First Reporting on the Chemistry and Biological Activity of a Novel Boswellia Chemotype: The Methoxy Alkane Frankincense

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Prabodh Satyal
Prabodh Satyal
2
Robert S Pappas
Robert S Pappas
1 Essential Oil University LLC

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GJSFR Volume 16 Issue B2

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Two oleogum resin essential oils (from two different seasons: fall and summer), of Boswellia spp. (collected from Somalia), were obtained by hydrodistillation and analyzed by GC-MS. Out of 147 peaks, components were identified among the two essential oils accounting for 100%, and 99.7% of the oils, respectively. The two essential oils were dominated by the 1-methoxy alkane [octyl methyl ether (5.5-11.7%), and decyl methyl ether (30.6-54.9%)], α-pinene (0.3-11.5%), sabinene (2.1-7.2%), and αbourbonene(1.7-5.7%). This is the first report of a methoxy alkane chemotyped frankincense essential oils as well as the first reporting of the natural occurance of decyl methyl ether (methyoxy decane) and octyl methyl ether (methyoxy octane). Monoterpenes chiral distributions were also measured and it was found that both of the oils have same enantiomeric ratio. Large chemical variation was attributed to seasonal variation. The essential oil harvested on fall season had also exhibited notable antimicrobial activities [Aspergillus niger (MIC = 39 µg/mL), Candida albicans (MIC = 78 µg/mL), Bacillus cerreus (MIC = 78 µg/mL), Staphylococus aureus (MIC = 78 µg/mL), and Escherichia coli (MIC = 78 µg/mL)], the essential oil also showed pronounced cytotoxic activities (100% kill on MCF-7 cells at 100 μg/mL).

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No external funding was declared for this work.

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The authors declare no conflict of interest.

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No ethics committee approval was required for this article type.

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Not applicable for this article.

Prabodh Satyal. 2016. \u201cFirst Reporting on the Chemistry and Biological Activity of a Novel Boswellia Chemotype: The Methoxy Alkane Frankincense\u201d. Global Journal of Science Frontier Research - B: Chemistry GJSFR-B Volume 16 (GJSFR Volume 16 Issue B2): .

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Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

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GJSFR-B Classification: FOR Code: 250499
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v1.2

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April 14, 2016

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English

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Two oleogum resin essential oils (from two different seasons: fall and summer), of Boswellia spp. (collected from Somalia), were obtained by hydrodistillation and analyzed by GC-MS. Out of 147 peaks, components were identified among the two essential oils accounting for 100%, and 99.7% of the oils, respectively. The two essential oils were dominated by the 1-methoxy alkane [octyl methyl ether (5.5-11.7%), and decyl methyl ether (30.6-54.9%)], α-pinene (0.3-11.5%), sabinene (2.1-7.2%), and αbourbonene(1.7-5.7%). This is the first report of a methoxy alkane chemotyped frankincense essential oils as well as the first reporting of the natural occurance of decyl methyl ether (methyoxy decane) and octyl methyl ether (methyoxy octane). Monoterpenes chiral distributions were also measured and it was found that both of the oils have same enantiomeric ratio. Large chemical variation was attributed to seasonal variation. The essential oil harvested on fall season had also exhibited notable antimicrobial activities [Aspergillus niger (MIC = 39 µg/mL), Candida albicans (MIC = 78 µg/mL), Bacillus cerreus (MIC = 78 µg/mL), Staphylococus aureus (MIC = 78 µg/mL), and Escherichia coli (MIC = 78 µg/mL)], the essential oil also showed pronounced cytotoxic activities (100% kill on MCF-7 cells at 100 μg/mL).

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First Reporting on the Chemistry and Biological Activity of a Novel Boswellia Chemotype: The Methoxy Alkane Frankincense

Prabodh Satyal
Prabodh Satyal Essential Oil University LLC
Robert S Pappas
Robert S Pappas

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