Is it Possible Artificial Sex Regulation in Mammals?

A.I. Ibraimov

Is it Possible Artificial Sex Regulation in Mammals?

A.I. Ibraimov * §

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Kazakh National Medical University

Is it Possible Artificial Sex Regulation in Mammals?

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Abstract

In spite of, impressive breakthrough in modern genetics and molecular biology the problem of artificial sex regulation of mammals still remains unsolved. Moreover, the very problem of sex origin of eukaryotes in the process of evolution still has not settled. Existing theories and hypothesizes mainly concern the maintenance and biological reasonability of sexual mode of replication. Their theoretic foundation is based on Darwin’s and Mendel’s ideas that sex was originated due to natural selection and genes. On the basis of other model of genesis and sex evolution of eukaryote, it was suggested the idea of artificial sex regulation of mammals. Seemingly, the sex differentiation (SD) in animals and human is determined by the amount of constitutive heterochromatin region (cHR) in the Y chromosomes of the undifferentiated embryonic gonads (UEG) via cell thermoregulation. It is assumed the medulla and cortex tissue cells in the UEG differ in vulnerability to the increase of the intracellular temperature because of their anatomical position in genital ridges. If the amount of the cHR on Y chromosome is enough for efficient elimination of redundant metabolic heat from rapidly growing UEG cells the medulla tissue survives. Otherwise it doomed to degeneration and a cortex tissue will remain in the UEG. For artificial regulation of the SD it is proposed to remove a layer of cortex in the UEG.

References

22 Cites in Article

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

A.I. Ibraimov. 2013. "Is it Possible Artificial Sex Regulation in Mammals?". Global Journal of Science Frontier Research - G: Bio-Tech & Genetics GJSFR-G Volume 13 (GJSFR Volume 13 Issue G2).

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GJSFR Volume 13 Issue G2

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Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

Keywords

cell thermoregulation constitutive heterochromatin genital ridges non coding DNAs sex differentiation sex regulation Y chro-mosome

Classification

GJSFR-G Classification FOR Code: 270205

Submission ReceivedSeptember 22, 2013
Peer Review Double Blind
Handling Editor
Accepted October 15, 2013
Published October 30, 2013

Version of record

v1.2

Issue date

October 30, 2013

Language

English

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Total Score: 145

Country: Kyrgyzstan

Subject: Global Journal of Science Frontier Research

Authors: A.I. Ibraimov (PhD/Dr. count: 0)

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