Intoxication with Magnesium Sulfate in the Treatment of Eclampsia A Propos of Three Cases and Review of the Literature

souad mezzane

Intoxication with Magnesium Sulfate in the Treatment of Eclampsia A Propos of Three Cases and Review of the Literature

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Intoxication with Magnesium Sulfate in the Treatment of Eclampsia A Propos of Three Cases and Review of the Literature

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Abstract

Hypertensive diseases of pregnancy are among the first causes of severe maternal morbidity and mortality especially in developing countries. In developed countries, eclampsia is a rare event, but remains responsible for a significant maternal mortality. For over a century, magnesium sulfate is widely used in the United States in many obstetric indications including the treatment of eclampsia crises. There appears to be no consensus to treat or prevent seizures by magnesium sulfate. However, a large, multicentre, randomized trial compared the efficacy of magnesium sulfate with diazepam or phenytoin in eclamptic women. In this trial, magnesium sulfate was associated with a significantly lower rate of recurrent seizures and lower rate of maternal death than that observed with other anticonvulsants. The main objective of magnesium sulfate prophylaxis in women with preeclampsia is to prevent or reduce the rate of eclampsia and complications associated with eclampsia.

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28 Cites in Article

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1. M. Belfort,J. Anthony,B. Kirshon (1991). Respiratory function in severe gestational proteinuric hypertension: the effects of rapid volume expansion and subsequent vasodilatation with verapamil. Br J Obstet Gynecol, 98, 964-972.
2. Terrone DA,Rinehart BK,Kimmel ES,May WL,Larmon JE,Morrison JC (2000). A prospective, randomized, controlled trial of high and low maintenance doses of magnesium sulfate for acute tocolysis. Am J Obstet Gynecol, 182, 1477-82.
3. Grimes DA,Nanda K (2006). Magnesium sulfate tocolysis: time to quit. Obstet Gynecol, 108, 9869.
4. D. Altman,G. Carroli,L. Duley,B. Farrell,J. Moodley,J. Neilson,D. Smith (2002). Do women with pre-eclampsia, and their babies, benefit from magnesium sulphate? The Magpie Trial: a randomised placebo-controlled trial. The Lancet, 359, 1877-1890.
5. Baha Sibai (2005). Sibai BM. Diagnosis, prevention, and management of eclampsia. Obstetrics & Gynecology, 105(2), 402-410.
CrossRef DOI
6. Hupuczi P,Sziller I,Hruby E,Rigo B,Szabo G,Papp Z (2006). The rate of maternal complications in 107 pregnancies complicated with HELLP syndrome. Orv Hetil, 147, 1377-1385.
7. Sibai BM (2006). Preeclampsia As a Cause of Preterm and Late Preterm (Near-Term) Births. Semin Perinatol, 30, 16-19.
8. M. Chan,R. Boet,S. Ng,W. Poon,T. Gin (2005). Magnesium sulfate for brain protection during temporary cerebral artery occlusion. Acta Neurochir Suppl, 95, 107-111.
9. Sameshima H,Ota A,Ikenoue T (1999). Pretreatment with magnesium sulfate protects against hypoxic-ischemic brain injury but postasphyxial treatment worsens brain damage in seven-day-old rats. Am J Obstet Gynecol, 180, 725-730.
10. Sibai BM (1990). Magnesium sulfate is the ideal anticonvulsant in prééclampsie—eclampsia. Am J Obstet Gynecol, 162, 1141-1145.
11. J. Golding (1998). A randomised trial of low dose aspirin for primiparae in pregnancy The Jamaica low dose aspirin study group. Br J Obstet Gynecol, 105, 293-299.
12. The eclampsia collaborative group (1995). Which anticonvulsant for women with eclampsia ?Evidence from the collaborative eclampsia trial.Lancet 1995. The Lancet, 345, 1455-1463.
13. Witlin AG,Friedman SA,Sibai BM (1997). The effect of magnesium sulfate therapy on the duration of labor in women with mild preeclampsia at term: A randomized, double-blind, placebo-controlled trial. Am J Obstet Gynecol, 176, 623-627.
14. Belfort MA,Tooke-Miller C,Allen JC,Dizon- D,Varner MA (2002). LABETALOL DECREASES CEREBRAL PERFUSION PRESSURE WITHOUT NEGATIVELY AFFECTING CEREBRAL BLOOD FLOW IN HYPERTENSIVE GRAVIDAS. Hypertens Pregnancy, 21, 185-197.
15. A. Richards,L. Stather -Dunn,J. Moodley (1985). Richards A, Stather -Dunn L, Moodley J. Cardiopulmonary arrest after the administration of magnesium sulfate. S Afr Med J, 67, 145.
16. ACOG bulletin (2002). Diagnosis and management of preeclampsia and eclampsia. Obstet Gynecol, 99, 159-167.
17. P. Rozenberg (2006). Intérêt du sulfate de magnésium dans la prise en charge de la prééclampsie. Gynecol Obstet Fertil, 34, 54-59.
18. Duley L,Gulmezoglu AM,Henderson-Smart DJ (2003). Magnesium sulphate and other anticonvulsants for women with pre-eclampsia. Cochrane Database Syst Rev, 25.
19. Idama TO,Lindow SW Magnesium sulphate: a review of clinical pharmacology applied to obstetrics. Br J Obstet Gynaecol1998, 105, 260-268.
20. (2009). Recommandations formalisées d’experts communes. J Gynécol Obstet Biol Reprod, 38, 351-357.
21. Sibai BM (2004). Magnesium sulfate prophylaxis in preeclampsia: lessons learned from recent trials. Am J Obstet Gynecol, 190, 1520-1526.
22. P. Rozenberg (2006). Intérêt du sulfate de magnésium dans la prise en charge de la prééclampsie. Gynecol Obstet Fertil, 34, 54-59.
23. B. Girard,G. Beucher,C. Muris,T. Simonet,M. Dreyfus (2005). Sulfate demagnésium et prééclampsies sévères : utilisation en pratique courante. JGynecol Obstet Biol Reprod, 34, 17-22.
24. The Magpie Trial Collaborative Group (2002). Do women with pre-eclampsia, and their babies, benefit from magnesium sulphate? The Magpie Trial: a randomised placebo-controlled trial. The Lancet, 359, 1877-1890.
25. E. Coetzee,J. Dommisse,J. Anthony (1998). A randomised controlled trial of intravenous magnesium sulphate versus placebo in the management of women with severe pre‐eclampsia. Br J Obstet Gynaecol, 105, 300-303.
26. Belfort MA,Anthony J,Saade GR,Allen JC (2003). A Comparison of Magnesium Sulfate and Nimodipine for the Prevention of Eclampsia. N Engl J Med, 348, 304-311.
27. Baha Sibai (2005). Sibai BM. Diagnosis, prevention, and management of eclampsia. Obstetrics & Gynecology, 105(2), 402-410.
CrossRef DOI
28. Barrilleaux Isler CM,Magann Rinehart BK (2003). Postpartum seizure prophylaxis: Using maternal clinical parameters toguide therapy. Obstet Gynecol, 101, 66-69.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

souad mezzane. 2014. "Intoxication with Magnesium Sulfate in the Treatment of Eclampsia A Propos of Three Cases and Review of the Literature". Global Journal of Medical Research - E: Gynecology & Obstetrics GJMR-E Volume 14 (GJMR Volume 14 Issue 5 (E1)).

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GJMR Volume 14 Issue 5 (E1)

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

eclampsie intoxication pré-éclampsie sulfate de magnésium traitement

Classification

GJMR-E Classification NLMC Code: WJ 140

Submission ReceivedDecember 10, 2013
Peer Review Double Blind
Handling Editor
Accepted January 1, 2014
Published February 7, 2014

Version of record

v1.2

Issue date

February 7, 2014

Language

French

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Total Score: 127

Country: Morocco

Subject: Global Journal of Medical Research - E: Gynecology & Obstetrics

Authors: S. Mezane, M. Achnani, M. Ziyadi, A. Babahabib, R. Hafidi, D. Moussaoui, M. Dehayni (PhD/Dr. count: 0)

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