Effect of Oral Administration of Chloramphenicol on Hematological Profile of Male Charles Foster Rats

Effect of Oral Administration of Chloramphenicol on Hematological Profile of Male Charles Foster Rats

P. Shukla

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R. K. Singh

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α Central Drug Research Institute

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Abstract

For a given organism, relevant information about the internal environment can be easily accessed by its hematological profile. Chloramphenicol being a potent broad spectrum antibiotic is used readily in eyed drop formulations and is also in food industry. In the present study, varying doses (750, 1500 and 2250 mg/kg B.Wt) of Chloramphenicol (CAP) was administered orally as single daily dosage for 24 days to Male Charles Foster rats, to assess the hematological changes associated with oral exposure to the drug. The results showed a significant (p

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No external funding was declared for this work.

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The authors declare no conflict of interest.

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How to Cite This Article

P. Shukla. 2013. \u201cEffect of Oral Administration of Chloramphenicol on Hematological Profile of Male Charles Foster Rats\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 13 (GJMR Volume 13 Issue B4): .

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GJMR Volume 13 Issue B4
Pg. 17- 21

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

blood cells CAP CF rats hematotoxicity

Submission ReceivedDecember 8, 2012
Peer Review Double Blind
Handling Editor
Accepted January 2, 2013
Published January 15, 2013

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July 10, 2013

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Total Score: 102

Country: India

Subject: Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine

Authors: P. Shukla, R. K. Singh (PhD/Dr. count: 0)

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