Neural Networks and Rules-based Systems used to Find Rational and Scientific Correlations between being Here and Now with Afterlife Conditions
February 17, 2026
Neural Networks and Rules-based Systems used to Find Rational and
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PDDTM4JVS5
Crossref Journal DOI 10.17406/gjmra
Print ISSN 0975-5888
e-ISSN 2249-4618
The methods for personal identification and authentication are no exception.
Neural Networks and Rules-based Systems used to Find Rational and
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The present study was aimed towards the design and formulation of medicated nail lacquer of tolnaftate to control onychomycosis condition and improve the patient compliance. The present work investigated the amount of tolnaftate released from different formulations containing different concentration of ethyl cellulose and different proportions of thioglycolic acid and dimethyl sulfoxides for treatment of onychomycosis. Then these lacquers were compared for drying time, nonvolatile content, drug content, drug diffusion and antimicrobial studies. The stability test showed that the formulation were stable at 37° ± 2°C for 1 month. The results obtained from in-vitro diffusion studies showed that formulation F3 have completed drug release of 94.48% over 24 hrs. The F3 formulation had salicylic acid as keratolytic agent and 0.5ml of 1% w/v of thioglycolic acid as penetration enhancer. From diffusion studies, it was concluded that thioglycolic acid containing formulation (F2 and F3) have better penetration enhancement as compared to DMSO containing formulation. The best formulation was evaluated for antifungal sensitivity test against the Candida albicans. From the above study, it can be concluded that medicated nail lacquers proved to be a better tool.
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