Formulation and Control of Biodegradable Injectable In Situ Gelling System of Levonorgestrel

Formulation and Control of Biodegradable Injectable In Situ Gelling System of Levonorgestrel

Seyed Mostafa Khezri

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Dr. pegah dadras

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rasoul Dinarvand

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seyed

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mostafa khezri

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Islamic Azad University, Tehran

Formulation and Control of Biodegradable Injectable In Situ Gelling System of Levonorgestrel

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Abstract

The aim of this study was to develop a new polymeric gel that used as a contraceptive system.Polymeric gel has been studied extensively for drug delivery systems. In this article, thermalsensitive poly (DL-lactic acid)-poly (ethylene glycol) -poly (DL-lactic acid) (PLA-PEG-PLA) hydrogel was used as an implantable contraceptive system.Aqueous solution of this copolymer fromed a free flowing so at room temperature and became a gel at body temperature. In this study, the biodegradable copolymer with molecular structure of PLA-PEG-PLA was synthesized and was investigated the sol-gel transition, hydrolytic degradation and In-vitro drug delivery from the system. In the current studyLevonorgestrel was selected as a model contraceptive drug.

References

12 Cites in Article

Reference Format

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Seyed Mostafa Khezri. 2011. \u201cFormulation and Control of Biodegradable Injectable In Situ Gelling System of Levonorgestrel\u201d. Global Journal of Research in Engineering - J: General Engineering GJRE-J Volume 11 (GJRE Volume 11 Issue J7): .

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GJRE Volume 11 Issue J7
Pg. 15- 20

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Journal Specifications

Crossref Journal DOI 10.17406/gjre

Print ISSN 0975-5861

e-ISSN 2249-4596

Keywords

biodegradable in situ injectable sol-gel transition thermal-sensitive

Submission ReceivedMay 16, 2011
Peer Review Double Blind
Handling Editor
Accepted June 11, 2011
Published June 22, 2011

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v1.2

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December 10, 2011

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Article Matrices

Total Score: 89

Country: Iran

Subject: Global Journal of Research in Engineering - J: General Engineering

Authors: Dr. pegah dadras,rasoul Dinarvand,seyed,mostafa khezri, (PhD/Dr. count: 1)

View Count (all-time): 207

Total Views (Real + Logic): 5586

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Publish Date: 2011 12, Sat

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Total Views: 5586

Total Downloads: 2751

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