First Reporting on the Chemistry and Biological Activity of a Novel Boswellia Chemotype: The Methoxy Alkane Frankincense

Prabodh Satyal

First Reporting on the Chemistry and Biological Activity of a Novel Boswellia Chemotype: The Methoxy Alkane Frankincense

Prabodh Satyal * §

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First Reporting on the Chemistry and Biological Activity of a Novel Boswellia Chemotype: The Methoxy Alkane Frankincense

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Abstract

Two oleogum resin essential oils (from two different seasons: fall and summer), of Boswellia spp. (collected from Somalia), were obtained by hydrodistillation and analyzed by GC-MS. Out of 147 peaks, components were identified among the two essential oils accounting for 100%, and 99.7% of the oils, respectively. The two essential oils were dominated by the 1-methoxy alkane [octyl methyl ether (5.5-11.7%), and decyl methyl ether (30.6-54.9%)], α-pinene (0.3-11.5%), sabinene (2.1-7.2%), and αbourbonene(1.7-5.7%). This is the first report of a methoxy alkane chemotyped frankincense essential oils as well as the first reporting of the natural occurance of decyl methyl ether (methyoxy decane) and octyl methyl ether (methyoxy octane). Monoterpenes chiral distributions were also measured and it was found that both of the oils have same enantiomeric ratio. Large chemical variation was attributed to seasonal variation. The essential oil harvested on fall season had also exhibited notable antimicrobial activities [Aspergillus niger (MIC = 39 µg/mL), Candida albicans (MIC = 78 µg/mL), Bacillus cerreus (MIC = 78 µg/mL), Staphylococus aureus (MIC = 78 µg/mL), and Escherichia coli (MIC = 78 µg/mL)], the essential oil also showed pronounced cytotoxic activities (100% kill on MCF-7 cells at 100 μg/mL).

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15 Cites in Article

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Prabodh Satyal. 2016. "First Reporting on the Chemistry and Biological Activity of a Novel Boswellia Chemotype: The Methoxy Alkane Frankincense". Global Journal of Science Frontier Research - B: Chemistry GJSFR-B Volume 16 (GJSFR Volume 16 Issue 8 (B2)).

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GJSFR Volume 16 Issue 8 (B2)

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Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

Keywords

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Classification

GJSFR-B Classification FOR Code: 250499

Submission ReceivedFebruary 28, 2016
Peer Review Double Blind
Handling Editor
Accepted March 21, 2016
Published March 18, 2016

Version of record

v1.2

Issue date

March 18, 2016

Language

English

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Article Matrices

Total Score: 132

Country: United States

Subject: Global Journal of Science Frontier Research - B: Chemistry

Authors: Prabodh Satyal, Robert S Pappas (PhD/Dr. count: 0)

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