Formulation of an Antidiabetic Herbal Capsule from Isolated Compounds of Ethanolic Extract of Dregea Volubilis and Leptadenia Reticulata

Venkatesan Natarajan; Anton Smith. A; Vishwanath. B.A; Suchitra. D

Formulation of an Antidiabetic Herbal Capsule from Isolated Compounds of Ethanolic Extract of Dregea Volubilis and Leptadenia Reticulata

Venkatesan Natarajan * § Professor and Head, Department of Pharmacology, Aditya Bangalore Institute of Pharmacy Education and Research, Bangalore, India - 560064

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Anton Smith. A

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Vishwanath. B.A

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Suchitra. D

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§ Rajiv Gandhi University of Health Sciences

Formulation of an Antidiabetic Herbal Capsule from Isolated Compounds of Ethanolic Extract of Dregea Volubilis and Leptadenia Reticulata

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Abstract

The present investigation was aimed to formulate capsule formulations containing isolated compounds from Dregea volubilis and Leptadenia reticulata. In order to obtain anti diabetic formulations with more effective oral hypoglycemic activity, less side effects, increased patient compliance thereby providing multifaceted benefits. DVLR (DV and LR isolated fraction was mixed in 1:1 ratio) capsules were formulated and the study was carried out for its antidiabetic effect of STZ and HFD induced diabetic rats. Preformulation of capsules were observed as angle of repose and bulk density. Finished capsule formulations were evaluated for weight variation, pH, moisture content, disintegration time, in vitro-drug release percentage and in vivo anti diabetic studies. In our study showed empty capsule shell pH was observed as 3.62 and moisture content of capsule was found as

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15 Cites in Article

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

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Not applicable for this article.

How to Cite This Article

Venkatesan Natarajan, Anton A, Vishwanath. B.A, Suchitra. D. 2021. "Formulation of an Antidiabetic Herbal Capsule from Isolated Compounds of Ethanolic Extract of Dregea Volubilis and Leptadenia Reticulata". Global Journal of Medical Research, Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 21 (GJMR Volume 21 Issue B2).

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GJMR Volume 21 Issue B2

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Journal Specifications

Crossref Journal DOI 10.17406/gjmr

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

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Classification

GJMR-B Classification NLMC Code: WB 330

Submission ReceivedJune 15, 2021
Peer Review Double Blind
Handling Editor
Accepted July 1, 2021
Published July 15, 2021

Version of record

v1.2

Issue date

May 30, 2021

Language

English

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