Is there a relationship between intraoperative bispectral index and cognitive impairment after coronary artery surgery?

α
Dr. Judith A. Hudetz
Dr. Judith A. Hudetz
σ
Zafar Iqbal
Zafar Iqbal
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Sweeta D. Gandhi
Sweeta D. Gandhi
Ѡ
Kathleen M. Patterson
Kathleen M. Patterson
¥
Paul S. Pagel
Paul S. Pagel
α Medical College of Wisconsin Medical College of Wisconsin

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Is there a relationship between intraoperative bispectral index and cognitive impairment after coronary artery surgery?

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Abstract

We examined the relationship between short- and medium-term POCD and anesthetic depth using bispectral index (BIS) values in patients undergoing coronary artery bypass graft (CABG) surgery using cardiopulmonary bypass (CPB). We identified 89 patients in whom BIS monitoring was used. Memory and executive functions were assessed before, one week, and three months after surgery. Two cognitive tests showed at least two standard deviation (SD) decrease from baseline in patients one week after surgery. After three months, six tests showed at least one SD decrease from baseline. BIS scores were significantly higher after CPB in patients with versus without POCD one week after surgery. The BIS scores during and after CPB and throughout the surgery were also higher in patients with versus without POCD three months after surgery. The results suggest that there may be a relationship between POCD and anesthetic depth in patients undergoing CABG.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Dr. Judith A. Hudetz. 1970. \u201cIs there a relationship between intraoperative bispectral index and cognitive impairment after coronary artery surgery?\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine N/A (GJMR Volume 11 Issue B4): .

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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English
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We examined the relationship between short- and medium-term POCD and anesthetic depth using bispectral index (BIS) values in patients undergoing coronary artery bypass graft (CABG) surgery using cardiopulmonary bypass (CPB). We identified 89 patients in whom BIS monitoring was used. Memory and executive functions were assessed before, one week, and three months after surgery. Two cognitive tests showed at least two standard deviation (SD) decrease from baseline in patients one week after surgery. After three months, six tests showed at least one SD decrease from baseline. BIS scores were significantly higher after CPB in patients with versus without POCD one week after surgery. The BIS scores during and after CPB and throughout the surgery were also higher in patients with versus without POCD three months after surgery. The results suggest that there may be a relationship between POCD and anesthetic depth in patients undergoing CABG.

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Is there a relationship between intraoperative bispectral index and cognitive impairment after coronary artery surgery?

Dr. Judith A. Hudetz
Dr. Judith A. Hudetz Medical College of Wisconsin
Zafar Iqbal
Zafar Iqbal
Sweeta D. Gandhi
Sweeta D. Gandhi
Kathleen M. Patterson
Kathleen M. Patterson
Paul S. Pagel
Paul S. Pagel

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