Epilepsy: The Next Generation Drugs (A Review)

Epilepsy: The Next Generation Drugs (A Review)

Amit Kumar Shrivastava

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Amit K. Shrivastava

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Manish Dhar Dwivedi

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Gulzar Alam

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Epilepsy: The Next Generation Drugs (A Review)

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Abstract

Seizures are common and are treated in all branches of medicine. Approximately 10% of the population will have one or more seizures during their lifetime. Seizures are symptoms that occur in acute illness, ie, provoked seizures, or in epilepsy, ie, unprovoked seizures. Antiepileptic drugs (AEDs) are pharmacologic agents used to reduce the frequency of epileptic seizures. “Antiepileptic” drug is a misnomer, because these drugs are effective as symptomatic treatment of seizures, i.e., the symptoms of epilepsy, not as treatment of epilepsy itself. Recent discoveries in molecular biology and genetics have elucidated a genetic basis for some epilepsy syndromes, which will lead to new treatments. This review include new AEDs viz; Ganaxolone, Eslicarbazepine acetate, Fluorofel-bamate, Huperzine A, Carisbamate (RWJ-333369), Brivaracetam (ucb 34714), 2-Deoxy-D-glucose, Retigabine, T2000 , T2007, Valrocemide, Tonabersat (SB-220453), YKP3089, Propyl isopropyl acetamide, JZP-4, ICA-105665, NAX-5055, Perampanel and Valpromide.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

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How to Cite This Article

Amit Kumar Shrivastava. 2014. \u201cEpilepsy: The Next Generation Drugs (A Review)\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 14 (GJMR Volume 14 Issue B4): .

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GJMR Volume 14 Issue B4
Pg. 19- 27

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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Submission ReceivedDecember 11, 2013
Peer Review Double Blind
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Accepted December 31, 2013
Published January 15, 2014

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September 4, 2014

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Total Score: 103

Country: India

Subject: Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine

Authors: Amit K. Shrivastava, Manish Dhar Dwivedi, Gulzar Alam (PhD/Dr. count: 0)

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