GC-MS Evaluation of the Phytoconstituents of the Ethanolic and N-Hexane Extracts of the Whole Plant of Cleome Rutidosperma

GC-MS Evaluation of the Phytoconstituents of the Ethanolic and N-Hexane Extracts of the Whole Plant of Cleome Rutidosperma

Article Fingerprint

ReserarchID

M3022

GC-MS Evaluation of the Phytoconstituents of the Ethanolic and N-Hexane Extracts of the Whole Plant of Cleome Rutidosperma Banner

Key Research Insights

Synthesized scholarly intelligence & interactive research assistant
  • English
  • Afrikaans
  • Albanian
  • Amharic
  • Arabic
  • Armenian
  • Azerbaijani
  • Basque
  • Belarusian
  • Bengali
  • Bosnian
  • Bulgarian
  • Catalan
  • Cebuano
  • Chichewa
  • Chinese (Simplified)
  • Chinese (Traditional)
  • Corsican
  • Croatian
  • Czech
  • Danish
  • Dutch
  • Esperanto
  • Estonian
  • Filipino
  • Finnish
  • French
  • Frisian
  • Galician
  • Georgian
  • German
  • Greek
  • Gujarati
  • Haitian Creole
  • Hausa
  • Hawaiian
  • Hebrew
  • Hindi
  • Hmong
  • Hungarian
  • Icelandic
  • Igbo
  • Indonesian
  • Irish
  • Italian
  • Japanese
  • Javanese
  • Kannada
  • Kazakh
  • Khmer
  • Korean
  • Kurdish (Kurmanji)
  • Kyrgyz
  • Lao
  • Latin
  • Latvian
  • Lithuanian
  • Luxembourgish
  • Macedonian
  • Malagasy
  • Malay
  • Malayalam
  • Maltese
  • Maori
  • Marathi
  • Mongolian
  • Myanmar (Burmese)
  • Nepali
  • Norwegian
  • Pashto
  • Persian
  • Polish
  • Portuguese
  • Punjabi
  • Romanian
  • Russian
  • Samoan
  • Scots Gaelic
  • Serbian
  • Sesotho
  • Shona
  • Sindhi
  • Sinhala
  • Slovak
  • Slovenian
  • Somali
  • Spanish
  • Sundanese
  • Swahili
  • Swedish
  • Tajik
  • Tamil
  • Telugu
  • Thai
  • Turkish
  • Ukrainian
  • Urdu
  • Uzbek
  • Vietnamese
  • Welsh
  • Xhosa
  • Yiddish
  • Yoruba
  • Zulu
Reading Preferences
Font Size
Line Spacing
Background
This converted HTML version may contain rendering inconsistencies. Please refer to the PDF for the authoritative version, or click here to provide feedback.

Abstract

Plants are the source of a great variety of phytochemicals, the valuable properties of which have been utilized by human being for centuries ever since the dawn of human civilization. Man has employed therapeutic plants as the greatest bio-resource of remedies for folk and contemporary treatments. Most plant species used as folklore medicine are claimed to retain the capacity to cure or mitigate some health disorders. Cleome rutidosperma has been reported for treatments as anti-inflammatory, antimicrobial, etc. agents. The present investigation was aimed to explore the phytoconstituents of the ethanolic and n-hexane extracts of the entire plant of Cleome rutidosperma employing the GC-MS technique. The extracts were analyzed with Thermo-Finnigan Trace GC Ultra (Waltham, MA, USA) equipped with a splitless injector, coupled to an ion trap mass spectrometer (MS) (Polaris Q) coupled to a Xcalibur data software processor.

References

51 Cites in Article
  1. 1. Pedro Acevedo-Rodr�guez,Mark Strong (2012). Catalogue of Seed Plants of the West Indies. Smithsonian Contributions to Botany, 98, 1-1192.
  2. 2. Kavitha Achar,Kallappa Hosamani,Harisha Seetharamareddy (2010). In-vivo analgesic and anti-inflammatory activities of newly synthesized benzimidazole derivatives. European Journal of Medicinal Chemistry, 45(5), 2048-2054.
  3. 3. M; Adnan,M Nazim Uddin Chy,A Mostafa Kamal,Md Azad,Arkajyoti Paul,Shaikh Uddin,James Barlow,Mohammad Faruque,Cheol Park,Dong Cho (2019). Investigation of the Biological Activities and Characterization of Bioactive Constituents of Ophiorrhiza rugosa var. prostrata (D.Don) & Mondal Leaves through In Vivo, In Vitro, and In Silico Approaches. Molecules, 24(7), 1367.
  4. 4. P Akah,A Nwambie (1993). Nigerian plants with anti-convulsant property. Fitoterapia, 64, 42-44.
  5. 5. A Alamgir (2017). Therapeutic Use of Medicinal Plants and Their Extracts: Volume 1. Therapeutic Use of Medicinal Plants and Their Extracts: Volume 1, 1
  6. 6. P; Alarcon,C; Manosalva,J; Quiroga,I; Belmar,K; Alvarez,G; Díaz,A Taubert,C; Hermosilla,D Carretta,A Burgos,A Hidalgo (2020). Oleic and Linoleic Acids Induce the Release of Neutrophil Extracellular Traps via Pannexin 1-Dependent ATP Release and P2X1 Receptor Activation. Frontiers in Veterinary Sciences, 7, 260.
  7. 7. Ammar Altemimi,Naoufal Lakhssassi,Azam Baharlouei,Dennis Watson,David Lightfoot (2017). Phytochemicals: Extraction, Isolation, and Identification of Bioactive Compounds from Plant Extracts. Plants, 6(4), 42.
  8. 8. R Alves,I Rosa (2005). Why study the use of animal products in traditional medicines?. Journal of Ethnobiology and Ethnomedicine, 1, 1-5.
  9. 9. Vasudevan Aparna,Kalarickal Dileep,Pradeep Mandal,Ponnuraj Karthe,Chittalakkottu Sadasivan,Madathilkovilakathu Haridas (2012). Anti‐Inflammatory Property of <i>n</i>‐Hexadecanoic Acid: Structural Evidence and Kinetic Assessment. Chemical Biology & Drug Design, 80(3), 434-439.
  10. 10. Marcy Balunas,A Kinghorn (2005). Drug discovery from medicinal plants. Life Sciences, 78(5), 431-441.
  11. 11. A Bose,J Gupta,G Dash,T Ghosh,S Si,D Panda (2004). Diuretic and antibacterial activity of aqueous extract of <i> Cleome rutidosperma</i> D.C. Indian Journal of Pharmaceutical Sciences, 69(2), 292.
  12. 12. Anindya Bose,Sumanta Mondal,Jayanta Gupta,Tirtha Ghosh,Gouri Dash,Sudam Si (2006). Analgesic, anti-inflammatory and antipyretic activities of the ethanolic extract and its fractions of Cleome rutidosperma. Fitoterapia, 78(7-8), 515-520.
  13. 13. A; Bose,J Gupta,G Dash,T Ghosh,S Si,D Panda (2007). Diuretic and antibacterial activity of aqueous extract of <i> Cleome rutidosperma</i> D.C. Indian Journal of Pharmaceutical Sciences, 69(2), 292.
  14. 14. Anindya Bose,Sumanta Mondal,Jayanta Gupta,Tirtha Ghosh,Debabrata Debbhuti,Sudam Si (2017). Antioxidant and free radical scavenging activities of Cleome rutidosperma. Oriental Pharmacy and Experimental Medicine, 8(2), 135-145.
  15. 15. Madhusmita Borthakur,Arun Gurung,Atanu Bhattacharjee,S Joshi (2020). Analysis of the Bioactive Metabolites of the Endangered Mexican Lost Fungi <i>Campanophyllum</i> – A Report from India. Mycobiology, 48(1), 58-69.
  16. 16. A Chakoborty,H Roy (2010). Evaluation of anti-arthritic activity of ethanolic extract of Cleome rutidosperma. J Pharm Sci Tech, 2(10), 330-332.
  17. 17. Shi-Lin Chen,Hua Yu,Hong-Mei Luo,Qiong Wu,Chun-Fang Li,André Steinmetz (2016). Conservation and sustainable use of medicinal plants: problems, progress, and prospects. Chinese Medicine, 11(1), 37.
  18. 18. Ian Cole,Praveen Saxena,Susan Murch (2007). Medicinal biotechnology in the genus scutellaria. In Vitro Cellular & Developmental Biology - Plant, 43(4), 318-327.
  19. 19. Cenzo Congiu,Maria Cocco,Valentina Onnis (2008). Design, synthesis, and in vitro antitumor activity of new 1,4-diarylimidazole-2-ones and their 2-thione analogues. Bioorganic & Medicinal Chemistry Letters, 18(3), 989-993.
  20. 20. Daniel Dias,Sylvia Urban,Ute Roessner (2012). A Historical Overview of Natural Products in Drug Discovery. Metabolites, 2(2), 303-336.
  21. 21. S; Feng,T; Belwa,L Li,J; ; Limwachiranon,X Liu,Z Luo (2020). Phytosterols and their derivatives: Potential health-promoting uses against lipid metabolism and associated diseases, mechanism, and safety issues. Comprehensive Reviews in Food Science and Food Safety, 19, 1243-1267.
  22. 22. P; Ghosh,S; Chatterjee,P; Das,A; Banerjee,S Karmakar,S Mahapatra (2019). Natural habitat, phytochemistry and pharmacological properties of a medicinal weed-Cleome rutidosperma DC. (Cleomaceae): a comprehensive review. International Journal of Pharmaceutical Sciences and Research, 10(4), 1605-1612.
  23. 23. M; Govindappa,S; Prathap,V Vinay,R Channabasava (2014). " Antioxidant Activities of Ethyl Acetic Extract of Endophytic Fungi from Caesalpinia sappan L. and Eucheuma sp. International Journal of Pharmaceutical Research, 10(03), 861-869.
  24. 24. Preeti Gupta,Shahul Hameed,Rahul Jain (2004). Ring-substituted imidazoles as a new class of anti-tuberculosis agents. European Journal of Medicinal Chemistry, 39(9), 805-814.
  25. 25. F; Hadizadeh,H; Hosseinzadeh,S Motamed-Shariaty,M V; Seifi,S Kazemi (2008). Synthesis and Antidepressant Activity of N-Substituted Imidazole-5-Carboxamides in Forced Swimming Test Model. Iranian Journal of Pharmaceutical Research, 7(1), 29-33.
  26. 26. Alan Hamilton (2004). Medicinal plants, conservation and livelihoods. Biodiversity & Conservation, 13(8), 1477-1517.
  27. 27. M Hussein,H Hameed,A Ibraheem (2016). Phytochemical Screening, GC-MS Analysis of Methanolic Extract of the Fern Adiantum Caudatum from Southern Western Ghats. Journal of Pharmaceutical Research, 8(2), 369-385.
  28. 28. Cne Ibezim,K Ugoeze (2017). The Antibacterial and Phytochemical Assessment of the Ethanolic Extracts of Parts of Cleome rutidosperma Plant. European Journal of Biomedical and Pharmaceutical Sciences, 4(10), 29-32.
  29. 29. E; Jafari,R Khajouei,F; Hassanzadeh,H Hakimelahi,A Khodarahmi,S G ; P; Ramya,A Radha (2016). GC-MS analysis and antibacterial activity of Cleome rutidosperma, Cleome gynandra and Cleome viscosa seed extracts: A comparative study. Journal of Pharmacognosy and Phytochemistry, 8(6), 500-508.
  30. 30. Jan Korbecki,Karolina Bajdak-Rusinek (2019). The effect of palmitic acid on inflammatory response in macrophages: an overview of molecular mechanisms. Inflammation Research, 68(11), 915-932.
  31. 31. Sumanta Mondal,Padilam Suresh (2012). Wound healing activity of Cleome rutidosperma DC. roots. International Current Pharmaceutical Journal, 1(6), 151-154.
  32. 32. I Morah,C Apebende (2018). Chemical composition, anthelmintic and antimicrobial activity of chloroform fraction of ethanol extract of Cleome rutidosperma. Edorium Journal of Public Health, 5, 1-6.
  33. 33. S Nalawade,Sagare,Lee Kao,C Tsay,H (2003). Studies on tissue culture of Chinese medicinal plant resources in Taiwan and their sustainable utilization. Bot Bull Acad Sin, 44, 79-98.
  34. 34. (2021). Preparedness of the CTSA's Structural and Scientific Assets to Support the Mission of the National Center for Advancing Translational Sciences (NCATS). Clinical and Translational Science, 5(2), 121-129.
  35. 35. M Nithin,G Veeramani,S Sivakrishnan (2020). Phytochemical screening and GC-MS Analysis of Rhizome of Drynaria quercifolia. Research Journal of Pharmacy and Technology, 13(5), 2266-2268.
  36. 36. Oludare Osuntokun,Gamberini Cristina (2019). Bio isolation, chemical purification, identification, antimicrobial and synergistic efficacy of extracted essential oils from stem bark extract of Spondias mombin(Linn). International Journal of Molecular Biology, 4(4), 135-143.
  37. 37. Oludare Osuntokun,Peace Ukwuoma,A Yusuf-Babatunde,O Ige (2017). Evaluation of Antimicrobial Activity, Phytochemical Screening and Gas Chromatography-Mass/ Spectrophotometric Profile of Essential Oil from Persea americana & Citrus sinensis. Asian Journal of Medicine and Health, 5(1), 1-17.
  38. 38. Yusuf Özkay,İlhan Işıkdağ,Zerrin İncesu,Gülşen Akalın (2010). Synthesis of 2-substituted-N-[4-(1-methyl-4,5-diphenyl-1H-imidazole-2-yl)phenyl]acetamide derivatives and evaluation of their anticancer activity. European Journal of Medicinal Chemistry, 45(8), 3320-3328.
  39. 39. Jyoti Pandey,Vinod Tiwari,Shyam Verma,Vinita Chaturvedi,S; Bhatnagar,S Sinha,A Gaikwad,Rama Tripathi (2009). Synthesis and antitubercular screening of imidazole derivatives☆. European Journal of Medicinal Chemistry, 44(8), 3350-3355.
  40. 40. Gabriella Pocsfalvi,Christopher Stanly,Immacolata Fiume,Károly Vékey (2016). Chromatography and its hyphenation to mass spectrometry for extracellular vesicle analysis. Journal of Chromatography A, 1439, 26-41.
  41. 41. A Puratchikody,Mukesh Doble (2007). Antinociceptive and antiinflammatory activities and QSAR studies on 2-substituted-4,5-diphenyl-1H-imidazoles. Bioorganic & Medicinal Chemistry, 15(2), 1083-1090.
  42. 42. M Refaat (2010). Synthesis and anticancer activity of some novel 2-substituted benzimidazole derivatives. European Journal of Medicinal Chemistry, 45(7), 2949-2956.
  43. 43. Periyar Sellamuthu,Balu Muniappan,Sathiya Perumal,Murugesan Kandasamy (2009). Antihyperglycemic Effect of Mangiferin in Streptozotocin Induced Diabetic Rats. Journal of Health Science, 55(2), 206-214.
  44. 44. K; Shalini,P Sharma,N Kumar (2010). Imidazole and its biological activities: A review. Der Chemica Sinica, 1(3), 36-47.
  45. 45. D; Sharma,B; Narasimhan,P; Kumar,V; Judge,R; De Narang,E; Clercq,J Balzarini (2009). Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives. 51. European Journal of Medicinal Chemistry, 44, 2347-2353.
  46. 46. Ramya Shingalapur,Kallappa Hosamani,Rangappa Keri (2009). Synthesis and evaluation of in vitro anti-microbial and anti-tubercular activity of 2-styryl benzimidazoles. European Journal of Medicinal Chemistry, 44(10), 4244-4248.
  47. 47. O Soyingbe,A Oyedeji,A O; Basoon,M Singh,A Opoku (2013). The chemical composition, antimicrobial and antioxidant properties of essential oil of Tulbaghia violaces Harv L.F. African. J Microbiol. Res, 7(18), 1789-1793.
  48. 48. Michele Tonelli,Matteo Simone,Bruno Tasso,Federica Novelli,Vito Boido,Fabio Sparatore,Giuseppe Paglietti,Sabrina Pricl,Gabriele Giliberti,Sylvain Blois,Cristina Ibba,Giuseppina Sanna,Roberta Loddo,Paolo La Colla (2010). Antiviral activity of benzimidazole derivatives. II. Antiviral activity of 2-phenylbenzimidazole derivatives. Bioorganic & Medicinal Chemistry, 18(8), 2937-2953.
  49. 49. A; Tsin,Betts-Obregon,J Grigsby (2018). Visual cycle proteins: Structure, function, and roles in human retinal disease. Journal of Biology and Chemistry, 293(34), 13016-13021.
  50. 50. Singumsetty Vinay,Shaik Karimulla,Devarajan Saravanan (2014). GC-MS analysis, preliminary phytochemical screening, physicochemical analysis and anti-diabetic activity of ethanol extract of <i>Jasminum cuspidatum</i> leaves. Bangladesh Journal of Pharmacology, 9(4), 610-616.
  51. 51. Abdul Wadood,M; ; Ghufran,S Jamal,M; B; B.S; Naeem,A; Khan,R Ghaffar,Asnad (2013). Phytochemical Analysis of Medicinal Plants Occurring in Local Area of Mardan. Biochemistry & Analytical Biochemistry, 02(04), 1-4.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Kenneth C. Ugoeze, Chidozie N. E. Ibezim, Nkemakolam Nwachukwu, Kennedy E. Oluigbo, Vincent O. Chukwube, Edebi N. Vaikosen, Sunday O. Abali. 2021. "GC-MS Evaluation of the Phytoconstituents of the Ethanolic and N-Hexane Extracts of the Whole Plant of Cleome Rutidosperma". Global Journal of Science Frontier Research - C: Biological Science GJSFR-C Volume 21 (GJSFR Volume 21 Issue C1).

Download Citation

Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

Keywords
Classification
GJSFR-C Classification FOR Code: 069999
Version of record

v1.2

Issue date
March 8, 2021

Language
English
Order Article Reprint
Experiance in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

Article Matrices
Total Views: 486
Total Downloads: 41
All Trends

Request Access

Please fill out the form below to request access to this research paper. Your request will be reviewed by the editorial or author team.
X

This is the heading

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.

High-quality academic research articles on global topics and journals.

GC-MS Evaluation of the Phytoconstituents of the Ethanolic and N-Hexane Extracts of the Whole Plant of Cleome Rutidosperma

Kenneth Ugoeze
Kenneth Ugoeze University of Port Harcourt
Chidozie Ibezim
Chidozie Ibezim
Nkemakolam Nwachukwu
Nkemakolam Nwachukwu
Kennedy Oluigbo
Kennedy Oluigbo
Vincent Chukwube
Vincent Chukwube
Edebi Vaikosen
Edebi Vaikosen
Sunday Abali
Sunday Abali