High-Flow Priapism Following Chlorpromazine Induced Low- Flow Priapism

α
Mohamed Saad Hegazy
Mohamed Saad Hegazy
σ
Mustafa MR
Mustafa MR
α Armed Forces College of Medicine

Send Message

To: Author

High-Flow Priapism Following Chlorpromazine Induced Low- Flow Priapism

Article Fingerprint

ReserarchID

7000F

High-Flow Priapism Following Chlorpromazine Induced Low- Flow Priapism Banner

AI TAKEAWAY

Connecting with the Eternal Ground
  • English
  • Afrikaans
  • Albanian
  • Amharic
  • Arabic
  • Armenian
  • Azerbaijani
  • Basque
  • Belarusian
  • Bengali
  • Bosnian
  • Bulgarian
  • Catalan
  • Cebuano
  • Chichewa
  • Chinese (Simplified)
  • Chinese (Traditional)
  • Corsican
  • Croatian
  • Czech
  • Danish
  • Dutch
  • Esperanto
  • Estonian
  • Filipino
  • Finnish
  • French
  • Frisian
  • Galician
  • Georgian
  • German
  • Greek
  • Gujarati
  • Haitian Creole
  • Hausa
  • Hawaiian
  • Hebrew
  • Hindi
  • Hmong
  • Hungarian
  • Icelandic
  • Igbo
  • Indonesian
  • Irish
  • Italian
  • Japanese
  • Javanese
  • Kannada
  • Kazakh
  • Khmer
  • Korean
  • Kurdish (Kurmanji)
  • Kyrgyz
  • Lao
  • Latin
  • Latvian
  • Lithuanian
  • Luxembourgish
  • Macedonian
  • Malagasy
  • Malay
  • Malayalam
  • Maltese
  • Maori
  • Marathi
  • Mongolian
  • Myanmar (Burmese)
  • Nepali
  • Norwegian
  • Pashto
  • Persian
  • Polish
  • Portuguese
  • Punjabi
  • Romanian
  • Russian
  • Samoan
  • Scots Gaelic
  • Serbian
  • Sesotho
  • Shona
  • Sindhi
  • Sinhala
  • Slovak
  • Slovenian
  • Somali
  • Spanish
  • Sundanese
  • Swahili
  • Swedish
  • Tajik
  • Tamil
  • Telugu
  • Thai
  • Turkish
  • Ukrainian
  • Urdu
  • Uzbek
  • Vietnamese
  • Welsh
  • Xhosa
  • Yiddish
  • Yoruba
  • Zulu

Abstract

Priapism is defined as a penile erection that persists more 4 hours or longer and is unrelated to sexual activity. The three main subtypes are low flow (ischemic), high flow (nonischemic) and stuttering (intermittent or recurrent) priapism. Alpha-1 antagonistic activities of some antipsychotics, especially chlorpromazine, have been reported to be responsible for development of low-flow priapism. Chlorpromazine has the greatest alpha-adrenergic affinity among the conventional antipsychotic agents and the most frequently reported to be associated with priapism. We report a case of priapism after a first single dose of chlorpromazine (Neurazine ® 100 mg tablet, Misr Co. For Phramind-Egypt). The case was presented first by neglected lowflow priapism that had been converted to high-flow priapism due to injury of a branch of the cavernosal artery, during aspiration and irrigation treatment procedure, proved by blood gas testing of the aspirated penile blood, penile color duplex Doppler ultrasonography and selective left internal pudendal arteriogram. This conversion is an uncommon complication of such procedure.

References

14 Cites in Article
  1. J Halls,D Patel,M Walkden,U Patel (2012). Priapism: pathophysiology and the role of the radiologist.
  2. Muharrem Baytunca,Sezen Kose,Burcu Ozbaran,Serpil Erermis (2016). Risperidone, quetiapine and chlorpromazine may have induced priapism in an adolescent.
  3. A Muneer,D Ralph (2017). Guideline of guidelines: priapism.
  4. Andrea Salonia,Ian Eardley,François Giuliano,Dimitrios Hatzichristou,Ignacio Moncada,Yoram Vardi,Eric Wespes,Konstantinos Hatzimouratidis (2014). European Association of Urology Guidelines on Priapism.
  5. C Wallis,N Hoag,P Pommerville,M Huk (2009). Recurrent idiopathic high-flow priapism treated with selective arterial embolization after repeated initial treatments for low-flow priapism.
  6. M Habous,M Elkhouly,O Abdelwahab (2016). Noninvasive treatments for iatrogenic priapism: Do they really work? A prospective multicenter study.
  7. M Shahrbabaki,L Sabzevari (2011). Early onset priapism under chlorpromazine and risperidone therapy.
  8. S Turkan,M Kalkan,C Şahin (2014). Two Priapism Cases Following Short-Term Use of Chlorpromazine.
  9. Mete Kilciler,Selahattin Bedir,Fahri Sümer,Murat Dayanç,Ahmet Peker (2003). Priapism in a Patient Receiving Long-Term Chlorpromazine Therapy.
  10. Frank Andersohn,Niklas Schmedt,Stefan Weinmann,Stefan Willich,Edeltraut Garbe (2010). Priapism Associated With Antipsychotics.
  11. I Marrag,R Soussia,Ben,K Hajji,L Zarrouk,Y Binous,M Nasr (2016). Priapisme induit par la chlorpromazine: A propos de deux cas.
  12. Austin Lutz,Stephen Lacour,Wayne Hellstrom (2012). Conversion of Low‐Flow to High‐Flow Priapism: A Case Report and Review (CME).
  13. C Mcmahon (2002). High flow priapism due to an arterial-lacunar fistula complicating initial veno-occlusive priapism.
  14. J Park,Y Jeong,Y Han,H Kim (2003). High‐flow priapism caused by injury of the bilateral cavernosal artery after needle trauma in a patient with low‐flow priapism.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Mohamed Saad Hegazy. 2018. \u201cHigh-Flow Priapism Following Chlorpromazine Induced Low- Flow Priapism\u201d. Global Journal of Medical Research - K: Interdisciplinary GJMR-K Volume 18 (GJMR Volume 18 Issue K5): .

Download Citation

Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords
Classification
GJMR-K Classification: NLMC Code: WK 900
Version of record

v1.2

Issue date

September 14, 2018

Language
en
Experiance in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

Article Matrices
Total Views: 3010
Total Downloads: 1558
2026 Trends
Related Research

Published Article

Priapism is defined as a penile erection that persists more 4 hours or longer and is unrelated to sexual activity. The three main subtypes are low flow (ischemic), high flow (nonischemic) and stuttering (intermittent or recurrent) priapism. Alpha-1 antagonistic activities of some antipsychotics, especially chlorpromazine, have been reported to be responsible for development of low-flow priapism. Chlorpromazine has the greatest alpha-adrenergic affinity among the conventional antipsychotic agents and the most frequently reported to be associated with priapism. We report a case of priapism after a first single dose of chlorpromazine (Neurazine ® 100 mg tablet, Misr Co. For Phramind-Egypt). The case was presented first by neglected lowflow priapism that had been converted to high-flow priapism due to injury of a branch of the cavernosal artery, during aspiration and irrigation treatment procedure, proved by blood gas testing of the aspirated penile blood, penile color duplex Doppler ultrasonography and selective left internal pudendal arteriogram. This conversion is an uncommon complication of such procedure.

Our website is actively being updated, and changes may occur frequently. Please clear your browser cache if needed. For feedback or error reporting, please email [email protected]

Request Access

Please fill out the form below to request access to this research paper. Your request will be reviewed by the editorial or author team.
X

Quote and Order Details

Contact Person

Invoice Address

Notes or Comments

This is the heading

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.

High-quality academic research articles on global topics and journals.

High-Flow Priapism Following Chlorpromazine Induced Low- Flow Priapism

Mohamed Saad Hegazy
Mohamed Saad Hegazy Armed Forces College of Medicine
Mustafa MR
Mustafa MR
Mustafa MR
Mustafa MR

Research Journals