Endocrine Disruptors in Endometriosis

1
Wellerson Rodrigo Scarano
Wellerson Rodrigo Scarano
2
Mariana Antunes Ribeiro
Mariana Antunes Ribeiro
1 Sao Paulo State University

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Endometriosis is an estrogen-dependent disease, which involves the growth of endometrial tissue outside the uterine cavity, commonly in the pelvic region. The etiology of the disease is unclear, but multiple factors may contribute to its prognosis. Toxicological studies indicate that many chemicals are able to interfere with endocrine homeostasis, called endocrine disrupting chemicals (EDC) like Bisphenol A, Phtalate, Polychlorinated Biphenyls and Dioxins. As well documented, endometriosis is an estrogen-dependent disease; therefore, environmental toxicants that either mimic estrogen or enhance estrogenic exposure in the endometrium are thought to increase the risk of endometriosis. The purpose of this mini-review is to provide an overview of epidemiological studies, which have evaluated the relationship between endometriosis and exposure to endocrine disruptors.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

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Not applicable for this article.

Wellerson Rodrigo Scarano. 2016. \u201cEndocrine Disruptors in Endometriosis\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 16 (GJMR Volume 16 Issue B3): .

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-B Classification: NLMC Code: WP 390
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v1.2

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October 13, 2016

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English

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Endometriosis is an estrogen-dependent disease, which involves the growth of endometrial tissue outside the uterine cavity, commonly in the pelvic region. The etiology of the disease is unclear, but multiple factors may contribute to its prognosis. Toxicological studies indicate that many chemicals are able to interfere with endocrine homeostasis, called endocrine disrupting chemicals (EDC) like Bisphenol A, Phtalate, Polychlorinated Biphenyls and Dioxins. As well documented, endometriosis is an estrogen-dependent disease; therefore, environmental toxicants that either mimic estrogen or enhance estrogenic exposure in the endometrium are thought to increase the risk of endometriosis. The purpose of this mini-review is to provide an overview of epidemiological studies, which have evaluated the relationship between endometriosis and exposure to endocrine disruptors.

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Endocrine Disruptors in Endometriosis

Mariana Antunes Ribeiro
Mariana Antunes Ribeiro
Wellerson Rodrigo Scarano
Wellerson Rodrigo Scarano Sao Paulo State University

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