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Family of Six, their Health and the Death of a 16 Month Old Male from Pulmonary Hemorrhage: Identification of Mycotoxins and Mold in the Home and Lungs, Liver and Brain of Deceased Infant

Dennis H Hooper
Dennis H Hooper *
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Jeff Taber
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Family of Six, their Health and the Death of a 16 Month Old Male from Pulmonary Hemorrhage: Identification of Mycotoxins and Mold in the Home and Lungs, Liver and Brain of Deceased Infant

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Family of Six, their Health and the Death of a 16 Month Old Male from Pulmonary Hemorrhage: Identification of Mycotoxins and Mold in the Home and Lungs, Liver and Brain of Deceased Infant Banner

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Abstract

The health of a family of six residing in a water- damaged home is presented. The family consisted of the parents (age 29) two boys (ages 8 and 12) and new born fraternal twins (male and female. The parents and two boys developed RADS/asthma and had multiple symptoms including nose bleeds.The fraternal twins experienced respiratory illness that required hospital treatments. The infant girl survived while her brother was found face down, blue in color, lifeless with oral and nasal blood discharge. Pathology demonstrated ares of peribronchial inflammation, intra-alveolar, and numerous hemosiderin laden macrophage (hemosiderosis). Environmental evaluation of the home revealed Stachybotrys, Aspergillus/Penicillium, Cladosporium and Chaetomium in various rooms of the home. Mycotoxins detected in the home included Sterigmatocystin, 5 methoxy-sterigmatocystin Roquefortine C, Satratoxin G and H, Roridin E and L-2, isosatratoxin Fas well as other Stachybotrys secondary metabolites. Aspergillus versicolor was identified by PCR-DNA analysis in the lungs and brain of the deceased child. Aflatoxin was detected in his lungs, while monocyclic trichothecenes were identified in the lungs, liver and brain. The literature is briefly reviewed on the subject of fungi and their secondary metabolites present in water-damaged homes and buildings. w

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

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How to Cite This Article

Jack Dwayne Thrasher, Jeff Taber. 2014. "Family of Six, their Health and the Death of a 16 Month Old Male from Pulmonary Hemorrhage: Identification of Mycotoxins and Mold in the Home and Lungs, Liver and Brain of Deceased Infant". Global Journal of Medical Research - K: Interdisciplinary GJMR-K Volume 14 (GJMR Volume 14 Issue 51 (K5)).

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-K Classification NLMC Code: WH 312
  • Submission ReceivedDecember 11, 2013
  • Peer Review Double Blind
    Handling Editor
  • Accepted January 3, 2014
  • Published October 29, 2014
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Issue date
October 29, 2014

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Family of Six, their Health and the Death of a 16 Month Old Male from Pulmonary Hemorrhage: Identification of Mycotoxins and Mold in the Home and Lungs, Liver and Brain of Deceased Infant

Jack Thrasher
Jack Thrasher
Dennis Hooper
Dennis Hooper
Jeff Taber
Jeff Taber
  • Submission ReceivedDecember 11, 2013
  • Peer Review Double Blind
    Handling Editor
  • Accepted January 3, 2014
  • Published October 29, 2014