Intoxication with Magnesium Sulfate in the Treatment of Eclampsia A Propos of Three Cases and Review of the Literature

Intoxication with Magnesium Sulfate in the Treatment of Eclampsia A Propos of Three Cases and Review of the Literature

souad mezzane

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S. Mezane

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M. Achnani

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M. Ziyadi

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A. Babahabib

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R. Hafidi

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D. Moussaoui

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M. Dehayni

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Mohammed V University

Intoxication with Magnesium Sulfate in the Treatment of Eclampsia A Propos of Three Cases and Review of the Literature

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Abstract

Hypertensive diseases of pregnancy are among the first causes of severe maternal morbidity and mortality especially in developing countries. In developed countries, eclampsia is a rare event, but remains responsible for a significant maternal mortality. For over a century, magnesium sulfate is widely used in the United States in many obstetric indications including the treatment of eclampsia crises. There appears to be no consensus to treat or prevent seizures by magnesium sulfate. However, a large, multicentre, randomized trial compared the efficacy of magnesium sulfate with diazepam or phenytoin in eclamptic women. In this trial, magnesium sulfate was associated with a significantly lower rate of recurrent seizures and lower rate of maternal death than that observed with other anticonvulsants. The main objective of magnesium sulfate prophylaxis in women with preeclampsia is to prevent or reduce the rate of eclampsia and complications associated with eclampsia.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

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Not applicable for this article.

How to Cite This Article

souad mezzane. 2014. \u201cIntoxication with Magnesium Sulfate in the Treatment of Eclampsia A Propos of Three Cases and Review of the Literature\u201d. Global Journal of Medical Research - E: Gynecology & Obstetrics GJMR-E Volume 14 (GJMR Volume 14 Issue E1).

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

eclampsia intoxication magnesium sulfate preeclampsia Treatment

Submission ReceivedDecember 10, 2013
Peer Review Double Blind
Handling Editor
Accepted January 1, 2014
Published January 15, 2014

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v1.2

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April 15, 2014

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Article Matrices

Total Score: 127

Country: Morocco

Subject: Global Journal of Medical Research - E: Gynecology & Obstetrics

Authors: S. Mezane, M. Achnani, M. Ziyadi, A. Babahabib, R. Hafidi, D. Moussaoui, M. Dehayni (PhD/Dr. count: 0)

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