Effect of Omega-3 as Adjuvant Therapy to Methotrexate on Lipid Profile in Iraqi Patients with Active Rheumatoid Arthritis

Effect of Omega-3 as Adjuvant Therapy to Methotrexate on Lipid Profile in Iraqi Patients with Active Rheumatoid Arthritis

Shaimaa Saleh Khider

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Ibrahim Adham Majeed

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Muzahim M. Taha

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University of Baghdad

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Abstract

Rheumatoid arthritis (RA) is a common inflammatory disease associated with many extra-articular features. The aim of the current study is to assess the influence of omega-3 fatty acids (EPA,DHA) on serum lipids in patients with active RA. Fifty patients with active RA using MTX were participated in this study. Patients were allocated to take either omega-3 (1000 mg) capsule three times daily or capsules prefilled with glucose as placebo and were evaluatedat zero time (baseline) and after 12 weeks for lipid profile parameters. The RA disease activity was measured using DAS28-ESR and CDAI. After 12 weeks of starting adjuvant treatment with either omega-3 or placebo, it’s found that only TG decreased significantly by omega-3 (p

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

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No ethics committee approval was required for this article type.

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Not applicable for this article.

How to Cite This Article

Shaimaa Saleh Khider. 2013. \u201cEffect of Omega-3 as Adjuvant Therapy to Methotrexate on Lipid Profile in Iraqi Patients with Active Rheumatoid Arthritis\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 13 (GJMR Volume 13 Issue B5): .

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GJMR Volume 13 Issue B5
Pg. 19- 23

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

lipid profile omega-3 rheumatoid arthritis

Submission ReceivedDecember 15, 2012
Peer Review Double Blind
Handling Editor
Accepted December 31, 2012
Published January 15, 2013

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October 24, 2013

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Article Matrices

Total Score: 103

Country: Iraq

Subject: Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine

Authors: Shaimaa Saleh Khider, Ibrahim Adham Majeed, Muzahim M. Taha (PhD/Dr. count: 0)

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Total Views: 4666

Total Downloads: 2553

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