Neural Networks and Rules-based Systems used to Find Rational and Scientific Correlations between being Here and Now with Afterlife Conditions
Neural Networks and Rules-based Systems used to Find Rational and
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Since the 1960s, mouse behavior has been systematically studied in the laboratory environment; however, there is still no consensus regarding the causes of aggression in laboratory animals. The involvement of the immune response in aggressive animal behavior has not been well elucidated. Different studies have found that the levels of interferon alpha (IFN-α), interleukin-6 (IL-6), and tumor necrosis factor alpha (TNF-α) are elevated in depressogenic/anxiogenic models. The aim of this study is to assess the correlations of serum cytokine (TNF, IL-6 and IL-10) levels with patterns of aggressive behavior (PBA). Our results suggest that mice exhibiting anxiety-like and highly aggressive behaviors have increased TNF serum levels and slightly decreased IL-10 levels. Additionally, a direct correlation was observed between high PBA scores and increased levels of TNF.
Fernanda da Silva Oliveira. 2014. \u201cIncreased TNF serum levels are related to highly aggressive behavior in male Swiss Webster mice\u201d. Global Journal of Medical Research - G: Veterinary Science & Medicine GJMR-G Volume 13 (GJMR Volume 13 Issue G2): .
Crossref Journal DOI 10.17406/gjmra
Print ISSN 0975-5888
e-ISSN 2249-4618
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Total Score: 108
Country: Brazil
Subject: Global Journal of Medical Research - G: Veterinary Science & Medicine
Authors: Fernanda da Silva Oliveira, Cynthia Machado Cascabulho , Kelly Cristina Demarque, JanaAna Alves Rangel, Frederico Villas Boas Rodrigues, Wanderson Silva Batista1, Lucas dos Santos Gameiro, Gabriel Melo de Oliveira (PhD/Dr. count: 0)
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Publish Date: 2014 01, Wed
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Since the 1960s, mouse behavior has been systematically studied in the laboratory environment; however, there is still no consensus regarding the causes of aggression in laboratory animals. The involvement of the immune response in aggressive animal behavior has not been well elucidated. Different studies have found that the levels of interferon alpha (IFN-α), interleukin-6 (IL-6), and tumor necrosis factor alpha (TNF-α) are elevated in depressogenic/anxiogenic models. The aim of this study is to assess the correlations of serum cytokine (TNF, IL-6 and IL-10) levels with patterns of aggressive behavior (PBA). Our results suggest that mice exhibiting anxiety-like and highly aggressive behaviors have increased TNF serum levels and slightly decreased IL-10 levels. Additionally, a direct correlation was observed between high PBA scores and increased levels of TNF.
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