltese
  • Maori
  • Marathi
  • Mongolian
  • Myanmar (Burmese)
  • Nepali
  • Norwegian
  • Pashto
  • Persian
  • Polish
  • Portuguese
  • Punjabi
  • Romanian
  • Russian
  • Samoan
  • Scots Gaelic
  • Serbian
  • Sesotho
  • Shona
  • Sindhi
  • Sinhala
  • Slovak
  • Slovenian
  • Somali
  • Spanish
  • Sundanese
  • Swahili
  • Swedish
  • Tajik
  • Tamil
  • Telugu
  • Thai
  • Turkish
  • Ukrainian
  • Urdu
  • Uzbek
  • Vietnamese
  • Welsh
  • Xhosa
  • Yiddish
  • Yoruba
  • Zulu
Reading Preferences
Font Size
Line Spacing
Background
This converted HTML version may contain rendering inconsistencies. Please refer to the PDF for the authoritative version, or click here to provide feedback.

Abstract

Consumers are concerned with their health and physical fitness and are seeking for alternative plant products with potential for providing nutrients with enhanced health benefits. Hence, this study investigates the effect of mixture of Ehuru (Monodora myristica) and Njasang (Ricinodendron heudelotii) oil extract on serum lipid profile and blood glucose concentration of albino rats. The spices were processed into fine flour and the oil was extracted with n-hexane as the solvent. A total of twenty five rats weighing 125-160g were separated into five groups of five each to represent control, olive oil and varying concentrations of the spices. After acclimiatization for one week, experimental administration of the extract was carried out daily for 28 days. Blood samples were collected by cardiac puncture into tubes. A portion of the blood was used for fasting blood glucose determination. Serum was separated from the other portion and used for assay of lipid profile using standard kit methods. The results obtained showed percentage fatty acid yield for Ehuru and Njasang as 79.54 and 81.0 (polyunsaturated) and 13.40 and 15.0 (monounsaturated) respectively. Fasting blood glucose assay showed that only rats in group 1 (6.46mmol/L) became significantly (p

References

21 Cites in Article
  1. 1. S Achinewhu,C Ogbonna,A Hart (1995). Chemical composition of indigenous wild herbs, spices, fruits, nuts and leafy vegetables used as food. Plant Foods for Human Nutrition, 48(4), 341-348.
  2. 2. P Angerer,W Kothny,S Stork,C Vonshacky (2002). Effect of dietary supplementation with omega -3 -fatty acids on progression of atherosclerosis in carotid arteries. Cardiovasc Res, 54, 183-186.
  3. 3. O Ajayi,A Fajemilehin,C Dada,O Awolusi (2011). Effect of Tetrapleura tetraptera fruit on plasma lipid profile and enzyme activities in some tissues of hyparcholesterolemic rats. J. Nat. Prod. Plant Resour, 1(4), 47-55.
  4. 4. S Besong,C Fosung,Jones,V Fondong,S Gorinstein,M Leontoweiz (2006). Raw and boiled garlic enhances plasma antioxidant activity and improves plasma lipid metabolism in cholesterol fed rat. Life Sci, 78, 655-663.
  5. 5. H Guthrie,M Picciano (1995). Human Nutrition WCB. Human Nutrition WCB, 136-140.
  6. 6. R Harvey,P Champe (1994). Unknown Title. Biochemistry -Lippnocott's illustrated Review, 3, 179.
  7. 7. Alam Khan,Noella Bryden,Marilyn Polansky,Richard Anderson (1990). Insulin potentiating factor and chromium content of selected foods and spices. Biological Trace Element Research, 24(2-3), 183-188.
  8. 8. A Khan,M Safdar,K Khan,R Anderson (2003). Cinnamon improves glucose and lipids of people in the type 2 diabetes. Diabetes care, 26, 3215-3218.
  9. 9. N Manay (1987). Spices in foods. Facts and principles. Spices in foods. Facts and principles, 300-334.
  10. 10. L Matos,J Nzikou,A Kimbongnila,C Ndangui,N Pambou-Toby,A Abena,T Silou,J Scher,S Desoby (2009). Composition and Nutritional properties of seeds and oil from Terminalia catappa L. Adv. J. food Sci. Tech, 1(1), 72-77.
  11. 11. R Murray,D Granner,P Mayes,V Rodwell (2003). Harper's Biochemistry. Harper's Biochemistry, 268-297.
  12. 12. Kaare Norum (1992). Dietary Fat and Blood Lipids. Nutrition Reviews, 50(4), 30-37.
  13. 13. Kalpana Platel,K Srinivasan (1996). Influence of dietary spices or their active principles on digestive enzymes of small intestinal mucosa in rats. International Journal of Food Sciences and Nutrition, 47(1), 55-59.
  14. 14. A Raza,A Movahed (2003). Current concepts of cardiovascular disease in diabetes mellitus Int. J. Cardiol, 89, 123-134.
  15. 15. V Sardesai (1992). Nutritional role of polyunsaturated fatty acids. The Journal of Nutritional Biochemistry, 3(4), 154-166.
  16. 16. K Sirinivasan,K Sambaiae (1991). The effect on cholesterol 7 -alpha hydroxylase activity on Serum and hepatic cholesterol levels in the rat. Int. J. of Vits. and Nutr. Research, 61(4), 364-369.
  17. 17. D Jump (2002). The Biochemistry of n-3 polyunsaturated fatty acids. J. Biochem, 2, 8755-8758.
  18. 18. N Ugochukwu,N Babady,M Cobourre,S Gasset (2003). The effect of Gonoronema latifolium extract on serum lipid profile and oxpative stress in hepatocytes of diabetic rat. Journal of Biol. Sc, 28, 1-5.
  19. 19. E Ugwuja,A Nwibo,N Ugwu,C Aloke (2010). Effects of Aqueous Extract of Spices Mixture Containing Curry, Garlic and Ginger on Plasma Glucose and Lipids in Alloxan-induced Diabetic Rats. Pakistan Journal of Nutrition, 9(12), 1131-1135.
  20. 20. E Ugwuja,N Ngwu,A Nwibo (2008). Dietary Supplement Containing Mixture of Raw Curry, Garlic, and Ginger. The Internet Journal of Nutrition and Wellness, 5(2)
  21. 21. T Wahua (1999). Applied statistic for. Applied statistic for

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Ogunka-Nnoka C. U.. 2013. "Effect of n-Hexane Oil Extract of two Spices on Serum Lipid Profile and Blood Glucose Concentration of Albino Rats". Global Journal of Science Frontier Research - C: Biological Science GJSFR-C Volume 13 (GJSFR Volume 13 Issue C6).

Download Citation

Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

Keywords
Classification
GJSFR-C Classification FOR Code: 270599
Version of record

v1.2

Issue date
October 2, 2013

Language
English
Order Article Reprint
Experiance in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

Article Matrices
Total Views: 2.1K
Total Downloads: 190
All Trends

Request Access

Please fill out the form below to request access to this research paper. Your request will be reviewed by the editorial or author team.
X

This is the heading

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.

High-quality academic research articles on global topics and journals.

Effect of n-Hexane Oil Extract of two Spices on Serum Lipid Profile and Blood Glucose Concentration of Albino Rats

Ogunka-Nnoka U.
Ogunka-Nnoka U. Rivers State University of Science and Technology