High Grade Infiltrative Urothelial Carcinoma- Sarcomatoid Variant, A Rare Entity: Case Report And Review of Literature

High Grade Infiltrative Urothelial Carcinoma- Sarcomatoid Variant, A Rare Entity: Case Report And Review of Literature

Manas Madan

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Tejinder Singh Bhasin

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Mridu Manjari

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Manisha Sharma

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Bhawna

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to Baba Farid University of Health Sciences

High Grade Infiltrative Urothelial Carcinoma- Sarcomatoid Variant, A Rare Entity: Case Report And Review of Literature

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Abstract

In the urinary bladder, majority of the neoplasms are of pure epithelial origin. In contrast pure mesenchymal tumors and biphasic epithelial-mesenchymal neoplasms, although documented, rarely occur at this site Heterologous carcinosarcomas (also called metaplastic carcinomas or sarcomatoid carcinomas with heterologous differentiation) are defined as biphasic tumors made up of a varying mixture of carcinomatous and heterologous sarcomatous components with abrupt or gradual transition between one component and the other. These are rare tumors and account for approximately 0.3% of all bladder malignancies with a poor prognosis. Because of its unfavorable histopathologic nature and also its rarity, not much is known about the various treatment options in these tumors. The overall 5 year cancer specific survival rate after cystectomy is only 20.3%.

References

9 Cites in Article

Reference Format

Laurent Perret,Pascal Chaubert,Daniel Hessler,Louis Guillou (1998). Primary heterologous carcinosarcoma (Metaplastic carcinoma) of the urinary bladder.
D Atligan,B Parlaktas,N Uluocak,F Erdemir (2011). Sarcomatous carcinoma with osteosarcomatoid differentiation of the bladder with simultaneous sigmoid colon adenocarcinoma.
S Paick (2009). Sarcomatoid Urothelial Carcinoma of the Renal Pelvis with Extremely Aggressive Clinical Behavior.
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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Manas Madan. 2014. \u201cHigh Grade Infiltrative Urothelial Carcinoma- Sarcomatoid Variant, A Rare Entity: Case Report And Review of Literature\u201d. Global Journal of Medical Research - C: Microbiology & Pathology GJMR-C Volume 14 (GJMR Volume 14 Issue C7).

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

biphasic carcinosarcomas heterologous

Submission ReceivedDecember 6, 2013
Peer Review Double Blind
Handling Editor
Accepted January 3, 2014
Published January 15, 2014

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Issue date

December 24, 2014

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Article Matrices

Total Score: 105

Country: India

Subject: Global Journal of Medical Research - C: Microbiology & Pathology

Authors: Manas Madan, Tejinder Singh Bhasin, Mridu Manjari, Manisha Sharma, Bhawna (PhD/Dr. count: 0)

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Total Views: 4324

Total Downloads: 2243

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