Influence of Anti Diabetic Therapy on Plasma Lipid Profile and Its Relation to Erythrocyte Membrane Lipid Levels in Type 2 Diabetic Subjects

1
Dr. Basavaraj.S.Aski
Dr. Basavaraj.S.Aski
2
B.B.Devarnavadagi
B.B.Devarnavadagi
3
G. Rudrappa
G. Rudrappa
4
R.T.Kashinath
R.T.Kashinath
1 BLDE University SRI B.M.Patil Medical College BIJAPUR.

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The diabetes induced dyslipidemia may lead to an alteration in RBC membrane cholesterol/phospholipids ratio in diabetic subjects resulting in an alteration in RBC membrane properties. It has been observed in our laboratory that diabetes induced dyslipidemia causes a change in RBC membrane lipid composition in type 2 diabetic subjects. The effect of various oral anti diabetic drugs and or Insulin therapy on diabetes induced RBC membrane lipid alteration is not established. Hence the present work was undertaken to study the influence of anti diabetic drugs and or Insulin on RBC membrane lipid composition in type 2 diabetic subjects. Blood samples from randomly selected type 2 diabetic subjects were collected after obtaining written consent. The plasma lipids as well as RBC membrane lipids were estimated. The study group include normal subjects (group-1), control diabetics diabetic subjects (group-2), diabetic subjects receiving oral drugs (group-3), diabetic subjects receiving insulin (group-4) and diabetic subjects receiving both oral drugs and insulin (group-5).

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The authors declare no conflict of interest.

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Dr. Basavaraj.S.Aski. 1970. \u201cInfluence of Anti Diabetic Therapy on Plasma Lipid Profile and Its Relation to Erythrocyte Membrane Lipid Levels in Type 2 Diabetic Subjects\u201d. Unknown Journal GJMR Volume 12 (GJMR Volume 12 Issue 11): .

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January 8, 2013

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The diabetes induced dyslipidemia may lead to an alteration in RBC membrane cholesterol/phospholipids ratio in diabetic subjects resulting in an alteration in RBC membrane properties. It has been observed in our laboratory that diabetes induced dyslipidemia causes a change in RBC membrane lipid composition in type 2 diabetic subjects. The effect of various oral anti diabetic drugs and or Insulin therapy on diabetes induced RBC membrane lipid alteration is not established. Hence the present work was undertaken to study the influence of anti diabetic drugs and or Insulin on RBC membrane lipid composition in type 2 diabetic subjects. Blood samples from randomly selected type 2 diabetic subjects were collected after obtaining written consent. The plasma lipids as well as RBC membrane lipids were estimated. The study group include normal subjects (group-1), control diabetics diabetic subjects (group-2), diabetic subjects receiving oral drugs (group-3), diabetic subjects receiving insulin (group-4) and diabetic subjects receiving both oral drugs and insulin (group-5).

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Influence of Anti Diabetic Therapy on Plasma Lipid Profile and Its Relation to Erythrocyte Membrane Lipid Levels in Type 2 Diabetic Subjects

Dr. Basavaraj.S.Aski
Dr. Basavaraj.S.Aski BLDE University SRI B.M.Patil Medical College BIJAPUR.
B.B.Devarnavadagi
B.B.Devarnavadagi
G. Rudrappa
G. Rudrappa
R.T.Kashinath
R.T.Kashinath

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